Managing Blood Pressure in Dialysis Patients: A Summary of UK Clinical Practice Guideline

www.sciencedirect.com/science/arti...

The Effect of SGLT2 Inhibitors on Blood Pressure in Relation to Baseline Kidney Function: A Systematic Literature Review and Data Analysis AbstractBACKGROUND. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce both systolic blood pressure (SBP) and diastolic blood pressure (DBP). The gl

The Effect of SGLT2 Inhibitors aka #Flozins on Blood Pressure in Relation to Baseline Kidney Function: A Systematic Literature Review and Data Analysis

🔗 academic.oup.com/ajh/article-... 🔒

I am delighted to see that @ukkidney.org has made the right call and exited X/Twitter.

Happy to contribute to this important statement
@ahascience.bsky.social on cuffless devices led by @jordybc.bsky.social !

Cuffless Devices for the Measurement of Blood Pressure: A Scientific Statement From the American Heart Association | Hypertension ahajournals.org/doi/10.1161/...

The majority of doctors supported the recent strike. So why did the Department of Health suggest the opposite? | Peter Kellner It would seem that poll data was cherrypicked and then used to brief the Times. Such distortion of facts from a public body should alarm us all, says former president of YouGov Peter Kellner

The majority of doctors supported the recent strike. So why did the Department of Health suggest the opposite?

www.theguardian.com/commentisfre...

Don’t believe Nigel Farage’s denials. He targeted me for being Jewish – and it hurt | Peter Ettedgui Now that my former classmate has finally spoken about the allegations of his behaviour at school, I feel compelled to address his points directly, says Peter Ettedgui, a film director and producer

www.theguardian.com/commentisfre...

CDC website altered to reflect RFK Jr’s belief in link between vaccines and autism Public health and autism specialists roundly condemn alteration to the ‘vaccine safety’ webpage

www.theguardian.com/us-news/2025...

WTAF?

The BMA and other trade unions stand together against anti-migrant rhetoric

The announcement of new asylum measures by the Home Secretary risks fuelling anti-migrant rhetoric.

We reiterate our solidarity with our colleagues, many of whom are being subjected to increasingly hostile treatment as a direct result.

www.bma.org.uk/news-and-opi...

Paying my respects to Mani this evening 😢

It could be worse John - at least there’s a handrail.

Yep. I’ve also seen it a fair few times with spiro - on occasions <125 mmol/L.

Paired osmolalities in a couple of stable pts w mild hyponatraemia on spiro suggest it’s due to increased ADH.

Our research recommendations ….

Should we have included an RCT or intensive vs. relaxed BP goal in dialysis patients?

If yes, what BP measurement and what BP goals? What about patients on PD?

BID study provides some insights into how challenging this could be to deliver!

Our @ukkidney.org guidelines here in BMC Nephrology. 💯% agree that in-unit BP should ONLY be used for determining safety of individual HD sessions and NOT long-term CV risk modification. But changing practice will be a long haul.

link.springer.com/epdf/10.1186...

Great blog!

Management of blood pressure in adults, children and young people on dialysis: UK kidney association clinical practice guideline - BMC Nephrology People with end stage kidney disease receiving dialysis have a very risk of cardiovascular disease and mortality. Hypertension is a modifiable risk factor for cardiovascular disease and mortality, affecting around 90% of dialysis patients. Conversely, intradialytic hypotension in haemodialysis patients is associated with debilitating symptoms as well as the risk of cardiovascular disease and mortality. Blood pressure management in dialysis patients involves accurate measurement of blood pressure, setting a target blood pressure, adequate fluid volume management, lifestyle changes, modification of dialysis and dialysate, and the use of medication with proven efficacy in these patients. However, globally there is no published contemporary clinical practice guideline to assist health care professionals to manage blood pressure in dialysis patients. This is mainly because of a dearth of good quality evidence to inform guideline recommendations. Here, we present a comprehensive guideline to manage blood pressure in dialysis patients based on a thorough systematic review of literature. The guideline development committee comprised a multidisciplinary group of nephrology healthcare professionals and a patient. The evidence underpinning the guidance is often of moderate to low quality, influencing the strength of the recommendations. Therefore, the committee have come up with a list of research recommendations with a view to informing future guidelines. It is envisaged that this guideline will improve the care and outcomes of dialysis patients in the UK and elsewhere.

@ukkidney.org guidelines for managing blood pressure in adults and CYP on dialysis is now published in BMC Nephrology 👏🏻

@profdg.bsky.social @hswapnil.medsky.social

Find it here: link.springer.com/article/10.1...

With Nye Bevan in Cardiff today

Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE): an international, parallel-group, randomised controlled trial Patients undergoing maintenance dialysis for kidney failure are at substantial risk of cardiovascular morbidity and mortality. We aimed to establish i…

Proud to have worked with colleagues and friends around the world on #ACHIEVE. We're disappointed spiro didn't prevent CV death/heart failure hospitalizations, but we've shown it's possible to do publicly funded large RCTs of repurposed meds in ESKD. More to do!
www.sciencedirect.com/science/arti...

Britain is ‘a terrible place’ to sell medicines, says drug firm executive Sanofi’s market access chief urges ministers to come up with a roadmap to raise spending on new treatments

www.theguardian.com/business/202...

From someone who has been PI on multiple clinical trials in people with kidney disease this is deeply concerning …

@rthonwesstreeting.bsky.social

Morrissey puts his business interests in the Smiths up for sale ‘to any interested party’ Musician says he has ‘no choice’ after being ‘burnt out by any and all connections’ to his former bandmates

Unlike Radiohead it doesn’t look like the Smiths will be touring again anytime soon 😢

www.theguardian.com/music/2025/s...

bihs.org.uk/news/21/prof...

Graham was my boss and MD supervisor at St George’s, University of London.

He started me on a journey that continues to this day. Our East Kent Hypertension Clinic is part of Graham’s legacy.

A giant in nephrology and CV medicine 🙏🏻

18km continuous ascent to Col de la Colombière with my mate Bryan over the summer 🥵

Aleppo by Jenny Saville

Poole Harbour

Rethinking approaches to analysis of global randomised controlled trials Choice of statistical models and data integrity are vital A BMJ investigation by Doshi (doi:10.1136/bmj.r1201)1raises concerns about the integrity of two randomised trials with surrogate endpoints th...

Nephrology community take note 👇 #nephsky @bmj.com

Risks of assuming homogenous effects of ancillary treatment in heterogenous healthcare systems in global RCTs

www.bmj.com/content/389/...

Excellent CPD - thanks Swap 👍🏻

Getting Away With It All
James
#IOW2025
❤️

… with Prof Steven Powis nephrologist and NHSE med director asking whether we are ready for the proliferation of new treatments in GN? Bring it on! 💪🏻 @ukkidney.org #UKKW25 2/2

@ukkidney.org #UKKW25 Prof David Wheeler and one of my fave slides reminding us how nephrologists weren’t so good at RCTs 🤣 but how times have changed … 1/2

💪 PD lets patients manage care at home, maintaining hope as they wait.

👥 We honor recipients, donors, and all who navigate this path with strength. PD supports this journey.

#WorldTransplantDay #PeritonealDialysis #TransplantDay

🌱 Today is #TransplantDay, celebrating organ donors' life-saving gift. At ISPD, we emphasize the journey before that crucial call.

🫘 #PeritonealDialysis (PD) is more than a treatment; it's a vital bridge offering freedom and quality of life for those awaiting a transplant.

#WorldTransplantDay