Happy to share that my review "Clues for glues: from serendipity to nature's blueprints in degrader discovery" is now out: doi.org/10.1042/EBC2...

The field is moving fast, and there’s no shortage of open questions - what a great time to be thinking about where #molecularglues and #TPD go next!

Welcome! You are invited to join a webinar: Dana-Farber Targeted Protein Degradation Webinar Series. After registering, you will receive a confirmation email about joining the webinar. Bi-weekly Seminars exploring different mechanisms of small molecule mediated protein degradation for the development of chemical probes and/or drugs. The Webinar Series will take place bi-weekly on: T...

Free registration for the biweekly DFCI #TPD webinar series: bit.ly/3OmMRjp

Very excited for our next seminar this Thursday, March 20th:
Martin Schwalm (@thesgc.bsky.social, formerly Knapp lab) will share insights on UPS inhibitors and Dean Clift (TRIMTECH Tx) will discuss hijacking TRIM21 for protein #degradation!

👉Join us at 12 PM EST/ 5 pm CET (‼️ US/EU time mismatch ‼️)

Very grateful also to RGCC International for recognising my work with the Cancer Drug Discovery Research Award 2025 and many congratulations to all other awardees!

Special thanks to Christoph Philipp Sager, Fides Benfatti, @ninahartrampf.bsky.social, and Dennis Gillingham for organising the inspiring event and for putting together a great social program featuring some late-night #alchemy 🧪 and a guided tour of Fondation Beyeler

Hugely excited to have participated in the #DMCCB Basel Symposium at @biozentrum.unibas.ch last week. Such a privilege to spend two days discussing drugging challenging targets while getting to know the Swiss Medicinal Chemistry and Chemical Biology chapter of the @swisschemistry.bsky.social

Join us for the final TPD webinar of 2024 on 12/19.

@fleurmferguson.bsky.social & Eric Wang - "ZBTB11 Degraders Target Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC"

Slava Ziegler - "Targeting IDO1 by monovalent degraders exploiting the native IDO1 degradation mechanism"

The Proximity Collective: TPD enthusiasts Join the conversation

We have one but missing representation for many of the TACs :) go.bsky.app/FreGFDW

It seems no starter pack exists yet for the migrated #TPD community - here is an attempt at one: go.bsky.app/FreGFDW

Hi Bluesky! New here and a bit surprised not to see a starter pack dedicated to Chemical Biology so.. here we go!
go.bsky.app/DDpDuvo

Women in chemistry starter pack here: go.bsky.app/LjumNEg
#ChemSky
please repost :D

#ChemSky #realtimechem #FluorescenceFriday

Let’s start the week an updated starter pack for ubiquitin and Ubl signalling, biology, and mechanisms. More than 40 profiles to follow.

go.bsky.app/3VPQofn