Using cryo-EM, we captured five structural intermediates of the Nudaurelia capensis omega virus (NωV) as it matures from procapsid to infectious virion. It's incredibly exciting to see the complete maturation pathway of a eukaryotic virus described at this level of detail.
It took a while but it’s finally published!
The GAP activity of SEAC (GATOR) is a metabolic switch that allows cells to quickly respond to changes in amino acid levels, both for inhibition and reactivation.
Structural basis for TORC2 activation www.biorxiv.org/content/10.1101/2025.07....
Unbelievable!
Interested in how nutrients regulate cellular growth and metabolism?
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www.cnio.es/en/empleo/pr...
Where did she write this?
How many of the PDB models that were solved using experimental phasing could have been solved by molecular replacement using models obtained from AlphaFold? #MolecularReplacement #AlphaFold2 #ComputationalMethods t.co/s6EahtcYms
First post here! ✨🦋
There is still time to apply! We have a postdoc position open in our lab at Aarhus University 🇩🇰
We study DNA repair 🧬, combining biochemistry, structural biology, and single-molecule imaging 🔬
Learn more about our research, lab, and Aarhus:
sites.google.com/view/alconla...
We report publications that include PDB ids with & without citation.
Here is an example from a 🥝 protein structure determined by X-ray crystallography:
www.ebi.ac.uk/pdbe/entry/p...
Here is an exampe from a virus complex structure impacting 🍇 determined by #cryoEM. www.ebi.ac.uk/pdbe/entry/p...