Exploring the Structural Lexicon of the Proteome via Metric Geometry The three-dimensional structure of proteins is intimately linked to their function, yet establishing comprehensive frameworks for systematically comparing and organizing protein structures across the ...

New preprint from our lab: We investigate how Gromov-Wasserstein couplings can be applied to protein structure alignment and analysis, with fascinating results. Fantatisc work by Elijah Gunther! www.biorxiv.org/content/10.1... #ProteinStructure #MetricGeometry

The goal of a PhD is not to learn some facts or read a few papers or learn a bunch of techniques. The goal of a PhD is to learn independence, problem solving, how to finish things you start, resilience, & gain the ability to adapt & think creatively. Learning these things is hard.

Multiple autism genes influence GABA neuron remodeling via distinct developmental trajectories Abstract. Variation in over 100 genes are now associated with increased risk for autism and related neurodevelopmental conditions, but how this variation r

Do you like neuronal #plasticity? #genetics? #Celegans? Check out 1st installment of work by Kristi Zoga in the lab. Kristi screened 20 conserved #autism genes for roles in experience-dependent #neuron remodeling and a related behavior.
doi.org/10.1093/genetics/iyaf156