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Posts by Patrick Bradley

So sorry to hear this Becky -- thinking of you and your family!

4 weeks ago 1 1 0 0

Anaerobic riboflavin degradation by human gut Lachnospiraceae www.biorxiv.org/content/10.64898/2026.02...

2 months ago 3 2 0 0
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In remembrance of Peer Bork  | EMBL EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.

very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...

3 months ago 146 82 10 7

Extremely belated as this is the first time I've signed in in a while, but thank you so much Daan for doing this! Really opens up a lot of phylogenetic analyses that can be done with this cool new database.

3 months ago 2 0 0 0
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Adaptive adjustment of profile HMM significance thresholds improves functional and metabolic insights into microbial genomes AbstractMotivation. Gene function annotation in microbial genomes and metagenomes is a fundamental in silico first step toward understanding metabolic pote

I really enjoyed reading this paper.(1/3)

Adaptive adjustment of profile HMM significance thresholds improves functional and metabolic insights into microbial genomes
doi.org/10.1093/bioa...
#MicroSky

1 year ago 14 4 1 0

Posting the first section of the ASM bylaws below. The last line says that they are committed to promoting inclusive diversity with equity access and

1 year ago 53 18 1 1
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A phylogenetic approach to comparative genomics Nature Reviews Genetics, Published online: 08 January 2025; doi:10.1038/s41576-024-00803-0Controlling for phylogeny is essential in comparative genomics studies, because species, genomes and genes are not independent data points within statistical tests.…

NEW ONLINE! New online! A phylogenetic approach to comparative genomics

1 year ago 19 11 0 0
A screenshot of a paper on bioarxiv illustrating the lack of blue sky share button!

A screenshot of a paper on bioarxiv illustrating the lack of blue sky share button!

Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!

1 year ago 384 196 9 6
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gcplyr: an R package for microbial growth curve data analysis - BMC Bioinformatics Background Characterization of microbial growth is of both fundamental and applied interest. Modern platforms can automate collection of high-throughput microbial growth curves, necessitating the deve...

Glad to see this out! gcplyr is an R package that makes it easy to wrangle and analyze microbial growth curve data. In the paper, I highlight what it adds compared to other software

(a new version is up too! update to get the latest features)

#microbiomesky #MicroSky 🧬🖥️🦠🔬

doi.org/10.1186/s128...

1 year ago 25 17 0 0
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Here we describe the nitty gritty behind our toolkit assembly for screening pooled genetic tools to identify those that work for non-model bacteria. Made available through @addgene.bsky.social:
www.addgene.org/kits/cultiva...

2 years ago 21 8 1 0

#NSURP2024 share broadly 😀

2 years ago 2 11 0 0
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Dynamics of bacterial recombination in the human gut microbiome Recombination is a ubiquitous force in bacterial evolution, but its dynamics are poorly characterized in many natural populations. This study presents a metagenomic approach for quantifying the landsc...

Excited (and relieved!) to share that my 1st paper in grad school finally came out in PLOS Biology! We were motivated by a very basic question: how fast, really, do bacteria exchange DNA in the human gut? (1/n)

2 years ago 76 31 3 4

My favorite story from the Staph GRC last summer, from Tamia Harris-Tyron's group, is now up on biorxiv.

Testosterone activates agr pathway (quorum sensing pathway that activates virulence factors) in S aureus!

2 years ago 9 6 1 0

"My husband thought that your room is very empty, so you might like a little weasel" still pops into my brain periodically

2 years ago 1 0 0 0

oh my god, it's soooo good

2 years ago 3 0 4 0

Pleased that grad student Jacob Baker's tour de force analysis of intraspecies dynamics in the skin microbiome -- including >4,000 isolates of 2 species from 8 families carefully clustered into lineages and analyzed is now up.

2 years ago 52 25 2 1
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please please tell your friends and loved ones about test2treat.org — a completely free site. they offer free tests, and FREE TREATMENT. no insurance needed. literally did not enter any insurance or payment info and i got a paxlovid script in an hour. please share.

huge h/t to @eboldy.bsky.social ♥️

2 years ago 1219 1133 10 21
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Six weeks left until the abstract deadline for Biology of Genomes at CSHL #BoG24! We have a stellar lineup of keynotes and discussion leaders (=~invited speakers), and look forward to another brilliant meeting in May 7-11. Abstract submission & info:
meetings.cshl.edu/meetings.asp...

2 years ago 13 17 2 0

for folks in grad programs, what are key barriers that may affect your ability to regularly attend seminars organized as part of routine department seminar series?

2 years ago 3 6 2 0
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Our department is recruiting a tenure-track Assistant Professor on microbial interactions linked to the
NCCR Microbiomes nccr-microbiomes.ch Don't miss this opportunity to join a friendly, dynamic department in a city with hard-to-beat quality of life. Apply tinyurl.com/4k2mevax by Jan 31!

2 years ago 66 64 1 0
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We are delighted to share our work on “Inference of the demographic histories and selective effects of human gut commensal microbiota over the course of human history”! www.biorxiv.org/content/10.1... Please check out the full tweet thread and GIF here: twitter.com/nanditagarud...

2 years ago 15 10 2 0

New PI slack was an incredible and often sanity saving resource for me in the early days, and still great now. I encourage New PIs to join!

2 years ago 13 4 0 0

For microbiologists seeking faculty jobs: Rutgers has 4+ faculty searches in microbiology right now! Please share widely and see below for details and links on the individual positions 1/5

2 years ago 29 57 1 3
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We're hiring in computational biology!

UW Genome Sciences has been a stellar place to start a computational lab - fantastic students, colleagues, and opportunities for collaboration with cutting-edge experimentalists and clinicians. Seattle is a great place to live too.

Please circulate our ad!

2 years ago 71 86 2 2
Department of Microbiology at UMass Amherst

Come work with us in Microbiology at UMass Amherst! We're hiring a microbial immunologist. More info here -->
careers.umass.edu/amherst/en-u...

Apply by the November 13, 2023 to ensure consideration! Learn more about us here: www.micro.umass.edu
#microsky #jobs 🧪🦠🧫

2 years ago 34 59 2 1
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Faculty position opening at Université de Montréal 👇🏾

Assistant or Associate Professor position in Bacteriology in the Department Microbiology, Infectious diseases & Immunology.

Please share!

2 years ago 21 25 0 1

The Molecular Microbiology department at Washington University in St Louis School of Medicine is recruiting at the Assistant Professor level! Come be a #newPI with me in this stellar research environment and fantastic microbiology community. facultyopportunities.wustl.edu/apply/Postin...

2 years ago 16 29 0 1

I am looking for a graduate student and a postdoc to join my group! We are a computational group working on understanding evolution in natural populations with a large emphasis on the microbiome. Please get in touch by dm or email! garud.eeb.ucla.edu

2 years ago 53 76 0 3
schematic of code used to move between different Bioconductor containers supported by tidyomics

schematic of code used to move between different Bioconductor containers supported by tidyomics

schematic of how common grammar can be applied to different Bioconductor data objects

schematic of how common grammar can be applied to different Bioconductor data objects

This preprint describes tidyomics, a community-led effort to enable application of grammar from tidyverse to omics data in Bioconductor. I've been greatly impressed with the crowd-sourcing of issues via GitHub Projects.

preprint: www.biorxiv.org/content/10.1...

github: github.com/tidyomics

2 years ago 86 34 3 4
University of Massachusetts Chan Medical School, Program in Bioinformatics and Integrative Biology Full service online faculty recruitment and application management system for academic institutions worldwide. We offer unique solutions tailored for academic communities.

2nd Bluesky post … faculty search! Genomics and Comp Bio dept @ UMass Chan Med School academicjobsonline.org/ajo/jobs/25641 pop genomics, imaging, stat. genetics, machine learning aka cool science w big data.

Collab & supportive environment where you can innovate & make discoveries. Join us!

2 years ago 45 59 2 1