Big thanks to PTEN Research Foundation, co-authors, editorial team & reviewers; @grauperalab.bsky.social @carrerasijc.bsky.social @sjdhospitalbarcelona.org

We’re happy 😄 to share our latest work in Cancer Discov @theaacr.bsky.social – we discover that PTEN UPD 🧬 in endothelial cells causes vascular malformations in PTEN Hamartoma Tumor Syndrome (PHTS), create a new mouse model 🐀 & test PI3K signaling inhibitors 💊.

aacrjournals.org/cancerdiscov...

Context-dependent response of endothelial cells to PIK3CA mutation Cancer mutations in the PIK3CA gene cause congenital disorders. The endothelium is among the most frequently affected tissues in these disorders, displaying aberrant vascular overgrowth in the form of...

We are excited to share our work on Context-dependent response of endothelial cells to PIK3CA mutation. A tour the force of many; thank you all for your invaluable contribution. @aangulou.bsky.social @ruibenedito.bsky.social @debocklab.bsky.social @sandradcastillo.bsky.social
bit.ly/4blKSqa

🔬 ¡Buscamos Técnico/a de laboratorio!
📋 Mantenimiento de colonia, procesamiento de muestras y más.
📍 Barcelona
📩+info: hospitalsantjoandedeu.talentclue.com/es/node/1129...

Please RT!

🙋🏻‍♀️

Gate2Brain Receives EMA Orphan Drug Designation for Its Pediatric Cancer Treatment The IRB Barcelona spin-off Gate2Brain, a cutting-edge technology platform focused on enhancing drug delivery to the brain, has reached a major milestone in the fight against pediatric brain tumors by ...

📰 #IRBBarcelona spin-off #Gate2Brain receives European Medicines Agency (EMA) Orphan Drug Designation for its #PediatricCancer treatment.

🗣️Meritxell Teixidó (CEO): "We are moving toward clinical trials that could transform the treatment of pediatric brain tumors".

➡️ bit.ly/4fLmnEb

#Innovation

🧪

Our latest paper reveals an intriguing and essential role for the class III #PI3K VPS34 in Treg homeostasis and function. Selective deletion of VPS34 in Treg led to a scurfy-like phenotype, suggesting an essential role for VPS34 in Treg-suppression.
doi.org/10.3389/fimm...
#immunosky

Hi!

I just compiled some of the new Barcelona cancer labs! Many more missing, so let me know if anyone needs to be added!

go.bsky.app/AkCGugm

PIPgenerating ART: Where Art meet Science YouTube video by PIPgen

The freshly cooked video summarizing the Art project developed in the frame of our PIPgen MSCA DN: “PIPgenerating ART: Where Art meet Science “. A collaborative activitys between our students and the Cambridge School of Visual Performing Arts.
www.youtube.com/watch?v=tQxA...