Lovely highlight of a new fascinating study by @ehoffmanlab.bsky.social 🐟💊

For those interested, 🔗 to original research: www.pnas.org/doi/10.1073/...

Molecular and functional dissection using CaMPARI-seq reveals the neuronal organization for dissociating optic flow-dependent behaviors Nature Communications - In this study, the authors develop CaMPARI-seq to link neural activity with molecular profiles in larval zebrafish. They identify inhibitory pretectal neurons required for...

Happy to share our new paper published in Nature Communications!
www.nature.com/articles/s41...
We developed CaMPARI-seq to link neural activity with molecular profiles and revealed how the brain distinguishes optic flow to guide behavior. Congratulations to our postdoc Koji Matsuda!

Congrats on the beautiful story, Fumi! 🥳

Immune modulation promotes heart regeneration through macrophage and Granulin functions in medaka | PNAS Myocardial infarction results in irreversible cardiomyocyte loss and fibrotic remodeling in adult mammals, whereas some vertebrates retain the abil...

🚨 Turning on heart regeneration through immune modulation?
Led by @kcinc.bsky.social, we show that activating pro-regenerative macrophages induces Granulin, a key driver of cardiomyocyte proliferation and scar resolution in medaka, now published in @pnas.org 💔➡️❤️
www.pnas.org/doi/10.1073/...

New work from @ehoffmanlab.bsky.social 🐟

🔗 to original research: www.pnas.org/doi/10.1073/...

A scaled collection of brains from common neuroscience model organisms arranged side by side. From left to right: a large human brain and a smaller macaque brain on the top row; below them progressively smaller brains from a marmoset, rat, mouse, zebrafish, and a tiny Drosophila (fruit fly). A coin provides size reference. An inset shows a small, irregularly shaped brain organoid.

I created this collection of common brain models in neuroscience, all to scale

Across species, brains share fundamental principles and many homologous regions

But as size increases, complexity and connectivity change. We need the full spectrum, from flies to rodents, non-human primates, and humans

IL-22 from enteroendocrine cells promotes early-life gut motility in zebrafish through the microbiota The gut microbiota, immune system, and enteric nervous system interact to regulate adult gut physiology. However, the mechanisms establishing gut physiology during development remain unknown. We repor...

Very happy to share this study from our group and colleagues now out in Science!
We found that in zebrafish, before the immune system is mature, gut epithelial cells perform immune functions by producing the cytokine IL-22 to shape the microbiota to promote early life gut function
#Zebrafish #Gut

A transcriptomic microglia taxonomy across mouse and human pathologies www.nature.com/articles/s41...

Congrats! 🥳🥳

Thanks for sharing such a beautiful story of Ben! ❤️

I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.

“Here we present ZMAP (Zebrafish Meta Atlas Project), a harmonized reference integrating 8 published whole-embryo zebrafish scRNA-seq datasets comprising 798,790 cells across 15 developmental time windows.” 🐟 🧪

New work from @danwagnerlab.bsky.social

🔗 to WebApp: wagnerlabucsf.github.io/zmap/

Congrats! 🥳

Department of Biology Join me and make a gift to Gator Giving Day 2026

It's #GatorGivingDay and we're almost at our goal! Every $$ supports our wonderful students and community here at @sfstatebio.bsky.social Thank you for your support!

giving.sfsu.edu/schools/SanF...

Undergraduate student Alexandra Jose shares “SFSU has provided me with such amazing opportunities to let me pursue my academic goals, contribute to research that inspires me, and be part of an incredible community!” Your gift makes such research opportunities possible. #GatorsGiveDay

“Here, we combined inducible lineage tracing, single-cell RNA sequencing and morphological analysis to define the molecular and structural features of Muller glia derived neurons in the adult zebrafish retina [following injury]”

New work from Thanh Hoang et al. at University of Michigan 🐟 👁️

Pupae and pupal gut in wt and Mmp2-knockdown

New paper from @uwe689.bsky.social !

Muscle and #ECM remodeling during fly metamorphosis is still poorly understood. Why? Pupae are really hard to work with.

Uwe took on the challenge and explored how Mmp2 contributes to this amazing morphogenetic process.

www.nature.com/articles/s41...

#cellbio

Youthful antics predict lifespan? Using machine learning & continuous recordings of #killifish behavior from adolescence until death, @brunetlab.bsky.social & @deisseroth.bsky.social find early-life behavior predicted future lifespan! Now published @science.org: www.science.org/doi/10.1126/... 🧪 1/2

Thanks Wendy! Things are coming along 😃

Xin Lab Welcome! We study the cellular interactions between neurons and oligodendrocytes, which produce myelin in the central nervous system. Myelination - the process by which oligodendrocytes ensheath neuro...

Super stoked to share that I’m starting my lab at UHN @dkjei-uhn.bsky.social / @kbi-uhn.bsky.social and the University of Toronto!

If you’re interested in neuron-myelin interactions in circuit maturation and cognition, please reach out - we are hiring!

www.oligodendrocyte.org

1/

Amazing, congrats! 🥳

Brain-engrafted monocyte-derived macrophages from blood and skull-bone marrow exhibit distinct properties. @cp-neuron.bsky.social www.cell.com/neuron/fullt...

Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition Immune cells populate the old brain, but whether they can be specifically targeted to improve brain function in older individuals remains unclear. Navarro Negredo et al. dissect how aging impacts brai...

Excited to share our new study using engineered immune proteins to quench inflammation in aged brains!!

Congratulations to Paloma Navarro and the entire team!

Fantastic collaboration with Chris Garcia's lab, Tony Wyss-Coray's lab, and Saul Villeda's lab!

www.cell.com/immunity/ful...

Fintastic meeting as always, for those interested! #ZebrafishMeeting

🐟👀 SFSU Biology seminar — Thu Mar 5
2–3pm | SEC 116
Dr. Patricia Schneider (LSU): “Split Screens: Exploring Vision through the Eyes of the Four-Eyed Fish.”
Student time: 3–3:30pm. Come by!

Endogenous retrovirus-derived RNA-DNA hybrids induce microglial synaptic pruning in autism models @cp-neuron.bsky.social www.cell.com/neuron/fullt...

🧠 SFSU Biology Special Seminar
Dr. Biswa Ramani, MD, PhD (UCSF) — neurodegeneration + neuropathology + physician-scientist career path
📅 Wed 2/25/2026 • 🕙 10:00–11:40 • 📍 Hensill Hall 233 Hosted by @nicholasjsilva.bsky.social
All welcome!

Axolotls wow scientists by regenerating this complex organ Axolotls can completely rebuild their thymus, a key immune organ

Axolotls can completely rebuild their thymus, a key immune organ

Myelin sheaths in the central nervous system can withstand damage and dynamically remodel Myelin damage is a hallmark of several neurological disorders, but how it occurs remains to be fully understood. In this study, we found that early damage in zebrafish and rodent demyelination models ...

Latest from the lab, led by @ara-donia.bsky.social and @juliavdkorput.bsky.social

Huge team effort, with immense contributions by friends from nearby and around the globe.

www.science.org/doi/10.1126/...

Congrats on the amazing story! 🥳