☕ @joshifrenster.bsky.social @amartinezarias.bsky.social & co utilize mosaic mouse #gastruloids as a model of cell fitness & competition, identifying a temporal window between primed pluripotency and early gastrulation during which #CellCompetition occurs in mammalian #embryogenesis.
bit.ly/4cBmfGK
We moved to the UK from US when my daughter was 3. MenB vaccine is not given to children in the US so my daughter missed it and they don't want to give it to her now despite me requesting it (she is 7 now) and we were told to go private if we want it
Well. This will provoke some discussion. Given that MRC was actively recruiting new board members 6 months ago, boards which all have now been abolished, I am worried about the amount of thought that has gone into this new approach, that marks a sea-change in funding. So many questions...
Job alert: open position for a Professor or Associate Professor of Computational Genomics in Health and Disease at University College London.
Based in the Department of Genetics, Evolution and Environment of UCL, and UGI, and funded by the UCL Health Strategy.
www.ucl.ac.uk/work-at-ucl/... 🧪
Another update from #UKRI CEO on #UKsciencefunding #UKRI
www.ukri.org/news/ukri-ce...
No new information and fails to address/explain the severe funding rate cuts taking place at MRC for the round currently under review (Sept2025). That's 2025/26 budget so should *not* be affected by SR.
Congrats
Congrats
This week, two of our PhD students successfully passed their PhD VIVA! Congratulations Dr. Zoe Mitchell and Dr. Martina Demurtas! We are so proud of you both!
Yes. Intelligenza Artificiale in Italian.
We are in EMBO J. See DNA and non-octameric nucleosome-like particles in situ
link.springer.com/article/10.1...
Sorry to hear!
My goodness 😞
So now we have it- not only the reduction from 12-13 to 3 grants from each board recommended for funding but the budget for applicant-led research to be reduced from £200 million to £113 million per year. This is appalling, Especially given all that is happening with medical research in the US.
I watched much of Ian Chapman's (Head of @ukri.org) appearance this morning at @ukparliament.parliament.uk Science, Innovation and Technology Committee..
A few points and new information that bioscientists may find interesting...
A 🧵
Leaks everywhere and finally we get an official statement, one that somehow manages to say a lot while; No timelines. No clarity. No acknowledgement of impact on ECRs whose careers depend UKRI funding.
“Later this year” isn’t a plan. And the sector deserves better than reassurance without detail.
I worry this is going to kill a lot of careers. Mine being one of them.
But beyond the selfish...there's going to be a whole generation of scientists who are not going to be able to support their careers, this is going to affect UK research in a big way...
1 budget for 26-30 is rising 🎉
2 quota for basic research stable 🙂
BUT
3 we're slashing success rate for currently assessed grants 🫠
4 next call hopefully in Apri 2027 (with £s for lucky few going out months later, suppose) 💀
How does this make us more competitive?
www.ukri.org/news/open-le...
Today, we're sharing an open letter from our Chief Executive, Professor Sir Ian Chapman, outlining changes to UKRI investment approach, and addressing concerns about research funding and the financial position of STFC. Read his letter here: www.ukri.org/news/open-le...
This UKRI situation is batshit insane.
Congrats Miguel and team, nice to see this out!
New preprint from the lab! We dig into the regulatory roles of TEs in the mouse placenta, with some surprising findings. Led by the awesome @smamante.bsky.social. Particular kudos to him for navigating the many twists and turns of the project.
Congrats Pradeep and team!
Check out our new findings showing BRD4's role in preventing the premature activation of developmental transcription factors via #Polycomb, providing new mechanistic insights into the pathogenesis of neurodevelopmental disorder #CdLS #NDDs, #chromatinopathies www.biorxiv.org/content/10.6...
Academics vying for a spot in Epstein‘s world. There are so many. I feel the need to make a thread, so I don’t keep confusing them. 1/
New NIH funding strategy has been formalized.
I really do hope scientists understand what this means for the future of science (funding) - it's not subtle.
www.niaid.nih.gov/about/unifie...
New goal for life: being able to play this (well not this good) even if it takes 20 years of practice
www.youtube.com/watch?v=wj1x...
I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good.
Stay free
UKRI pauses several funding calls amid priorities shake-up www.researchprofessional.com/news-article...
No need to be!
Happy to share with you our work on how the interferon response impacts embryonic development 🦠Mammalian embryos contain endogenous dsRNAs that resemble viruses and can be misrecognised by the dsRNA sensor MDA5.
Thanks to all collaborators, we could not have done it without you 🤩
rdcu.be/eWMfA
Asti :)
