Sweet! The cell’s sugary coating comes into view Built from thickets of glucose, galactose, mannose and more, the glycome plays key roles in cell communication, immunity and the blood-brain barrier

“glycans direct communication and the exchange of materials between cells…guide immune responses and substantially affect a cell’s functions and growth; they’re exploited by disease-causing viruses and other pathogens to gain entry”
#Glycans #CellBio #Science
knowablemagazine.org/content/arti...

Awesome picture Mathieu! 🔥

These fingerprint-actin ridges look so cool... is it known how they form?

#cellbio #development #devbio #cytoskeleton #zebrafish #danio

Interested in uncovering how the #Golgi reacts to stress? Apply NOW to the @hellerschmiedlab.bsky.social @imprs-lm.bsky.social #chembio #cellbio #biochemistry

Wait a moment...

...bee lice are THAT closely related to Drosophila?

I had no idea... why isn't there much more evodevo and morphogensis work on bee lice? This divergence from the "normal" Drosophilid bauplan is just... crazy

#EvoDevo #CellBio #Morphogenesis #Development #Devbio

Pupae and pupal gut in wt and Mmp2-knockdown

New paper from @uwe689.bsky.social !

Muscle and #ECM remodeling during fly metamorphosis is still poorly understood. Why? Pupae are really hard to work with.

Uwe took on the challenge and explored how Mmp2 contributes to this amazing morphogenetic process.

www.nature.com/articles/s41...

#cellbio

This was such a fantastic meeting!

I’m back home now… with my head (and my notebook) full of new ideas 😊

Thanks to the organizers at @gfeev.bsky.social , @sebioldev.bsky.social and DSDB!

#devbio #cellbio #gfe26

(A) 3D reconstruction of a mitotic cells from prophase to cytokinesis, highlighting the cell membrane (grey), nucleus (blue) and chromosomes (purple). (B) Metaphase cell superimposed on a z-stack slice showing chromosomal volumetric progression; descending shades of purple denote size (large, >3 μm3; medium, 2–3 μm3; small: <2 μm3), with sex-linked chromosomes in dark pink.

Nickhil Jadav, Sailakshmi Velamoor, Duane Harland, Mihnea Bostina and colleagues use volume electron microscopy to uncover mitotic ultrastructure in the native hair follicle.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
#cellbio #volumeEM #vEM

Finally I can join #FluorescenceFriday as a theorist 😊.

This is a DNA-PAINT recording of E-Cadherin and F-actin in Drosophila embryonic epidermis. You can see E-cadherin clusters and their counterparts across junctions. Cover in @biophysj.bsky.social . doi.org/10.1016/j.bp... #devbio #cellbio

The wonderful historic city of Marburg

🚨 University Marburg (Germany) is recruiting a W2 Professor of Mol. Pharmacology in the Faculty of Medicine.

Focus areas: Epithelial adaptation in #inflammation, #regeneration, and/or #cancer

stellenangebote.uni-marburg.de/jobposting/0...

#AcademicJobs #Pharmacology #FacultyPosition #cellbio

Painting of a large round purple nucleus surrounded by ER in green. The nuclear membrane has ruptured, revealing a tangle of broken chromatin strands. A bright orange light shines out of the rupture. Pink cytoplasm is stretched behind the nucleus.

WIP of the painting described previously. Nucleus, ER & light blocked in.

First draft of painting described previously. Sketch of ER visible with nucleus & chromatin blocked in.

Latest painting… think I’ll call it “Pop goes the nucleus” 🧪

Still feel the need to add details but ready to share where it stands for now 🥲🎨

acrylic on canvas board

#sciart #painting #art #postdoc #cellbio

Postdoc Research Group Schur The Schur lab at the Institute of Science and Technology Austria (ISTA) has an open postdoc position for a highly motivated candidate to be part of our ERC-funded project ActinID. Our Group ...

Open Postdoc position in our lab!
#actin #Huntingtin #cryoET #cellbio
If you enjoy working at the interface of cell biology, structural biology, and quantitative imaging, this could be an excellent fit.

ista.ac.at/en/job/postd...

Please share and feel free to reach out if there are questions!

Only a few spots left for this amazing meeting! Just sign up and join us to discuss all #cellbio #imaging things!

Aging researchers find new puzzle piece in the game of longevity The lab of Kris Burkewitz just made a key discovery: How cellular machineries are structured and organized within a cell has implications for healthy aging. “We didn't just add a piece to the puzzle—w...

The original post from Vanderbilt
#CellSky #Aging #CellBio 🧪
medschool.vanderbilt.edu/basic-scienc...

Ever wanted to hold a cilium in your hand? 🧬✨

Here is a look at how I’m using CiliaBuilder in @UCSFChimeraX to generate accurate 3D prints of centrioles and cilia. Perfect for teaching or lab displays!

Watch the process: youtu.be/IKnnp3ovptQ #CryoEM #CellBio #ChimeraX

Ca2+ and DRP1 drive endocytic lysosome reformation at tripartite contact sites Lysosomes are essential in maintaining cellular health. Endocytic lysosome reformation (ELR) regenerates functional lysosomes following degradation of endocytic cargo, yet the mechanisms driving this process remain largely unknown. Here, we define the molecular machinery underlying ELR. We find that unlike autophagic lysosome reformation (ALR), ELR proceeds independently of mTOR and dynamin 2, but requires the mitochondrial fission GTPase DRP1. DRP1 mediates scission of endolysosomal tubules at contact sites with the endoplasmic reticulum (ER) and mitochondria. Disruption of DRP1 function or ER endolysosome contact results in elongated tubules, indicating defective lysosome reformation. Moreover, mitochondrial activity is essential for tubule initiation, and Ca2+ transfer from endolysosomes to mitochondria is crucial for ELR onset. Our findings reveal a dual role for mitochondria in ELR: first in ELR initiation and second in DRP1-dependent tubule fission at ER-mitochondria-endolysosome tripartite contact sites, uncovering the previously unappreciated role of mitochondria in endolysosome remodeling and fission. ### Competing Interest Statement The authors have declared no competing interest. Swiss National Science Foundation, 320030-231859, 310030-197779 University of Basel, https://ror.org/02s6k3f65

Check out our newest findings on how #lysosomes are generated from #endolysosomes. Great work from @samit2104.bsky.social ! @biozentrum.unibas.ch , @unibas.ch #cellbio #cell #organelles
Ca2+ and DRP1 drive endocytic lysosome reformation at tripartite contact sites www.biorxiv.org/content/10.6...

Active flows drive clustering and sorting of membrane components with differential affinity to dynamic actin cytoskeleton - preLights The cell cortex behaves like a sorting hat: it groups membrane proteins by how tightly they bind to dynamic actin.

The cell cortex behaves like a sorting hat: it groups membrane proteins by how tightly they bind to dynamic actin. 🪄🎩

Insightful post from Teodora Piskova covering recent work of the #MayorLab & team @ncbsbangalore.bsky.social #CellBio #preprint

#preLight ⬇️
prelights.biologists.com/highlights/a...

A calico cat eager before a cell bio lecture

A calico cat fell asleep during cell bio lecture

20” of snow & counting in CNY!

Belle was not impressed today’s #cellbio lecture on zoom. Slept through her kibble dispenser & her cameo on X-chromosome inactivation in calico cats. #newPI

Microscopy preprints – applications in biology - FocalPlane Microscopy preprints – applications in biology - News

Our #preprint list is now up on FocalPlane. This week we are highlighting the latest research using microscopy to answer questions in biology, including preprints on #cellbio, #devbio, #neurobio, #virology and #microbio. Let us know if you have any recommendations for preprints to add to our list.

Making one final call in search of a few more #insect, #fish, & #fungi options for my #cellbio course's final proj on 'emerging' model organisms. 🐝🐜🐛🐟🐠🦈🐬🍄

#cellbiology #biology #entomology #icthylogy #mycology 🧪 (1/2)

images of a coccolithophore using light microscopy

Today marks my new fav #newPI fail... I unknowingly 6-7'd my #cellbio class (my TA asked if it was intentional after lecture)🤦‍♀️

I used #coccolithophore examples for #microscopy talk... Was literally talking about the upper limit of Ghux diameter. Don't think my lab will let me live this one down.

Lab group at breakfast table

A professor teaching cell biology

Happy spring 2026 semester from the Reich Lab! 🧪

We celebrated with a lab breakfast but the flow cytometer threw a hissy fit. Also back to lecturing #CellBio to 90(!) my largest group yet.

we will see what tomorrow brings #newPI

It's that time of year again! I'm looking for suggestions of 'emerging' model organisms for my #CellBio course's final proj:

Organism nomination form here (links to blog on proj info): forms.office.com/r/v8zYgqVe8W

#cellbiology #biology #academicsky #microsky #archaeasky #protistsonsky 🧪 (1/n)

👁️I spy our Scientific Advisory Board members on the @jcellsci.bsky.social cover.
FocalPlane is a youngster at 5 years old, but we're looking forward to continuing our development in 2026 with the help of the #microscopy and #cellbio communities.

Join us to study developmental cell biology with a focus on cell migration and morphogenesis.

More info about our research:
www.bischofflab.com

Job posting and application details:
focalplane.biologists.com/cell-biology...

#Science #CellBio #DevBio #AcademicJobs #PhDJobs #PhDPosition #Drosophila

Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer Changes in pancreatic cancer cell shape are correlated with treatment response and are associated with cellular functions.

Nanolive is proud to see our technology forming part of a new methodology for the phenotypic profiling of different cell lines and treatment conditions alongside fluorescent cell painting, and #transcriptomics.

www.science.org/doi/full/10....

#DrugScreening #Innovation #CellBio

𝗛𝗮𝗽𝗽𝘆 𝗡𝗲𝘄 𝗬𝗲𝗮𝗿 𝗳𝗿𝗼𝗺 𝗡𝗮𝗻𝗼𝗹𝗶𝘃𝗲 🎉
For the year ahead, may your cells defrost well, may your cultures stay mycoplasma-free, and may all your imaging acquisitions yield high-impact results! Here’s to a great 2026!
#2026 #HappyNewYear #CellBio

Switching Gears: Metabolic Rewiring in Cancer #MetabolismMondays - the Node This week, we explore the story of Dr. Luis Cedeno-Rosario, a postdoctoral researcher in the Rutter Lab at the University of Utah.

@luisci22.bsky.social, postdoc @uofubiochem.bsky.social , decoding how cancer cells rewire their metabolism to alter their cell fate !
#cancerresearch #stemcellresearch #cellbio

#ICYMI
As the year is ending, once again sharing my #MetabolismMondays articles for @the-node.bsky.social during my first year as one of #theNodeCorrespondents !

#devbio #stemcell #metabolism #cancerresearch #immunology #evodevo #viruses #evolution #adaptation #regeneration #cellbio #biochem

Want to do great science and beautiful microscopy with a great guy? @maikbischoff.bsky.social is recruiting a PhD student for his new lab!

#cellbio #devbio #microscopy #bioimaging