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Posts by Joshua Shapiro

Sorry for the black humor. Congratulations!

2 days ago 2 0 1 0

Based on your location, were you expecting bad news?

2 days ago 3 0 1 0

I wish them luck, but "American Racing Challenger Team USA" just sounds horribly fake and made up.

#americascup

2 days ago 2 0 0 0
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NSF LTER program “archived”.

LTER=“Long Term Ecological Research”.

This program has been incredibly successful, incredibly frugal for what they accomplish, and…of course…targeted by evil know-nothings.

My heart is breaking.

5 days ago 374 182 18 58

America is being damaged by people who apply zero-sum thinking to everything from housing to higher ed.

If more international students come, we’ll make more colleges, or just stop closing them by the hundreds! College admissions aren’t a contest for a fixed number of seats.

6 days ago 33 6 1 0
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Cancer research, dismantled.

Only *35* grants awarded so far in FY26.

NCI stats for new and competitive grant renewals from: grant-witness.us/funding_curv...

1 week ago 10 8 0 1
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Federal Judge Approves Trump Effort to Obtain List of Jews From Penn

personally I think "Federal Judge Approves Trump Effort to Obtain List of Jews From Penn" is a bad thing to read in the newspaper

www.nytimes.com/2026/03/31/u...

1 week ago 1327 352 33 59
Headline: Tracking the Major Supreme Court Cases and Rulings This Year

Headline: Tracking the Major Supreme Court Cases and Rulings This Year

Misread this as “Trashing the Major Supreme Court Rulings..” and was briefly excited.

1 week ago 2 0 0 0

I often call it the thirstiest social network. I don’t have any experience on dating sites, but I’m still pretty sure that’s correct.

1 week ago 0 0 0 0

Trying not to humblebrag, but I always find it funny when LinkedIn casually suggests I might want to connect with a Nobel laureate because I happened to work as a postdoc in a nearby department. I mean yeah, I talked to them a couple times, but I’m not that thirsty.

1 week ago 3 0 1 0
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My contribution the scientific discourse about a certain movie: that liked like a speedvac or at best a low speed centrifuge. It would be fine. Way more fine than working with alien microbes in an open lab.

1 week ago 0 0 0 0

My contribution the scientific discourse about a certain movie: that liked like a speedvac or at best a low speed centrifuge. It would be fine. Way more fine than working with alien microbes in an open lab.

1 week ago 0 0 0 0

Congratulations!

1 week ago 1 0 0 0

I want to groan, but I find myself liking this.

2 weeks ago 0 0 0 0

So what happens if they violate the law and don’t nominate anyone? Nothing. Nothing happens.

Also, the hilarious idea of finding someone who agrees with RFK Jr but isn’t antivax…

2 weeks ago 2 0 0 0
Four colored scale bars in the corners of an otherwise blank image

Four colored scale bars in the corners of an otherwise blank image

Example extraction; labeled as Figure 8 (there are 6 figures in the paper)

2 weeks ago 1 0 1 0

I thought that extracting figures from a scientific paper would be one of the things an AI could do well. I was very wrong.

2 weeks ago 5 1 1 0

Got to go whitewater kayaking with both my boys today. Can’t complain.

3 weeks ago 3 0 0 0
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David Botstein, Gene-Mapping Pioneer, Dies at 83

David Botstein was one of the giants of genetics and genomics, and my mentor, colleague and friend for more than 40 years. I’m sad that he is gone, but his larger-than-life persona comes through here. www.nytimes.com/2026/03/20/s...

3 weeks ago 122 36 4 3
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At a talk about molecular glue degraders: Covalent Warheads is my next metal band name.

3 weeks ago 1 0 0 0

And the stretching to claim that what they are doing is in any way related to preventing loss of extant species...

3 weeks ago 3 1 1 0
a headshot of David Botstein

a headshot of David Botstein

We are deeply saddened to share the news of the passing of David Botstein, a towering figure in modern #genetics and a foundational force behind SGD.
www.yeastgenome.org/blog/in-memo... #yeast #modelOrganism

1 month ago 53 29 0 3

I’d put it closer to 0/10.

1 month ago 1 0 0 0

I worked in the adjacent lab when I was postdoc at Princeton, and David Botstein’s influence could not be overstated. I never had a conversation with him where I didn’t learn something. He’ll be missed to be sure.

1 month ago 7 0 0 0
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David Botstein | 1942 - 2026 | Online-Tribute.com David was a beloved husband, father, brother, scientist, teacher, mentor, musician, friend, who touched the lives of thousands. David’s wide-ranging scientific career spanned decades with a legacy o…

Crap

www.online-tribute.com/DavidBotstein

David Botstein passed away. I worked with him at Stanford for a few years in designing and teaching a course on "The Heart". My heart is heavy right now. He was a wonderful mentor.

1 month ago 108 16 5 6

I’m honestly kind of shocked that the word was used in the paper.

1 month ago 0 0 0 0

I know you’re joking, but that is absolutely the worst interpretation of the data. There is absolutely nothing about preference there. Bias in direction of interbreeding, sure, but preferences far from the only explanation for that, let alone the first we should go to.

1 month ago 1 0 1 0
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AIs can’t stop recommending nuclear strikes in war game simulations Leading AIs from OpenAI, Anthropic and Google opted to use nuclear weapons in simulated war games in 95 per cent of cases

Still haven't gotten the AIs to learn that the only winning move is not to play. www.newscientist.com/article/2516...

1 month ago 1 0 0 0

It was a good day to shovel snow and make chili.

1 month ago 5 0 0 0

Is Good Luck, Have Fun, Don’t Die a great movie? Not really. Was it fun? Yes. Did it have maximum Rockwell? Absolutely, and that was all I was asking for.

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