I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...
Crazy things have been happening in cilia world, catch up on them in Caitie's new paper! 🪱
You’re welcome ☺️
Thrilled to share that our paper on a novel IRD gene has been published in The American Journal of Human Genetics (AJHG)! 🎉 This wouldn’t have been possible without the incredible group of colleagues and collaborators. Special thanks to @computingcaitie.bsky.social, Ditta Zobor, and ERDC members!
I’m happy to share that the latest work from the @carlorivolta.bsky.social lab, thanks to a huge international collaborative effort, is now out in Nature Genetics!🧬
Congratulations to all, but especially to @mquinodoz.bsky.social and @kimrodenburg.bsky.social for leading this impressive work!
No momentum lost as we dazzled with the ciliary necklace, CEP290 and transition zone integrity in #photoreceptors, inner scaffold maintenance & membrane attachment key for gating with the amazing @abimoye.bsky.social (Wensel group and current @carlorivolta.bsky.social ). #IRDs #UKCilia2025 /4
Yes! That is the best idea
Happy Halloween! Cilia can be spooky too 🎃
Super happy this work is out and included in the really interesting cilia and flagella focused issue!
Agreed! Great getting to chat! 😄
Save the date!! ✨🤩
🚨 CALL FOR APPLICATIONS 🚨
Looking for your next academic step?
Join our interdisciplinary IOB MD-PhD / PhD Program to explore the visual system and pioneer therapies for eye diseases.
⏰ Deadline: November 16, 2025 (midnight CET)
🔗 iob.ch/phd-md-phd-program
#IOB #Basel #PhDProgram #VisionScience
Hahaha yes! I felt like I was betraying myself getting excited this week 😂
I am normally focused on photoreceptor cilia, but this week I worked with an amazing lung epithelial tissue model and I can see the #motilecilia appeal 🤩 so fascinating! Happy #fluorescencefriday everyone!
Thank you!! Great meeting you 😄
Really cool Moe!!! Can’t wait to hear 😃
Looking for a break from scientific reading, and want to delve into the realm of environmental philosophy? Check out this thought-provoking article by Charles Hayes published in Environmental Ethics. Interesting and insightful look into what my brother studies daily! www.pdcnet.org/enviroethics...
New hope for inherited vision loss
IOB researchers (@karkam.bsky.social, @carlorivolta.bsky.social, @mquinodoz.bsky.social, @abimoye.bsky.social) identify AP5Z1, AP5M1, AP5B1 mutations, revealing new causes of macular dystrophy.
🔗 www.cell.com/ajhg/fulltex...
#AcademicBlueSky #Ophthalmology
Thanks!
Early ciliogenesis occurs in CEP290-knockout photoreceptors. BUT our nano-scale ultrastructural analyses discovered alterations in the architecture of ciliary membrane complexes, including the Y-links and ciliary necklace that underlie cilium failure and neurodegeneration later in development.
e also provide the first comprehensive nanoscale localization of CEP290 in human rod and cone photoreceptor cells.
Excited to share our ✨preprint✨ from my work in Ted Wensel's lab! We present novel insights into the photoreceptor-specific roles of CEP290. 🧵👇 Thanks for the helpful participation from everyone involved, especially @mrobichaux.bsky.social and @agostolab.bsky.social! www.biorxiv.org/content/10.1...
Great gene editing study from a highly interdisciplinary team at @iobswiss.bsky.social. Congratulation to all authors, in particular Alissa Muller, Botond Roska & Bence György.
www.nature.com/articles/s41...
#AcademicSky #neuroscience
Or parents taking their kids to school on sleds
