Multiple origins and functions: evolutionary pathways of HSP70 proteins in viruses Heat shock protein 70s (HSP70s) are highly conserved molecular chaperones found across all domains of life, where they play essential roles in cellular stress responses. Whilst HSP70 homologues have been previously identified in closteroviruses that have ssRNA genomes, their broader presence and evolutionary history in viruses remain poorly understood. In this study, we conducted a comprehensive search of viral protein databases and identified HSP70 homologues in viruses beyond those with ssRNA genomes, including examples with dsDNA genomes in the class Megaviricete. These viral HSP70s exhibit diverse gene organizations, copy numbers and structural features. Notably, HSP70s of viruses from Megaviricetes showed up to three gene copies per genome and distinct structural motifs, whilst those from closteroviruses displayed higher sequence and structural diversity, suggesting faster evolutionary rates. Structural and phylogenetic analyses revealed two major clusters of viral HSP70s, with dsDNA virus HSP70s closely resembling those of their protist hosts, supporting the hypothesis of horizontal gene transfer. In contrast, ssRNA virus HSP70s formed a distinct, highly divergent group. Our findings suggest multiple independent acquisitions of HSP70 genes by viruses and provide new insights into their evolutionary trajectories and potential functional adaptations.

Virus HSP70s show multiple independent origins, with distinct evolutionary paths in ssRNA and dsDNA viruses, highlighting #HorizontalGeneTransfer and functional diversification.🧬🔥#Virology #Evolution #HSP70 #MolecularEvolution
📄https://doi.org/10.1099/jgv.0.002242
👤EVBC: Santiago F. Elena

Rage against the mean: a perspective on measuring fitness of individual phage particles - npj Viruses npj Viruses - Rage against the mean: a perspective on measuring fitness of individual phage particles

@paulturnerlab.bsky.social and I wrote a perspective on the need and recently developed approaches to study individual virus traits in the most numerous viruses on our planet (phages).

Let's move beyond measuring the mean #phagesky

www.nature.com/articles/s44...

#microsky #virology #microscopy

What covers the genetic material in a virus? Cell wall Envelope Protein coat Cytoplasm #genetics #vi What covers the genetic material in a virus? Cell wall Envelope Protein coat Cytoplasm #genetics #vi

What covers the genetic material in a virus?
Cell wall
Envelope
Protein coat
Cytoplasm
#genetics #virus #virology #biology ... Continue to: www.facebook.com/113009240922...

Advancing antiviral strategies through 🇪🇺 cooperation. 🧬

#AVITHRAPID #HorizonEurope #DrugDesign #Virology #ClinicalTrials #Dengue

Exposing tumors: Why some cancers are especially hard to treat Some tumors go into

New on the LJI Blog —

Some tumors go into "stealth mode." Here's how scientists are fighting back: bit.ly/4v7lC0d

#Cancer #CancerImmunotherapy #Virology #Health #Medicine

Diagram showing the current infection rates for influenza viruses in Germany over different seasons. Incidence rates for the age groups 0-14 years: 1.86, 15-59 years: 0.58, 60 and above: 1.91, with an overall incidence of 1.16. In week 13, there were 968 infections, compared to 9,416 in the previous season.

This week's influenza infections for Germany. 🦠
This week, 968 infections per 100,000 citezens were detected.

Created on 2026-04-02.🗓️
CREDIT: Data was obtained from the Robert Koch-Institute under CC BY 4.0 licence. #Influenza #Virology #Epidemiology #PublicHealth #Flu #EpiSky #IdSky #FluSky

I’m pleased to share my recent peer-review activity with Elsevier for Q1 2026.

🔬 Review History Highlights:
• Contributions to:
– Preventive Veterinary Medicine
– The Veterinary Journal
– Virology

#PeerReview #ScientificResearch #VeterinaryMedicine #Virology #Elsevier #AcademicService

#1232 Michael Mann - Science Under Siege: The Five Most Powerful Forces that Threaten Our World by The Dissenter ******Support the channel******Patreon: https://www.patreon.com/thedissenterPayPal: paypal.me/thedissenterPayPal Subscription 1 Dollar: https://tinyurl.com/yb3acuuyPayPal Subscription 3 Dollars: https...

Typically, it's a person's, or culture's, ideology that causes implicit & explicit #science denial

The Dissenter: #1232 Michael Mann - Science Under Siege: The Five Most Powerful Forces that Threaten Our World

Media file: anchor.fm/s/822ba20/po...

#ClimateChange #virology #politics #health

Original post on mastodon.social

Typically, it's a person's, or culture's, ideology that causes implicit & explicit #science denial

The Dissenter: #1232 Michael Mann - Science Under Siege: The Five Most Powerful Forces that Threaten Our World

Episode webpage […]

First European case of H9N2 bird flu reported in Italy – what you need to know | The-14 First European human case of H9N2 bird flu reported in Italy. Learn what scientists say about risks, transmission, and why the public should remain calm today.

First European case of H9N2 bird flu reported in Italy – what you need to know
#BirdFlu #H9N2 #PublicHealth #HealthNews #Influenza #Virology #GlobalHealth #DiseaseOutbreak #HealthAwareness #MedicalNews #ScienceNews #Epidemiology #Prevention #Healthcare
the-14.com/first-europe...

Mapping active herpesvirus replication inside human neurons 🧠🔬

A max intensity projection of HSV-1 infecting LUHMES cells.
🔵 Actin: The dense structural network.
🔴 HSV-1: Hotspots of active viral replication.

Infections are undesirable, but beautiful!

#sciart #virology

Lassa Virus Live Tracking and Lineage Assignment: How Nextstrain Can Enhance Surveillance and Public Health in Africa and Beyond Lassa virus (LASV), a zoonotic, bi-segmented arenavirus endemic to West Africa, causes seasonal epidemics with substantial morbidity and mortality. Increasing frequency of exported cases emphasises...

New article shows how #Nextstrain based live tracking and lineage assignment for #LassaVirus can strengthen #GenomicSurveillance and #PublicHealth response in Africa and beyond 🔬🦠🌍 #Virology
📄 https://doi.org/10.1080/22221751.2026.2640699
👤 EVBC: Knut Reinert, Denise Kühnert

A #cytomegalovirus-encoded lncRNA blocks cell-cycle progression.

HCMV lncRNA RNA2.7 stabilizes host mRNAs & enforces G1–S arrest, boosting viral replication through mRNA control & cell‑cycle blockade.

www.sciencedirect.com/science/arti... #virology #MicroSky

End of the line...
#virology #genomics

Congratulations to Dr. Shirin Geravandi on receiving the Poster Award, sponsored by the Journal of Virology for her work on immune reponses of HIV-1-exposed uninfected children at last week’s 2026 Annual Meeting. #GfV2026 #Virology #GlobalHealth #Immunology #HIVResearch

Prenatal Zika virus exposure disrupts social-emotional development and cortical visual function in infant macaques - Nature Communications Prenatal Zika virus (ZIKV) exposure can lead to a spectrum of developmental issues, but the mechanisms remain unclear. Here the authors show that prenatal ZIKV exposure in macaques disrupts neurodevelopment, causing prolonged maternal attachment and visual deficits at 3 months that normalize by 12 months, independent of sensory function.

#Virology

Prenatal exposure to #Zika virus disrupts social-emotional development and cortical visual function in infant macaques

@mohrlab.bsky.social

Skin's immune response could be key to fighting dengue Dengue, a mosquito-borne viral disease, infects an estimated 390 million people and causes around 20,000 deaths worldwide each year. New research suggests the skin is a major site of immune…

#Skin's immune response could be key to fighting #dengue ...

| #virus | #pathogen | #virology | #infections | #ImmuneResponse | By @bristoluni.bsky.social via @sciencex.bsky.social

Diagram showing the current infection rates for influenza viruses in Germany over different seasons. Incidence rates for the age groups 0-14 years: 3.39, 15-59 years: 1.03, 60 and above: 3.78, with an overall incidence of 2.18. In week 12, there were 1,827 infections, compared to 12,851 in the previous season.

This week's influenza infections for Germany. 🦠
This week, 1,827 infections per 100,000 citezens were detected.

Created on 2026-03-26.🗓️
CREDIT: Data was obtained from the Robert Koch-Institute under CC BY 4.0 licence. #Influenza #Virology #Epidemiology #PublicHealth #Flu #EpiSky #IdSky #FluSky

Coronavirus Infection | Disease Areas | MedChemExpress Coronavirus infection, encompassing diseases such as COVID-19 and long COVID, represents a significant global public health challenge driven by the novel coronavirus, requiring coordinated prevention ...

🧪MedChemExpress continues to support COVID-related research: medchemexpress.com/disease-area...
🔖Read more: pmc.ncbi.nlm.nih.gov/articles/PMC...

#BA32 #COVID19 #SARSCoV2 #Variants #Virology #Immunology #GlobalHealth #NewCOVIDVariant

Happy to share EVBC Newsletter No. 101 (March 2026) including:
📢 Info on ViBioM 2026
📜 Newest EVBC member publications
📅 Upcoming events
💼 Open vacancies
🎤 Webinar announcements
🔗 https://evbc.uni-jena.de/evbc-newsletter/
#bioinformatics #virology

New Covid variant has been identified and is already spreading in 25 states Researchers say the strain could evade protection from current Covid shots

New #COVID #variant has been identified and is already spreading in the United States ...

| #SARSCoV2 | #MicroSky | #virology | #coronavirus | #COVID19 | #pathogen | #infections | By @juliaelenamusto.bsky.social via @the-independent.com

www.independent.co.uk/news/health/...

HPV-positive cancers hide from the immune system, but blocking a single protein could make the tumors treatable A team of scientists at Henry Ford Health + Michigan State University Health Sciences have uncovered a mechanism that allows certain head and neck cancers to hide from the immune system, a discovery…

#HPV-positive #cancers hide from the immune system ...

| #HumanPapillomavirus | #ImmuneSystem | #tumors | #microbiology | #virology | By @michiganstateu.bsky.social via @sciencex.bsky.social

Court rejects AIDS Healthcare Foundation's bid for emergency injunction to stop cuts • Florida Phoenix A circuit court judge has ruled that the administration of Gov. Ron DeSantis can push ahead with reductions to a program that helps people with HIV and AIDS purchase life-saving drugs. Circuit Judge J...

Florida's cuts to Ryan White program can proceed. Some 32,000 people may lose access to HIV/AIDS medications.

#Medsky #healthlaw #healthpolicy #IDsky #publichealth #drugcosts #pharma #HIV #virology

Metagenomic approaches identify diverse tick-borne viruses in Hulunbuir, Inner Mongolia.
doi.org/10.15212/ZOO...
#TickBorneViruses #Metagenomics #Virology #PathogenDetection

#Virology and #PandemicPlanning

go.bsky.app/E3MmmPr

Prenatal Zika virus exposure disrupts social-emotional development and cortical visual function in infant macaques - Nature Communications Prenatal Zika virus (ZIKV) exposure can lead to a spectrum of developmental issues, but the mechanisms remain unclear. Here the authors show that prenatal ZIKV exposure in macaques disrupts neurodevelopment, causing prolonged maternal attachment and visual deficits at 3 months that normalize by 12 months, independent of sensory function.

#Virology

Prenatal exposure to #Zika virus disrupts social-emotional development and cortical visual function in infant macaques

@mohrlab.bsky.social

During the ICGEB @UKZN course on Translational Virology, ICGEB Director-General Lawrence Banks met former fellows from his lab: Carly Burmeister @UCT_news Esihle Monelo and Linda Ratjama @NUST_Namibia #ICGEBAlumni #CapacityBuilding #Virology #Africa

During the ICGEB #UKZN course on Translational Virology, ICGEB Director-General Lawrence Banks met former fellows from his lab: Carly Burmeister #UCT_news Esihle Monelo and Linda Ratjama #NUST_Namibia

#ICGEBAlumni #CapacityBuilding #Virology #Africa

A comprehensive analysis of the SARS-CoV-2 omicron variant in Tocantins State, Brazil, and tracing the spread of the XBB.1.18.1 lineage - Brazilian Journal of Microbiology Brazilian Journal of Microbiology - This study presents a genomic and epidemiological exploration of the omicron variant sublineages in Tocantins, Brazil. A total of 556 positive samples, obtained...

Read the full article:
doi.org/10.1007/s427...

#SARSCoV2 #COVID19 #GenomicSurveillance #Phylogenetics #OneHealth #Epidemiology #Omicron #XBB #PublicHealth #Brazil #Virology #Genomics #Labinftec 10/10

Quickly forwarded this to a friend who's grudgingly going on a cruise next week--on a ship that holds 6,000 people.

#IDsky #publichealth #virology #travel #infectiousdisease #norovirus

Controlled human #influenza infection reveals heterogeneous expulsion of infectious virus into air.

MIST captures & analyzes infectious influenza in expelled particles, revealing wide individual variability.

www.sciencedirect.com/science/arti... #virology #flu #MicroSky