Science, at its best, is a community effort.

From lifetime achievement to emerging talent, from research to outreach, there's an award for the neuroscientists who make our field great.

Submit your nomination for a 2026 SfN Award or Prize by Thursday, May 7.

🔗 vist.ly/4z5kf

#neurosky

Excited to share our latest in @currentbiology.bsky.social (they who publish the coolest papers!)

Memories are encoded by sparse neuronal ensembles (engrams). But most evidence comes from "simple" associative learning tasks. What about more integrative memories like spatial navigation?

some data on the shrinkage

Are these overlooked brain cells the key to treating trauma and anxiety? A growing body of research suggests astrocytes, star-shaped brain cells once dismissed as support players, may lead the way to more precise and effective psychiatric drugs.

www.nationalgeographic.com/health/artic...

Straight from the horse's mouth:

If Trump's proposed $5B cut to NIH were enacted in FY27, the number of new NIH research grants would drop **47%**

To be clear, this is from a document justifying the request. It's what they *want*. They think this is good.

officeofbudget.od.nih.gov/pdfs/FY27/br...

Astrocyte-Neuron Interactions in Neural Circuit Function and Dementia at Cardiff University on FindAPhD.com PhD Project - Astrocyte-Neuron Interactions in Neural Circuit Function and Dementia at Cardiff University, listed on FindAPhD.com

Wish I could do this PhD with Bal Khahk 😍

Newly appointed Fellow of the Royal Society, he is one of the best scientists to work with right now and joining the @ukdri.ac.uk in @cardiffuni.bsky.social

#neuroskyence #opportunities #careers #PhD #glia #

www.findaphd.com/phds/project...

You need to make AI guidelines for your lab Here's why you should, and how to start

I wrote about why every lab should have AI use guidelines, and how to do it.

open.substack.com/pub/blekhman...

Sex-specific APOE4-dependent innate immunity regulates meningeal lymphatics, brain lipids, neuroinflammation, and cognition Delivanoglou et al. show that expression of APOE4, a risk factor for Alzheimer’s disease, leads to sexually dimorphic lymphatic and inflammatory responses in mice and humans alike. Suppressing APOE4-i...

Sex-specific APOE4-dependent innate immunity regulates meningeal lymphatics, brain lipids, neuroinflammation, and cognition: Neuron www.cell.com/neuron/fullt...

UAB is recruiting neuroscience faculty at two different levels - come join our vibrant neuroscience community!

White House stalls release of approved US science budgets The US Congress rejected sweeping cuts to science agencies. But the NIH, the NSF and NASA have had their spending slowed.

Congress rejected massive cuts to US science budgets for 2026, but much of the money still isn’t flowing to researchers.

The culprit? The White House Office of Management and Budget (OMB) is quietly slow-walking the release of funds. 🧵👇

CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly - Nature CRISPR–Cas9 screening identifies CLCC1 as a factor that increases neutral lipid flux to prevent hepatic steatosis and promotes nuclear pore complex assembly by promoting membrane bending and fusi...

Sooo happy to share our new paper in @nature.com “CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.” A terrific collaboration with @arrudalab.bsky.social, led by co–first authors Alyssa Mathiowetz and Emily Maymand.
www.nature.com/articles/s41...

What accounts for the progression from healthy aging to Alzheimer's disease over an extended period of time?
The critical role of the immune system, particularly T cells and microglia.
A new, excellent review
www.cell.com/immunity/abs...

Line graph of the number new and competitive renewal grants funded by NIH in fiscal year 2026 through February 20, compared to fiscal years 2020-2025. The fiscal year 2026 is well below the other curves.

New and Competitive Renewals

Only 803 grants have been made compared to ~2650 in fiscal years 2023 and 2024 through February 20.

All institutes and centers (include OD now) have made awards except NIAAA, NLM, NCCIH, and FIC.

3/4

Limit on multiyear funding of NIH grants is a sticking point in Senate budget talks A clause limiting the use of multiyear NIH grant funding has become a sticking point as the Senate appropriations panel finalizes the HHS spending bill

Pre-long weekend story:

Multiyear funding for NIH grants has become a sticking point in negotiating HHS’s appropriations package for 2026

www.statnews.com/2026/01/16/n...

Doing a PhD is - at heart - one long discussion with your mentor. The discussion changes over time - with unexpected turns and ups & downs - but through it all is a pair of people discussing a topic endlessly to make sense of it.
PhD students: choose someone you like to talk to!

Lesion-remote astrocytes govern microglia-mediated white matter repair - Nature After spinal cord injury, lesion-remote astrocytes acquire heterogeneous, spatially restricted reactivity states that shape neuroinflammation, neural repair and neurological recovery.

Lesion-remote astrocytes govern microglia-mediated white matter repair

www.nature.com/articles/s41...

Phosphorylated tau exhibits antimicrobial activity capable of neutralizing herpes simplex virus 1 infectivity in human neurons
www.nature.com/articles/s41... @natneuro.nature.com

Neuronal fatty acid oxidation fuels memory after intensive learning in Drosophila - Nature Metabolism Neurons are shown to use fatty acid β-oxidation as a fuel source for memory formation upon intensive learning in Drosophila, challenging the view that neurons are unable to use fatty acids for energy ...

Textbooks said neurons don’t burn fatty acids for energy🤔. Our study delivers the first in vivo demonstration that fatty acid oxidation in defined memory neurons fuels memory formation.

Closing chapter of my PhD 🥳, out today in Nature Metabolism💥 @natmetabolism.nature.com

Metabolic, epigenetic and transcriptomic alterations in postnatal 16p11.2 deficient murine astrocytes Autism Spectrum Disorders (ASD) are associated with metabolic dysregulation. While astrocytes are integral to cerebral metabolism, their molecular and functional changes in ASD are poorly known. Using...

New preprint from the lab! For those who love astrocytes 🤩. We welcome feedback! #preprint #openaccess #astrocytes #autism

Update: a Targetome commentary by Zhao, Agarwal & Bai discusses our Cell paper as part of a broader paradigm of glia–glia coordination—linking microglia–astrocyte signaling in synaptic pruning to cooperative glial mechanisms in processes such as myelination.

www.maxapress.com/article/doi/...

Another great preprint on neuronal APOE4 from the Huang lab!

FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis - Nature Cell Biology Lange et al. identify a lipid droplet quality control pathway in which FSP1 safeguards stored neutral lipids from lipid peroxidation, thereby preventing the induction of ferroptosis.

#NatMetabPicks | In @natcellbio.nature.com led by @olzmannlab.bsky.social ( @ucberkeleyofficial.bsky.social )

FSP1, localized to lipid droplets, protects stored lipids from oxidative damage and prevents ferroptosis.

www.nature.com/articles/s41...

The Energetic Collapse of the Alzheimer's Brain: Metabolic Inflexibility Across Cells and Networks Metabolic inflexibility in Alzheimer's disease. Schematic illustrating the biphasic trajectory of metabolic activity relative to canonical Alzheimer's disease (AD) biomarkers. In the presymptomatic p...

Our new review is out today!

𝗧𝗵𝗲 𝗘𝗻𝗲𝗿𝗴𝗲𝘁𝗶𝗰 𝗖𝗼𝗹𝗹𝗮𝗽𝘀𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗔𝗹𝘇𝗵𝗲𝗶𝗺𝗲𝗿’𝘀 𝗕𝗿𝗮𝗶𝗻: 𝗠𝗲𝘁𝗮𝗯𝗼𝗹𝗶𝗰 𝗜𝗻𝗳𝗹𝗲𝘅𝗶𝗯𝗶𝗹𝗶𝘁𝘆 𝗔𝗰𝗿𝗼𝘀𝘀 𝗖𝗲𝗹𝗹𝘀 𝗮𝗻𝗱 𝗡𝗲𝘁𝘄𝗼𝗿𝗸𝘀

We argue that Alzheimer’s disease is not just a problem of brain hypometabolism, but a disorder of metabolic inflexibility.

onlinelibrary.wiley.com/doi/10.1111/...

The Cummings Lab is hiring a postdoc to work in the areas of reward and addiction! Please see the ad below:

Molecular profiling of brain endothelial cell to astrocyte endfoot communication in mouse and human - Nature Communications Deciphering body-brain communication pathways is key to a deeper understanding of brain physiology and pathology. Here, the authors define the astrocyte endfoot proteome and show dynamic vascular-to-a...

#astrocytes #endothelium #cerebrovascular 😱🤩🤩

Check out the latest WCM Newsroom article!! tinyurl.com/mry78yh8

Congratulations to the first author Daniel Barnett, a student in the @weillcornell.bsky.social Neuroscience Graduate program, and big thanks to our superb collaborators @liganlab.bsky.social @wjnyc.bsky.social, Haopeng Xiao, and Ed Chouchani🙏🙌

Thrilled to publish our new study on #mitochondrial ROS coming from complex III, revealing this key site in #astrocytes 🎯as a crucial immunometabolic signal transducer🤯 and potential therapeutic target for #dementia #FTD 💊 rdcu.be/eOc0m 👈💪 Great commentary by H. Pan and F. Yin🤩! tinyurl.com/4hdytw4c