You know how bakers make croissants? This is like if croissants made bakers

Image of a calcium calibration curve, calcium concentration traces of individual cells and lifetime images of cells

📣 New preprint alert! Co-authored by @spalaciosm.bsky.social and @andreacaldarola.bsky.social :
Quantitative imaging of calcium dynamics with a green fluorescent biosensor and fluorescence lifetime imaging
www.biorxiv.org/content/10.6...

Our cells are experts at navigating inherently noisy and complicated environments.

EMBL researchers are using theoretical physics approaches to uncover fundamental principles behind how cells use complex information to self-organise.

www.embl.org/news/science...

Fun with protein isolation beads. #FluorescenceFriday

Flyer with announcement of the FEBS advanced course in Amsterdam

Join us in Amsterdam for a FEBS advanced course on "Functional Imaging of cellular dynamics" from 31st of May - 6th of June 2026
Info: microscopy2026.febsevents.org

Latest work from the lab by Aude Nommick et al., in which we propose a "size-scaling" model for microtubule force exertion that regulates centrosome centration vs decentration during embryo development!
@ijmonod.bsky.social

www.biorxiv.org/content/10.6...

@joachimgoedhart.bsky.social 👀

Rare microbial relict sheds light on an ancient eukaryotic supergroup - Nature The discovery of an unusual protist named Solarion arienae, which has a mitochondrial genome with some intriguing features, provides insight into the early radiation of eukaryotic groups.

Each such discovery is a game changer for our understanding of eukaryote evolution, and this paper is no exception. Meet Solarion, which displays yet again novel types of subcellular structures. Congrats to all authors on a fascinating story. #protistsonsky
www.nature.com/articles/s41...

Three years later, has the $800M edX deal lost its luster? 2U’s acquisition of online course provider edX was once seen as a major win—and potentially even larger disrupter—in the OPM industry. Things didn’t go as planned.

4 years later the new owners are in deep debt anyway: www.insidehighered.com/news/tech-in...

How genetically encoded sensors have lit up neuroscience Tools that track specific molecules in neurons have enabled researchers to probe previously unexplored aspects of neurobiology — although important caveats remain.

Tools that track specific molecules in neurons have enabled researchers to probe previously unexplored aspects of neurobiology

go.nature.com/4p2hyua

Intestinal villus cells extrude living, following a calcium pulse. Unlike from extruding apoptotic cells, Ca2+ messaging stops at the first neighbors! #FluorescenceFriday

Part of our TrepatLab preprint: www.biorxiv.org/content/10.1...

Video by @ronjahoutekamer.bsky.social @gloerichlab.bsky.social

7 basic science discoveries that changed the world Ozempic, MRI machines and flat screen televisions all emerged out of fundamental research decades earlier — the very types of study being slashed by the US government.

Ozempic, MRI machines and flat screen televisions all emerged out of fundamental research decades earlier — the very types of study being slashed by the US government

go.nature.com/47hn0n5

🧠🌟🐭 Excited to share some of my postdoc work on the evolution of dexterity!

We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have:
(1) more corticospinal neurons (CSNs)
(2) better hand dexterity
(3) more dexterous climbing, which is linked to CSN number🧵

A study that monitored the expression and function of designer receptors called DREADDs in macaque monkeys for a period of three years demonstrates that they are effective in long-term studies of nonhuman primates.
buff.ly/WHU3w3s

These ancient bumblebees were found with their pollen source Insects have long pollinated plants, but evidence of ancient pairing is rare. Fossils now show bees and linden trees goes back 24 million years.

Scientists just found several fossil bumblebees covered in pollen that directly matches fossil flowers nearby.

The 24-million-year-old discovery reveals the oldest known evidence connecting pollinators to the pollinated.

#Paleontology #NationalFossilDay

🧪🏺

New at @sciencenews.bsky.social

Can't wait to try this out!

I’m happy to share some plugins I’ve been developping this summer: "Channels and Contrast" and LUTs Manager!
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...

Jane Goodall’s legacy: three ways she changed science The primatologist challenged what it meant to be a scientist.

Jane Goodall, known for her pioneering work with chimpanzees, has passed away aged 91

go.nature.com/46K10ja

I find that so many biologists are also talented artists.

@hsuanpai.bsky.social is a skilled technician and apparently good at any artistic media she touches.. even LB.

My initial assessment of this paper ⬇️ was brief, so let’s have a better look at it:
🧵

Another #FluorescenceFriday, another movie of the cytoskeleton.

This time around EB3-mScarlet3 and LifeAct-mStayGold co-expressed in U2Os cells!

LUTs here (Ink collection)--> sites.imagej.net/JDM_LUTs/luts/

Today is National Lighthouse Day honoring the historical and cultural significance of lighthouses. I've posted this image before but have reprocessed it. It is the lighthouse at St. Marks Florida. #photography #landscape #EastCoastKin #bnw #blackandwhitephotography #infrared #fullspectrum #clouds

🐙 This Octopus shifts from deep to active rest while "dreaming" for #MicroscopyMonday. REM‑like sleep (color bursts and twitches) filmed in real time by Horst Obenhaus @octoscience.bsky.social‬, currently a 2025 Whitman Fellow at @mblscience.bsky.social. #NESM

#Octopus #Neuro #SleepScience #MBL

One protein, two opposing roles: This ‘compelling’ study shows how the same signalling molecule can drive either protrusion or retraction in migrating cells depending on its concentration and activation dynamics.
buff.ly/pMGXJVM

Plasmid here 🧬➡️ www.addgene.org/Dorus_Gadella/

A very late #FluorescenceFriday.

Reposting one of my favorite timelapses from the past year: EB3-mScarlet3 in a HeLa cell, look at those microtubules grow!

Phage therapy: I found a bacteria-eating virus in my loo It's hoped phages could give us new ways of treating infections which are immune to antibiotics.

News article on the project:

ThePhageCollectionProject

Shout-out to The Phage Collection Project run by @fnobrega.bsky.social

You can order your very own samplng kit and help with the discovery of new phages to combat antibiotic resistance!

Check their website for more info ➡️ www.phage-collection.org

Proud to work with and learn from an extraordinary biologist 🔬