New in Nature Protocols buff.ly/DUCGVAf
A standardised method for reproducible tracking of gut bacteria via the SIHUMI microbial community.
Congrats to APC researchers Natalia Rรญos Colombo, Mariana Perez-Ibarreche, P.Ross & C.Hill, in collab with Pranav Lanka at @tyndallinstitute.bsky.social
Posts by David Hourigan
New APC paper in Molecular Nutrition & Food Research.
First author Felipe Miceli de Farias & colleagues identifed a new circular bacteriocin from Streptococcus. The study is part of the research of Prof. Paul Ross's group at APC.
onlinelibrary.wiley.com/doi/10.1002/...
#Bacteriocins #UCC #Teagasc
We previously engineered Saccharomyces cerevisiae through CRISPR-Cas9 integration to produce Ply511, a bacteriophage endolysin active against L. monocytogenes, showing the potential of engineered yeast to produce endolysins for biocontrol. In this study, we extended this approach to the probiotic yeast S. boulardii and directly compared the two yeasts as secretion hosts for Ply511. Using a simulated human gastrointestinal environment, we evaluated their ability to retain endolysin activity and reduce L. monocytogenes levels.
New paper from the CEB- @uminho.bsky.social & APC
๐๐ฏ๐๐ฅ๐ฎ๐๐ญ๐ข๐จ๐ง ๐จ๐ ๐ญ๐ก๐ ๐๐๐ฅ๐ข๐ฏ๐๐ซ๐ฒ ๐จ๐ ๐๐ง ๐๐ง๐ญ๐ข-๐๐ข๐ฌ๐ญ๐๐ซ๐ข๐ ๐๐ง๐๐จ๐ฅ๐ฒ๐ฌ๐ข๐ง ๐ฏ๐ข๐ ๐๐๐๐๐๐-๐๐๐ฌ๐ ๐๐ง๐ ๐ข๐ง๐๐๐ซ๐๐ ๐ฉ๐ซ๐จ๐๐ข๐จ๐ญ๐ข๐ ๐บ๐๐๐๐๐๐๐๐๐๐๐๐ ๐๐๐๐๐๐๐
๐๐
Appl Microbiol Biotechnol buff.ly/pDDfR3f
#CRISPRCas9
@ellen-murr.bsky.social @rioscolombo.bsky.social @colinhillucc.bsky.social
Diarmuid OโBrien, CEO of Research Ireland; Dr Paddy Austin, Assistant Director for ERDF, Northern and Western Regional Assembly; Professor Garry Duffy, Director of ARC Hub for HealthTech, University of Galway and RCSI; Professor David Burn, President of University of Galway; Elena Panteva, Directorate General for Regionalโฏ&โฏUrban Policy, European Commission.
The new ARC Hub for HealthTech was officially launched today at @uniofgalway.bsky.social. The Hub will drive the development of solutions to improve chronic disease management. Read more: www.researchireland.ie/news/arc-hub... #EUInMyRegion @atu-ie.bsky.social @rcsi.bsky.social
Very cool paper www.nature.com/articles/s43...
The authors found that FMTs from *older* mice into adult females improved ovarian function and lowered inflammation.
FMTs from younger mice into adult mice led to higher inflammation and *reduced* ovarian function in older mice.
SFA Talks from @Kristinacampbell, Sean Gibbons, and Howard Bauchner offered invaluable wisdom on science communication, career development, and strategies for publishing in high-impact journals! ๐ #ISAPP2025
This year marked my first @isappscience.bsky.social annual meeting as part of the @isappsfa.bsky.social executive committee (Communications)
Brilliant science, thoughtful discussion, and great company throughout.
A huge thank you to my fellow committee members, Iโm already excited for next year!
๐ซถ๐ผ
#ISAPP2025 Afternoon sessions underway with talks from Haruki Kitazawa, Guy Vergeres and Maria Marco! ๐ค
@isappscience.bsky.social
Day 3 of #ISAPP2025 begins with IAC selected talks from Maria Rodriguez-Palmero Seuma(Effects of a probiotic formula on symptoms and quality of life in peri- and postmenopausal women) & Elaine Vaughan(Towards EU health claims for prebiotics: A focus on scientific evidence and regulatory pathways)๐
SFA highlight talks from Valentina Cattero (Prebiotic-like activity of cranberry extract: Modulating gut microbiota composition and enhancing intestinal barrier function in ex vivo and in vivo models) & Kait Al (Acetate and the gut-brain axis: A pilot study on mental health and metabolic outcomes)๐
A huge congratulations to our ISAPP SFA Poster Winners for 2025! We are delighted to present Benjamin Levine and Caroline Dricot with their awards ๐๐
#ISAPP2025
@isappscience.bsky.social
โจSFA Membershipโจ
To join/renew your membership, fill out our registration form (there's no fee to join).
isapp-sfa.com/member-regis...
SFA Membership allows you to connect with an amazing network of ECRs, keep up to date on SFA blogs & events and the opportunity to attend our annual meetings!๐
This month's ISAPP-SFA blog by Brendan Daisley presents theย R package,ย isolateR, designed to meet the high-throughput demands of modern microbial isolation workflows!ย ๐ฌ
๐ www.isapp-sfa.com/new-blog/202...
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Mobile genetic elements: the hidden puppet masters underlying infant gut microbiome assembly?
-in Microbiome Research Reports by @kkreuze.bsky.social @frimanscience.bsky.social and Tommi Vatanen
www.oaepublish.com/articles/mrr...
Discovery and synthesis of leaderless bacteriocins from the Actinomycetota
journals.asm.org/doi/10.1128/...