Entering our neuro ICU. Someone needs to update this photo.

Remember all the talk of healthy young people dying suddenly after COVID-19 vaccination?

Our new study in @plosmedicine.org shows there's absolutely nothing to that.

journals.plos.org/plosmedicine...

A medical journal says the case reports it has published for 25 years are, in fact, fiction A Canadian journal has issued corrections on 138 case reports it published over the last 25 years to add a disclaimer: The cases described are fictional. Paediatrics & Child Health, the journal…

wait wait WHAT? Apparently a "medical journal" in canada has been publishing fictionalized case reports for decades without indicating to its readers that they were fictionalized... retractionwatch.com/2026/03/03/c...

Here’s the New Yorker story that started this ball rolling bsky.app/profile/newy...

It’s no wonder people distrust science.

Let's see if @oxfordunipress.bsky.social and the Canadian Paediatrics Society do the right thing and retract this fabricated report.

cc: @publicationethics.bsky.social

Among these? The most detailed report of neonatal opioid toxicity from breastfeeding ever published.

One small problem: It's pharmacologically impossible.

The official journal of the Canadian Paediatric Society has just acknowledged that more than 100 of its case reports are fabricated. Incredible reporting from @retractionwatch.com retractionwatch.com/2026/03/03/c...

Did a Celebrated Researcher Obscure a Baby’s Poisoning? After a newborn died of opioid poisoning, a new branch of pediatrics came into being. But the evidence doesn’t add up.

Did a Celebrated Researcher Obscure a Baby’s Poisoning?

He sure did.

www.newyorker.com/magazine/202...

Why is a 20-year-old study "still under fire"?

Because:

- it was wrong
- the lead author lied to conceal it
- millions of women and infants were harmed
- other death investigations were misled
- when shown this, major institutions looked away

www.cbc.ca/news/health/...

This story is jaw dropping: one very bad actor, but also scientific journals (the Lancet!), a medical examiner, a hospital, & other establishment pillars who were taken in & now refuse to correct the record. Victims include not just baby who died but others removed from parents based on bad science.

For nearly 20 years, breastfeeding women have been cautioned against codeine, based largely on a single case report. The Lancet has now issued an Expression of Concern about that paper.

Oh, it *will* make noise

Absolutely wild story even for those of us who know the context of Motherisk (!)

This story is so wild and so well told. I woke my husband up gasping at the "we made it up" part.

I’ve spent 15 years challenging a flawed explanation for an infant’s death. Credit to The New Yorker for patient investigative journalism that corrected the record when institutions did not.

New rule: If you order the D-Dimer, you have to interpret the D-Dimer

For those contemplating a detox or cleanse in the new year, here’s a toxicologist’s explanation of how they work:

They don't.

We've all seen firsthand how well opioids can work when first given. But they are at their pharmacologic best in the initial days of treatment.

Continue them for weeks, months, or years and the calculus becomes progressively less favourable.

Opioid prescribing in Canada: a continued retreat from God’s own medicine [See related article at www.cmaj.ca/lookup/doi/10.1503/cmaj.250670][1] Key points In this issue’s research article, Rebić and colleagues show that rates of opioid prescribing across 6 Canadian provin...

Canadian MDs are relying less on opioids. That is a good thing. New commentary from me in @cmaj.ca

www.cmaj.ca/content/197/...

PSA: When a naturopath recommends chelation “to remove the metal from your body,” that is exactly what you should not do.

Join us for UofT Therapeutics Day November 1st

- drug interactions
- NSAID allergy
- within-class safety differences
- complex polypharmacy
- pharmacogenetics
- SGLT2 inhibitors
- buprenorphine

Register here: eventbrite.com/e/the-drugs-we…

Funded Research - PSI Foundation List of projects funded by PSI Foundation.

Drs. Jessica Kent ‪Rice @jessicakentrice.bsky.social ‬& David Juurlink @davidjuurlink.bsky.social study on trends in opioid agonist therapy retention after non-fatal #OpioidOverdose: www.psifoundation.org/funded-resea... #InternationalOverdoseAwarenessDay #IOAD2025 @sunnybrookhsc.bsky.social

Toronto-area MDs and pharmacists: Join us for Therapeutics Day 2025

- Relevant topics
- Great speakers (but also me)
- You will be fed
- You will get CE credits

Register here: tinyurl.com/mr447y5n

I'm not saying these "ivermectin cured my cancer" testimonials are entirely fabricated but THEORETICALLY if someone:

1) no longer had a medical license, and
2) profited from pushing ivermectin, and
3) had no qualms about lying to desperate people ...

Just putting this out there

Dr. David Juurlink: Relieving pain in the era of fentanyl YouTube video by Therapeutics Initiative

🚨 ICYMI - #Opioids prescribing webinar recording featuring pharmacologist @davidjuurlink.bsky.social 🚨

💊 What have we learned about #prescribing?
💊 How should we treat pain when opioids overdoses have become an intractable epidemic?
👉🏽 ti.ubc.ca/juurlink-ana...

#pain #MedEd #medsafety

Every time I hear someone mention tramadol

To sum up:

- Carbapenems lower VPA concentrations abruptly and dramatically

- They do this by tinkering with VPA metabolism

- Consider carbapenems in patients with severe VPA toxicity and those you expect to develop it

/end

In the second group, I start mero or erta early

It's conceptually similar to early alkalinization for ASA toxicity

/12

The second is people *expected* to get sick, generally those who ingest >300-400 mg/kg

/11

The first is easy: the sickest of the sick

If you're contemplating hemo, you should be contemplating mero or erta

As I wrote:

/10