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Posts by Amritesh Sarkar

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Microplastics and nanoplastics were found in 100% of healthy brains, 99.4% of diseased brains, with much higher concentrations adjacent to brain tumors
nature.com/articles/s44...

2 days ago 159 58 7 7
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Human hippocampal neurogenesis in adulthood, ageing and Alzheimer’s disease - Nature Mapping of neurogenesis in human hippocampi across ages and different cognitive abilities using multiomic single-cell sequencing reveals distinct signatures between cognitive preservation and decline.

New @nature.com
The brains of Super Agers produce more neurons than people some 50 years younger, a neurogenesis resilient signature linked to exceptional cognitive health and memory skills
nature.com/articles/s41...

1 month ago 207 53 2 2
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Human eggs must segregate their chromosomes with exquisite precision — yet errors rise with maternal age, causing miscarriage & infertility.
Our new article on @biorxivpreprint.bsky.social shows why chromosome cohesion fails in aging eggs & how to improve it.
www.biorxiv.org/content/10.6... (1/10)

3 months ago 27 15 1 3

Congratulations!

3 months ago 1 0 1 0
Read in Nature: nature.com/articles/s41586-025-09899-8

Read in Nature: nature.com/articles/s41586-025-09899-8

Stress controls epigenetic inheritance!

A histone ubiquitylation-based regulatory hub links stress/environmental signaling to heterochromatin self-propagation and epigenetic inheritance-reshaping how we think about development, drug resistance, and cancer
👉 nature.com/articles/s41586-025-09899-8

3 months ago 36 22 3 4
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Epigenetics Update - Single-nucleus multiomics of murine gonads reveals transcriptional regulatory network underlying supporting lineage differentiation bit.ly/4aPlECl

#Epigenetics #SingleCell #Multiomics #Gonads
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Empower your research with high-res epigenetic insights at epigenometech.com

3 months ago 2 1 0 0
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Extremely excited & proud to share our new preprint - we provide for the first time a single cell map of the mouse brain across sex, the estrous cycle, and peripartum! Data are 🔥 👇

"Single-cell map of the female brain across reproductive transitions"

www.biorxiv.org/content/10.6...

3 months ago 139 60 8 2
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Escape from X inactivation is directly modulated by Xist noncoding RNA Nature Cell Biology - The authors show that increased Xist RNA levels can induce de novo silencing of genes that normally escape X inactivation. SPEN depletion prevents the silencing of escape...

Very happy to share our paper rdcu.be/eUImj out today in @natcellbio.nature.com 🎉🎉🎉
We uncover an unexpected role for endogenous Xist RNA in regulating X-linked genes that escape X-inactivation.

4 months ago 74 31 6 2

Excited to share my first-ever publication, now out in @stemcellreports.bsky.social !! Heartiest congratulations to
Hemant and @barorunumi.bsky.social for jointly leading the work. Grateful to my PI, Srimonta for giving me this opportunity to contribute to this study.
#m6A #X:A_dosage @isscr.org

4 months ago 4 2 0 0

Congratulations Vincent and team!

4 months ago 0 0 0 0
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Thrilled to share that @Avinchal from our lab presented her work on effect of heat-humidity stress on fetal development and #epigenetic regulation in the recent #GordonConference on "Epigenetic Variation: Mechanisms and Impact across Systems" #ClimateChange #GlobalWarming #MaternalChildHealth

5 months ago 1 2 1 0