Opportunities and pitfalls of data contextualization in neuroimaging — a Roadmap by Jessica Royer, Casey Paquola, Sara Larivière, Justine Y. Hansen, Sofie L. Valk, Bratislav Misic, Robert Leech, Jonathan Smallwood & Boris C. Bernhardt
#neuroscience #neuroskyence
www.nature.com/articles/s41...
Correlating brain maps across datasets is everywhere in neuroimaging. Here we ask: when you contextualize a brain map against genes, metabolism, or connectivity... What can you really conclude? How can we do better? We explore these questions here: tinyurl.com/2dudkevc
preprint🥳
Connectome-wide mega-analysis identifies a reproducible functional network signature of temporal lobe epilepsy
-hypo+hyper connectivity
-patient/site consistent
-constrained by 🧠 wiring
-tracks clinical status and info for outcome
by @kexie.bsky.social et al
doi.org/10.64898/202...
🚀 We are hiring: a PhD position is available in my lab (gozzilab.it) at @iitalk.bsky.social, Italy. Project: large-scale brain network mapping in behaving mice using functional ultrasound imaging (FUSI).
📅 Deadline: March 31
🔗 tinyurl.com/4jtetxa9
Reshares appreciated 😊
I tracked every keyword in 22 years of Cosyne abstracts to map how computational neuroscience evolved — from Bayesian brains to neural manifolds to LLMs — and where it's heading next.
Histology-based SWM microstructure intensity profile. Top: SWM sampling framework from 3D postmortem histology. The Laplacian field within the white matter domain was solved for each histological classified volume to sample 50 SWM surfaces, spanning from the GM/WM interface to 3 mm into the white matter. These surfaces were then mapped to each histological staining method, allowing the extraction of intensity profiles for each vertex across SWM depths. Bottom: Alterations in the intensity distributions of histological features across SWM depths. The GM/WM interface (0 mm) and 25 representative SWM surfaces (up to 3 mm into the white matter) are shown. The surfaces showing the greatest variation in SWM, from 0 to 1.8 mm into the white matter, were mapped onto the brain alongside the intensity profiles on the left.
How does superficial white matter contribute to large-scale #brain function? @borismontreal.bsky.social &co use an approach based on 3D histology & 7-Tesla MRI to reveal associations between superficial #WhiteMatter microstructure & diverse cortical properties @plosbiology.org 🧪 plos.io/460WNIz
Very happy to see this last thesis paper in press @natcomms.nature.com! We combine intracranial EEG with multimodal MRI to study how interregional similarity in neurophysiology relates to different network scales ⚡ 🧠
Full story 👇
www.nature.com/articles/s41...
🍤 hippocampus = the brain's memory machine 🍤
unique cytoarchitecture, highly connected with multiple networks, & very variable across individuals
video shows hippocampal shape variations across 250-ish young HCP adults
study hippocampus with open tools like hippomaps doi.org/10.1038/s415...
When your PI presents your work
this is mesmerizing
📢 Publication Alter!
🎉 Excited to share that our work, “Personalized biomarkers of multiscale functional alterations in temporal lobe epilepsy”, is now out in Nature Communications #TLE #MRI #biomarker
🔗 Full paper: rdcu.be/eQKLX
📣 Full post (credit to @borismontreal.bsky.social): bit.ly/48uJL7r
Still think this was one of the best power moves of all time
www.sciencedirect.com/science/arti...
New preprint ↙️
Using 2 independent 7T fMRI datasets (HCP & our PNI dataset 🧲 💅 ), we found that intersubject synchronization 👯 during movies aligns closely with cortical gradients 🌈, especially along the visual-to-transmodal axis
by Meaghan Smith & a terrific team ↙️
doi.org/10.1101/2025...
oh wowwwwwwwwwwwwww thats really cool 🤩
For researchers in Canada and the USA 👇
Online info session about ERC research grants, on Wednesday, October 15th, 2025 at 12:00 noon ET (9:00 AM PT, 6:00 PM CEST).
The meeting is free but advance registration is required.
euraxess.ec.europa.eu/worldwide/no...
HippoMaps: an open-source resource for studying the human hippocampus at different scales and with different modalities.
www.nature.com/articles/s41...
@jordandekraker.bsky.social @borismontreal.bsky.social @jclauneuro.bsky.social @neuroak.bsky.social @sofievalk.bsky.social @donnagift.bsky.social
congratulations Armin!!!
🚨 New paper in Nature Methods:
HippoMaps: multiscale cartography of the human hippocampus
Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG)
Led by @jordandekraker.bsky.social
docs: hippomaps.readthedocs.io
paper: doi.org/10.1038/s415...
Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
Interested in the mechanisms shaping the extraordinary complexity of the connectome?
Then check out our new preprint, lead by
Francis Normand with a stellar team, showing how geometry constrains connectome architecture:
biorxiv.org/content/10.1...
Full thread here:
tinyurl.com/sfv3yf73
There is increasing interest in using AI tools not only to listen in on animal speech, but also to potentially talk back
go.nature.com/4pqGYCP
The peer review process: 3 strangers yelling “more cowbell” at your life's work
Interested in hippocampal dynamics and their interactions with cortical rhythms?
Our physically constrained model of cortico-hippocampal interactions - complete with fast geometrically informed numerical simulation (available at embedded github repo)
www.biorxiv.org/content/10.1...
The effect of spherical projections on spin tests for brain maps | doi.org/10.1162/IMAG...
Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️
The Dept. of Psychology at the U. Wisconsin–Madison has an opening for an Assistant Professor in the area of Computational Neuroscience and/or Cognitive Science, with an emphasis on artificial intelligence (AI).
Domain of behavior or cognition is open. Details at jobs.wisc.edu/jobs/assista...
Come join us at University of Toronto. We're hiring a Professor of computational cognitive neuroscience.
#neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...
🚨 𝗔̲𝗯̲𝘀̲𝘁̲𝗿̲𝗮̲𝗰̲𝘁̲ ̲𝗗̲𝗲̲𝗮̲𝗱̲𝗹̲𝗶̲𝗻̲𝗲̲ ̲𝗔̲𝗽𝗽𝗿̲𝗼̲𝗮̲𝗰̲𝗵̲𝗶̲𝗻̲𝗴!̲ 🚨
The Neuroimaging of Epilepsy Worldwide (NEW) is hosting, for the second year in a row, a networking and talk session at the Annual Meeting of the CLAE/LCCE in Calgary 🐎.
1/3
🔥🧠Excited to announce that I am recruiting PhD students this fall. Our lab uses neuroimaging (MRI) and computational modeling to study the mechanisms of neurodevelopmental disorders, bridging genetic factor, brain circuitry, early life stress, and psychopathology. Please feel free to DM me.
