A navy blue social card that reads 'Academy of Medical Sciences backs early career researchers' in white text. Pictured from left to right is Dr Paraskevi (Pari) Kritsiligkou and Dr Hayley Lavender.

Springboard success! Congratulations to Dr Pari Kritsiligkou (@parikki.bsky.social) and Dr Hayley Lavender, both recipients of prestigious Springboard Awards by the Academy of Medical Sciences.

🔗 bit.ly/4swbfk9

#TeamLivUni

Academy of Medical Sciences backs 55 early career researchers with £6.7m for discovery-driven health research

Delighted and honoured to receive the @acmedsci.bsky.social springboard award this year to develop my research! 🥹
I am thankful to all mentors and colleagues, and I am looking forward to expanding my research team! A position will be available soon 🎉 #springboard26

bit.ly/427CuXc

Meet the speakers, SFRR-E ECR Webinar: Computational Redox Biology!

🗓 Tue 13 Jan 2026 | 🕒 15:00 CET | 📲 Zoom

Discover cutting-edge computational insights into redox biology with Cameron Schmidt & Karen Guerrero Vazquez.

us06web.zoom.us/j/8646973154...
Passcode: 433382

🌍New Funding Alert!
Apply for the CMM International Fund: up to £30k over 2 years for globally collaborative medical mycology research. FAPESP-funded PhD & Postdoctoral opportunities available for partnerships with researchers in São Paulo State, Brazil
🔗 www.exeter.ac.uk/research/med...

(BBSRC NWD CASE) Unravelling the origins, mechanisms and implications of species differences in cellular stress response pathway capacities at University of Liverpool on FindAPhD.com PhD Project - (BBSRC NWD CASE) Unravelling the origins, mechanisms and implications of species differences in cellular stress response pathway capacities at University of Liverpool, listed on FindAPhD...

📢 Fully funded PhD opportunity in my group!

Project title: Unravelling the origins, mechanisms and implications of species differences in cellular stress response pathway capacities.

Application deadline: 7 December 2025.

Details/apply: tinyurl.com/2jcp9jfz

Questions: Get in touch!

🌍🌎🌏Open to students worldwide! I m super excited for this project 🎉

Congratulations Colin!!! ❤️🎉 Can’t wait to see the super cool data will you generate!

Global analysis of translocon remodeling during protein synthesis at the ER - Nature Structural & Molecular Biology The authors use selective ribosome profiling to define how and when factors for N-glycosylation and membrane insertion engage and disengage from the core Sec61 translocation channel during biogenesis ...

This was a fun new collaboration using selective ribosome profiling to understand how the subunit composition of the ER translocon is tailored by the nascent chain. Congratulations to everyone involved!

www.nature.com/articles/s41...

How to apply for an EMBO Postdoctoral Fellowship: Tips from the Committee YouTube video by EMBO - excellence in life sciences

Want to apply for an EMBO Postdoctoral #Fellowship? 🧪

Here are tips from the EMBO Fellowship Committee:
www.youtube.com/watch?v=xY7c...
#LifeSciences #grant #funding

Translation landscape of stress granules Cryo–electron tomography visualizes stress granules in situ, revealing their spatial interplay with translation machinery.

What's the role of stress granules in translation? Here we provide a clue: we characterized the distribution of ribosomal complexes within SGs and reproduced this landscape with a phase-field model, pointing to a new regulatory mechanism. #TEAMTOMO www.science.org/doi/10.1126/...

🚀 Our new paper is out @natmethods.nature.com!

Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.

🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/

Mapping the genetic landscape of iron metabolism uncovers the SETD2 methyltransferase as a modulator of iron flux Genetic screens using endogenous reporters map key modulators of cellular iron, including the transcriptional regulator SETD2.

Happy to share latest work from the lab. Led by talented first author @awmartinelli.bsky.social. Mapping the genetic landscape of iron metabolism uncovers the SETD2 methyltransferase as a modulator of iron flux | Science Advances www.science.org/doi/10.1126/... Congratulations to all the team.

Rapid remodeling of NTP levels enables immediate translational adaptation to energy stress in yeast Bexley et al. report that rapid metabolic shifts mediate immediate, protective changes in RNA metabolism following energy depletion. In yeast, protein production is regulated by tuning enzymatic const...

www.cell.com/molecular-ce...

#RNAsky
💜💜💜💜💜💜💜

It was a super cool talk 🎉

On my way back from a truly brilliant yeast meeting! With more than 500 participants, so much cool science and loads of fruitful discussions, this week was remarkable! #yeast2025

I am in Paris this week for #yeast2025!

Lipoyl deglutarylation by ABHD11 regulates mitochondrial and T cell metabolism Nature Chemical Biology - Glutarate rewires cell metabolism through conjugation to proteins or fatty acids, but how glutarylation is regulated is unclear. ABHD11 was identified as a...

Delighted to share our latest work on ABHD11 as a novel deglutarylating enzyme, and its role in T cell metabolism @natchembio.nature.com rdcu.be/ewiYZ. Many congratulations to co-first authors Guine Grice, Eleanor Minogue and @hudsonwilco.bsky.social! Great team effort with Randall Johnson's lab.

Congratulations! 🎉

ROS transfer at peroxisome-mitochondria contact regulates mitochondrial redox Maintenance of mitochondrial redox homeostasis is of fundamental importance to cellular health. Mitochondria harbor a host of intrinsic antioxidant defenses, but the contribution of extrinsic, nonmito...

www.science.org/doi/10.1126/...

Our new preprint: how photoprotection is spatially coordinated with energy metabolism. Photosystem I is major source of radicals. We report EM structure of PSI in complex with superoxide dismutase SOD: direct link between energy conversion & oxidative stress defence
www.biorxiv.org/content/10.1...

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature Communications Redox signalling is emerging as an important regulator of metabolism and physiology, which is dysregulated in ageing and disease. Here, the authors show that redox regulation of a key redox sensitive ...

🎉Excited to share our latest paper, published in Nature Communications!🎉

"Enhancing autophagy by redox regulation extends lifespan in Drosophila"

#redox #metabolism #ageing #Drosophila

@natcomms.nature.com @mrc-lms.bsky.social

doi.org/10.1038/s414...

High-performance genetically-encoded green and red fluorescent biosensors for pyruvate Pyruvate is the end-product of glycolysis and a central metabolite involved in many biochemical pathways. However, a lack of high-performance (i.e., Δ F / F > 10) single fluorescent protein (FP)-base...

New tools! GreenPy and ApplePy are fluorescent biosensors for pyruvate with huge responses (20–40x in vitro) and a range of affinities (10s of μM to mM). These should be game changers for imaging of metabolism! Great work by Shosei Imai @sikmys.bsky.social and team 👏. www.biorxiv.org/content/10.1...

Localization of WDS proteins and fimbrin in three fungal species.

How do cells switch on the actin assembly at endocytic sites? How can this on-switch evolve? Check out our new preprint!
www.biorxiv.org/content/10.1...

1/27 We have a new paper out! Turns out that snowflake yeast have been hiding a secret from us - they've evolved a (very!) crude circulatory system. Not with blood vessels or a heart, but through spontaneous fluid flows powered by their metabolism. 🧪🔬

www.science.org/doi/full/10....

Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!

Congratulations to Dr Aphrodite Vasilaki and Dr Paraskevi Kritsiligkou @parikki.bsky.social who won the Leopold Flohé Redox Pioneer Young Investigator Award and Catherine Pasquier Award respectively at the 2025 Society for Free Radical Research International meeting
▶️ bit.ly/4ebZ9XN

Spent the day listening to some amazing talks from first and second year PhD students in our Biochemistry, Cell and Systems Biology Department! I loved how confident and knowledgeable our students are! Can’t wait for my students to give their talks next year 🥹

Thanks Ian! Glad you made it to the talk 🙂