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Posts by Junjie Guo

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We bid farewell to @yaleneuro.bsky.social graduate Suzhou Yang, who discovered C9orf72 RNA cryptic splicing in ALS-FTD and will soon move to UCLA to start postdoc training with William Yang working on Huntington's disease. Can't wait to hear about your future successes! @yalerna.bsky.social

1 day ago 6 2 1 0
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Thomas A. Steitz Lecture Series by @yalembb.bsky.social

Dr. Rachel Green, “ZAK activation on the colliding ribosome”, hosted by Dr. Yong Xiong

Monday, April 20 | 4:00 PM
📍O.C. Marsh Lecture Hall, Yale Science Building

Open to Yale and affiliated institutions. Details in the flyer below

6 days ago 5 2 0 0

Our work investigating mRNA 3' UTRs that trigger target-directed miRNA degradation is now published! genesdev.cshlp.org/content/earl...

3 weeks ago 19 9 0 0

Agreed but not a Chinese proverb ;)

3 weeks ago 0 0 1 0

Congrats Mike and to the teams for this amazing work!

3 weeks ago 0 0 0 0
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New @yalembb.bsky.social student Han Yin joins the lab for PhD thesis research. Han received his BS in Biology from Peking University @pku1898.bsky.social, where he worked on membrane protein structure, electrophysiology, and of course, RNA. Welcome, Han! @yaleneuro.bsky.social @yalerna.bsky.social

4 weeks ago 5 2 0 0

Our work on the E3 ligase mechanism of target-directed microRNA degradation is now published! Amazing collaboration with Brenda Schulman’s lab led by @jakobfarnung.bsky.social and @elenaslo.bsky.social, with special thanks to @wyppeter.bsky.social, Lianne Blodgett, and Daniel Lin! tinyurl.com/Z8TDMD

1 month ago 59 20 0 0
Post-graduate / Postbac position available | Breslow Lab

We are recruiting a post-bac researcher to join our lab in Yale MCDB! Ideal for a recent college grad looking to get in-depth research experience and mentoring in genetics & cell/molecular biology, working on exciting cilia-related projects. Details: breslowlab.yale.edu/news/post-gr...

1 month ago 1 3 0 0
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Congratulations to The Brain Prize winners Prof. David Ginty (Harvard Medical School, US) and Patrik Ernfors (Karolinska Institutet, SE) for their pioneering work on how the nervous system detects and processes touch and pain:
https://brainprize.org/winners/touch-and-pain-2026

The Brain Prize
HHMI

1 month ago 11 3 0 1
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RNA Club | March 2026

Come support our trainees and engage in discussion across RNA disciplines

📅 Tuesday, March 10
⏰ 9:00 AM
📍 Bass 305, Science Hill

Coffee & bagels provided

Open to Yale and affiliated institutions

1 month ago 3 3 0 0
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Congratulations to Dr. Lianhuan Wei in the lab for winning a poster award at the Gordon conference on FTD and related dementias! @yaleneuro.bsky.social @yalerna.bsky.social

2 months ago 4 1 0 0

Amazing! Congratulations Cate!

2 months ago 1 0 1 0

Congrats Jimmy! You're on a roll!

2 months ago 1 0 0 0

Amazing! Congrats!!

2 months ago 1 0 0 0

Happy Birthday! 🎉

2 months ago 1 0 0 0

That never stopped a certain family in the WH

2 months ago 2 0 0 0
Color photograph of Joan Steitz (Joan Argetsinger Steitz), the distinguished American molecular biologist and biochemist renowned for her groundbreaking discoveries in RNA biology, including the identification of small nuclear ribonucleoproteins (snRNPs) essential to RNA splicing. She is pictured in a close-up portrait within a laboratory or research setting, smiling warmly and directly at the camera with an engaging, approachable expression that conveys enthusiasm and expertise. Steitz has gray hair pulled back, striking blue eyes, and is wearing large, elaborate dangling earrings adorned with purple gemstones and metallic accents. She is dressed in a rich purple blouse. The softly blurred background includes scientific elements such as lab benches, equipment, monitors, charts, and partial signage, evoking the environment of her long career at Yale University where she served as Sterling Professor of Molecular Biophysics and Biochemistry. #JoanSteitz #MolecularBiology #WomenInScience #Biochemistry #RNA

Color photograph of Joan Steitz (Joan Argetsinger Steitz), the distinguished American molecular biologist and biochemist renowned for her groundbreaking discoveries in RNA biology, including the identification of small nuclear ribonucleoproteins (snRNPs) essential to RNA splicing. She is pictured in a close-up portrait within a laboratory or research setting, smiling warmly and directly at the camera with an engaging, approachable expression that conveys enthusiasm and expertise. Steitz has gray hair pulled back, striking blue eyes, and is wearing large, elaborate dangling earrings adorned with purple gemstones and metallic accents. She is dressed in a rich purple blouse. The softly blurred background includes scientific elements such as lab benches, equipment, monitors, charts, and partial signage, evoking the environment of her long career at Yale University where she served as Sterling Professor of Molecular Biophysics and Biochemistry. #JoanSteitz #MolecularBiology #WomenInScience #Biochemistry #RNA

Biochemist/molecular biologist Joan Steitz was born #OTD in 1941.

She (& team) figured out how our cells read/use genetic instructions to make proteins. A key person who helped crack the code on RNA—the molecule that acts like a messenger between DNA & and the proteins our bodies need. #WomenInSTEM

2 months ago 741 172 6 8

Congratulations Cate!

2 months ago 1 0 1 0
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Check our latest collaboration with the Kleaveland Lab (kleavelandlab.org), led by Joanna Stefano and Lara Elcavage: academic.oup.com/nar/article/... (1/2)

3 months ago 15 4 1 1
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Excited to publish our work on how mutations in the muscle-specific ribosomal protein RPL3L drive severe heart disease. This is Part I of a larger body of work led by Michael - stay tuned for Part II on how specialized ribosomes function in normal physiology www.nature.com/articles/s44...

3 months ago 12 3 1 2

Awesome! Congratulations Xuebing!

3 months ago 1 0 0 0
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two men are sitting in a car with the words `` tank is below empty '' above them . ALT: two men are sitting in a car with the words `` tank is below empty '' above them .
5 months ago 1 0 0 0
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The Wu Tsai Institute at Yale University is hiring!

Two faculty searches are now open for neurocomputation and neurodevelopment. If you are at #SfN25, visit booth #3724 to learn more.

wti.yale.edu/opportunities

#KnowTogether #ScienceAtYale

5 months ago 2 1 1 0
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TDP-43 loss brings RNA to a twist ending - Nature Neuroscience In amyotrophic lateral sclerosis (ALS), nuclear depletion and cytoplasmic aggregation of the RNA-binding protein TDP-43 cause widespread dysregulation of mRNA splicing. Two recent studies have now rev...

New article @natneuro.nature.com by @yaleneuro.bsky.social Suzhou Yang & @kavliatyale.bsky.social Postdoc Fellow @zhenlei.bsky.social, highlighting studies by @frattalab.bsky.social Gitler & La Spada labs on the role of TDP-43 on mRNA 3' end in ALS @yalerna.bsky.social www.nature.com/articles/s41...

6 months ago 22 6 0 0
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Oxidative stress sensing by the translation elongation machinery promotes production of detoxifying selenoproteins Selenocysteine, incorporated into polypeptides at recoded termination codons, plays an essential role in redox biology. Using GPX1 and GPX4, selenoenzymes that mitigate oxidative stress, as reporters,...

Colliding ribosomes are potent signals of cellular stress. But do cells use ‘programmed’ ribosome collisions to regulate gene expression? I’m excited to present a new story from my lab led by Frederick Rehfeld(@fred-rehfeld.bsky.social) which revealed that the answer is YES! Read on to find out how👇

6 months ago 78 28 1 6
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mRNA poly(A)-tail length is a battleground for coronavirus–host competition Most eukaryotic mRNAs contain a poly(A) tail, which in post-embryonic cells enhances their stability. Many cytoplasmic RNA viruses also harbor poly(A) tails on their genomic RNA and mRNAs. Here, we re...

Check out the latest work from our lab, led by Arash Latifkar @ara-latifkar.bsky.social , www.biorxiv.org/content/10.1...

6 months ago 31 12 1 2
Poster with QR code linking to the position

Poster with QR code linking to the position

I'm very excited to announce that UNC Biology has 6 faculty positions open this year! The first is for an Asst Professor who studies organismal resilience using an integrative approach 1/n
unc.peopleadmin.com/postings/307...

6 months ago 137 150 5 7
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入我画竹影,入我网蜻蜓。_哔哩哔哩_bilibili -, 视频播放量 1351、弹幕量 0、点赞数 157、投硬币枚数 20、收藏人数 34、转发人数 5, 视频作者 懒云居画, 作者简介 国画|收藏/合作邮箱lanyunjuhua@163.com,相关视频:莫使金樽空对鹤,且放白鹿青崖间,须行即骑访名山。,夏日荷仙走进国画,采荷遇白鹿,国画采莲,乘叶秋游,携鹤伴松风,梦里不知身是鹤,闲云野鹤,春去秋来

Also check out this video from the artist showing the creative process: www.bilibili.com/video/BV1eKK...

6 months ago 2 0 0 0

Excited to see this beautiful art, commissioned from the Chinese artist 懒云居画 (@subaiweipainting on Instagram), on this month's cover of Nature Neuroscience! @natneuro.nature.com @yaleneuro.bsky.social @yalerna.bsky.social @kavliatyale.bsky.social @wutsaiyale.bsky.social

6 months ago 15 2 1 1

Congratulations Sinha lab!

7 months ago 1 0 1 0