There is so much truth in this article: www.theguardian.com/commentisfre...

Imaging spotlight: Calibrating expansion microscopy to map receptor sorting domains in endosomes - FocalPlane Imaging spotlight: Calibrating expansion microscopy to map receptor sorting domains in endosomes - News

🔬🔦In their Imaging spotlight, @taylashakespeare.bsky.social and @ijayas.bsky.social highlight their research dissecting receptor sorting in endosomes using the calibrated 3D ExM toolkit that they developed.
focalplane.biologists.com/2026/04/15/i...

As long as it has a Nature prefix, there will always be some folks who want to turn that into a competition. Why else are there the NPJ journals now? Honestly.

Imaging spotlight: Calibrating expansion microscopy to map receptor sorting domains in endosomes - FocalPlane Imaging spotlight: Calibrating expansion microscopy to map receptor sorting domains in endosomes - News

Now you can check out our paper highlights in our @focalplane.bsky.social blog post!

We demonstrate the use of a calibrated ExM toolkit to visualise complex nanodomain architectures at membrane-bound organelles in the cell ▫️➡️ ⬜ 🔬

focalplane.biologists.com/2026/04/15/i...

Nanosize rulers help correct distortion in inflated cells Nanosize rulers and computer analysis help fix uneven inflation of organelles

Delighted to see our recent work on the use of self-assembling nanoscale calibrants for detecting errors in #ExpansionMicroscopy, particularly in visualising the biology of small organelles such as endosomes, featured in C&EN.

cen.acs.org/analytical-c...

And if you are from a certain generation, it’s “Tioosdi”

Here is the post on the research paper:

Nanosize rulers help correct distortion in inflated cells Nanosize rulers and computer analysis help fix uneven inflation of organelles

Delighted to see our recent work on the use of self-assembling nanoscale calibrants for detecting errors in #ExpansionMicroscopy, particularly in visualising the biology of small organelles such as endosomes, featured in C&EN.

cen.acs.org/analytical-c...

The reply from Cambridge is almost as gross as the Goldhill’s behaviour. They sit behind the veil of confidentiality, but nothing ever changes. No amount of newspaper coverage will shift this, I am afraid.

So many places here named after English aristocrats who graced Australia with their visits.

That’s not even the worst.

Google:

Batman, VIC

I think it’s a perfectly sensible and normal thing to take your cousin’s Faberge egg and watch collection into a pub. Isn’t this the premise of all Guy Richie movies?

Do you think journal should be using tools to screen for AI generated text or figures?

I know that with journals like @natcomms.nature.com, they don’t want to have any email correspondence with reviewers once they have accepted the review request. They will just badger you to finish the review.

Google defines it as, “the expertise-driven practice of sharing insightful, high-value ideas that influence, educate, and shape industries”. Honestly it sounds like the sort of drivel that self proclaimed experts would say that makes me look for the nearest fire escape.

These are perfectly normal file/folder names. But why so many blurry cells?

How to be a science sleuth:
Research integrity experts share their tips for spotting and reporting fraudulent papers
Rupali Dabas writes @chemistryworld.com
Featuring @smutclyde.bsky.social , @deevybee.bsky.social, Nick Wise, Jack Wilkinson, Anna Pendlebury, and me.

Priorities. Posted at 1:47 pm like a true Australian prof.

Universities in the Global North & Legacies of Slavery How can we use a structure to repair damage done by said structure?

On this International Day of Remembrance of the Victims of Slavery and the Transatlantic Slave Trade, a reminder that universities need to go much deeper in 'acknowledging links' to the trade in enslaved Africans. What about what was LOST & continues to be lost?
folukeafrica.com/universities...

It’s amazing 🥰

It’s not just practice, but attitudes that need to change. Many still think that acquiring the images is the end-point to an experiment.

… affecting long-term professional success as well as health and well-being”

Really feeling it this week.

“BIPOC scientists face additional hurdles. Their path through the academy’s obstacle course is harder because of racial discrimination that may manifest itself as dismissiveness, harassment, or exclusion from formal and informal professional opportunities…

Scientists from historically excluded groups face a hostile obstacle course - Nature Geoscience Inclusive and equitable geoscience requires identification and removal of structural barriers to participation. Replacing the leaky pipeline metaphor with that of a hostile obstacle course demands tha...

Sharing this 🎯 paper from a few years, for no particular reason, with the apt metaphor that academia is a hostile obstacle course.

It’s a paper that seems to become more relevant as time goes on, not just in the US, but also in the far reaches of the academic map.

elmo from sesame street is standing in front of a drawing on the wall Alt: elmo from sesame street is standing in front of a drawing on the wall

Happy birthday @needhibhalla.bsky.social!

A surface rendered view of an endosome. The endosome surface is rendered in blue with dimples on it. In specific regions of the endosomal surface, clusters of proteins are seen as aggregates of blobs, coloured in yellow and red.

🚨New paper out today in @acs.org ACS Nano, showing how expansion microscopy can visually quantify the cell surface receptor turnover mediated by signalling & receptor organising machineries on the surfaces of endosomes, some of the smallest organelles in cells. 🧪 🔬 1/ pubs.acs.org/doi/10.1021/...

“Harvey also loves growling at and chewing on the legs of passing pedestrians. It’s not personal, just ignore him”

Many congratulations to the team of collaborators, especially Tayla Shakespeare and @rajseehra.bsky.social who have achieved this with the guidance and support of a whole team, including Philip Woodman (Manchester) and @drbciani.bsky.social. 4/

(ii) a protocol for mapping sub-micron-scale errors in ExM gels (b/c even the most robust gel chemistries can have local heterogeneity), & (iii) a surface tracing tool that could be useful for reconstructing *relatively round* organelles, esp when it's useful to see their shape & topology in 3D. 3/

Along the way, we developed a suite of tools that will make expansion microscopy more quantitative & (hopefully) more usable, including (i) a nanoscale calibrant of the expansion factor - a natively expressed protein nanocage shared by Prof David Baker's lab that reports local under-expansion 2/