... Part of the answer to the problems we now face lies in a better understanding of human beings- how we organize ourselves, how our brains work, and why we are driven to do the things we do. - Tony Pawson. 2/2

All scientists are different but one thing that every successful scientist has in common is an intense, almost obsessive passion to know how things work... 1/2

Multi-tissue multi-omics integration reveals tissue-specific pathways, gene networks and drug candidates for type 1 diabetes - Diabetologia Aims/hypothesis Although genome-wide association studies (GWAS) have identified loci associated with type 1 diabetes, the specific pathways and regulatory networks linking these loci to disease pathol...

link.springer.com/article/10.1... New targets for intervention in T1D

thanks scott! but this means you're gonna have to lecture in the course next year

great! you can tell us what it all means :)

ROMO1 and mitochondrial complex II/SDH are required for spare respiratory capacity and glucose homeostasis in mice - Diabetologia Aims/hypothesis Reactive oxygen species modulator 1 (ROMO1) is a highly conserved inner mitochondrial membrane protein that senses reactive oxygen species and regulates mitochondrial dynamics. ROMO1 i...

link.springer.com/article/10.1... New article from the group on the effects of aging and sex in beta cell glucose sensing - ROMO1 and complex II! Thanks to funders @diabetescanada.bsky.social and CIHR.

thank you for a terrific lecture and discussion - this is always a fun one!

a man in a wetsuit is floating in the ocean with his hand up ALT: a man in a wetsuit is floating in the ocean with his hand up

Today in the 🇨🇦 grad course in islet biology and diabetes we are joined by experts @rlhull-meichle.bsky.social and @teresamastracci.bsky.social for a discussion of context and cues: islets in a sea of acini!

Asked AI to draw an icon to represent the concept of "transplant". Stay in school, AI.

Jess and Quinn on Instagram: "One year ago✨" 1M likes, 4,308 comments - jessandquinn on April 10, 2026: "One year ago✨".

Tell me you've written a CIHR grant without telling me you've written a CIHR grant www.instagram.com/reel/DW9gCDN...

so this is what it's like having a starter go 7 innings #bluejays

A new step toward cures for type 1 diabetes in Canada. Breakthrough T1D Canada has formally asked the federal government to partner in launching the Breakthrough T1D Network for Canada (BTNC), a national effort to accelerate treatments for #T1D. 💙

Learn more 🔗 ow.ly/yi8850YH60L

only blue jay who seems to care rn

Why, John Schneider, why?

new IAPP story from @bruceverchere.bsky.social

Congratulations Karen Maxwell, recipient of the 2026 Peter Gilgan Canada Gairdner Momentum Award.

Full bio: www.gairdner.org/winner/karen...

#2026GairdnerAwards

β-Cell adaptation to #metabolic stresses requires prolactin receptor signaling @apspublications.bsky.social @dream-diabetes.bsky.social journals.physiology.org/doi/full/10....

The #BlueJays have now struck out 47 batters in this series, the most by any team in the first three games of a season in MLB history (since 1900)

Joined today in the 🇨🇦 National Islet and Diabetes grad course by expert Yuval Dor to discuss the etiology of Type 1 Diabetes - viral infection or error of RNA editing?

Beta cell functionality drives response to interventions in T1D from @cevansmo.bsky.social and team

Michael Bishop, Nobel Prize in Physiology or Medicine 1989: Official Lecture YouTube video by Nobel Prize

Very sad to hear of the passing today of our UCSF colleague Mike Bishop at the age of 90. A legendary and inspiring figure. He also led UCSF as Chancellor. Have a listen to his Nobel lecture. youtube.com/watch?v=CDv7...

Terrible umpiring makes us even more excited for ABS.

That is a bad strike three call on Juan Soto in the eighth inning. Shouldn’t happen period. Absolutely cannot happen in a game like this.

That game cannot end like that. A shame.

Gene regulatory networks: from correlative models to causal explanations - Nature Reviews Genetics In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without compromising explanatory power.

Sorting out the hairballs www.nature.com/articles/s41...

Incretin receptor masterclass today in the 🇨🇦 National Graduate Course in #islet biology and #diabetes from experts @daveyboyhod.bsky.social and @danieljdrucker.bsky.social from cell biology to translational impact #GLP1R #GIPR

FORZA ITALIA

Progress in science depends on new techniques, new discoveries, and new ideas, probably in that order.

- Sydney Brenner

the latest on AI:

1. Language models are optimized for coherence, not truth

The core objective during training is to produce text that is likely and coherent given the context. That objective does not directly encode a concept of factual truth. As a result, the system can produce [garbage]...