Sweet! The cell’s sugary coating comes into view Built from thickets of glucose, galactose, mannose and more, the glycome plays key roles in cell communication, immunity and the blood-brain barrier

“glycans direct communication and the exchange of materials between cells…guide immune responses and substantially affect a cell’s functions and growth; they’re exploited by disease-causing viruses and other pathogens to gain entry”
#Glycans #CellBio #Science
knowablemagazine.org/content/arti...

Sweet! The cell’s sugary coating comes into view Built from thickets of glucose, galactose, mannose and more, the glycome plays key roles in cell communication, immunity and the blood-brain barrier

In HS biology we learn about DNA, RNA, proteins. My @knowablemag.bsky.social story describes the other major building block of life: #glycans
knowablemagazine.org/content/arti...

This is Huge! #healthcare #science #MIT #cancer #immunotherapy #glycans #lectins #ABLecs #FCancer #biotech #innovation #hope 🦋

#Glycans probably have more "copies/cell" than #proteins and changes in #glycosylation could potentially be remarkable biomarkers for diseases as well as targets for therapeutics. This post explores the abundance of glycans on the cell surface and it is worth a read to recognize these #biomolecules.

New week, new paper out: mirror-image #glycans are still rarely used to design #carbohydrate materials, but they can reveal the rules of how these materials form & help researchers control their synthesis.
#glycotime #chemsky

On behalf of the co-authors, we are happy to announce the publication of the new and updated #MIRAGE Reporting Guidelines for Mass Spectrometric Analysis of #glycans and #glycoproteins. 
🔗 https://tinyurl.com/mpnasrf8
#gylcotime #OpenAccess 🔓
 @flyglyco.bsky.social @pg-atlas.bsky.social @sib.swiss

Fusobacterium nucleatum Lipopolysaccharides O-Antigen Defines a Novel Siglec-7 Binding Epitope Fusobacterium nucleatum (Fn) is a Gram-negative bacterium predominantly found in the human oral cavity, occasionally linked to systemic diseases, including colorectal cancer. Bacterial lipopolysacchar...

F. nucleatum #LPS O-antigen engages #Siglec-7 through a previously unknown epitope, revealing how it may dampen immune responses in #CRC @robertamarchetti.bsky.social @molinarotony.bsky.social 👏 #glycotime #nmr #HostPathogen #Microbiome #Siglecs #microbiology #Glycans pubs.acs.org/doi/10.1021/...

21] Facts About: Intracellular Protein Glycosylation

🤯 Did you know proteins inside cells can be glycosylated?! 🔬 Our latest blog post dives into the surprising world of intra-cellular protein glycosylation & its vital role in biology!
👉 research.bidmc.org/ncfg/blog/21...

#glycans #glycosylation #posttranslationalmodification #glycotime

Glycoproteomics analysis of complement factor H and its complement-regulatory function during Streptococcus pneumoniae-associated hemolytic uremic syndrome - PubMed Hemolytic uremic syndrome caused by an invasive <i>Streptococcus pneumoniae</i> infection (SP-HUS) is a rare and severe disease that primarily affects children under two years of age. The…

Striking shifts in FH N-glycans appear in HUS patients without altering core function, raising big questions about whether AMD risk variants might also shape complement glycosylation. #AMD #complement #glycans #glycobiology #risk buff.ly/mPYgbVB

📢 Don’t forget to register!

Join Dr. @siglecdude.bsky.social and Dr. Edward Schmidt (University of Alberta) for a deep dive into new tools for studying Siglecs and their glycan ligands.

🗓 July 28 | 🕛 12 PM MST
🔗 canadianglycomics.ca/training/web...

#glycomics #Siglecs #glycans #glycoscience

Activity-Based Tracking of Glycan Turnover in Microbiomes Glycans shape microbiomes in the ocean and the gut, driving key steps in the global carbon cycle and human health. Yet, our ability to track microbial glycan turnover across microbiomes is limited, as...

#Glycans are central to the #carbon cycle.
Understanding their turnover in the ocean is key to ecosystem science.
In this paper: innovative chemical tools to trace glycans in complex marine microbiome.
#glycotime #chemsky

@mpimarinemicrobio.bsky.social
@unibremen.bsky.social
tinyurl.com/4x9h3v73

FEBS Press The H antigen (O blood group), the precursor to A and B blood groups, is expressed on human erythrocytes. Two novel monoclonal antibodies generated using sea lamprey immunization, Tn4-31L and OmcFL3-...

📢New article alert! 'Blood group O expression in normal tissues and tumors', just published in FEBS Journal, highlights findings using our lamprey-derived monoclonal antibodies towards specific H antigen epitopes.
Read at: febs.onlinelibrary.wiley.com/doi/10.1111/...
#glycotime #glycans #bloodgroups

#Glycoproteins #Glycolipids and #Glycans are critical components of #Immunity #TissueArchitecture #BiologicalProcesses

Magnefy™ Con A for easy magnetic isolation and depletion workflows.

See our latest product: bangslabs.com/product-cate...

#glycotime #lectins #glycans

GDP-fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP-fucose and fucosylated glycan synthesis

➡️ buff.ly/0h7HMY7

#Fucose #Glycans #Glycosylation

トップページ - Glyco-core Symposium 2025 Symposium Flyer Updated!

This year's Glyco-Core Symposium will be held at Nagoya University on September 24–25, 2025. Learn more and register: bit.ly/3ZEnX4z
🧪 #glycome #glycans #chemistry #metabolism #biochemistry #proteins #glycomics #glycoscience

New molecular label could lead to simpler, faster tuberculosis tests MIT chemists found a way to identify a complex sugar molecule in the cell walls of Mycobacterium tuberculosis, the world’s deadliest pathogen. This labeling could lead to simpler, faster TB tests.

New #molecular label could lead to simpler, faster #tuberculosis tests ...

| #TB | #Mycobacterium | #bacteria | #pathogen | #glycans | By @mit.edu via @eurekalert.bsky.social

ADAPTAM Therapeutics. The Next Era Of Cancer Immunotherapy. Adaptam Therapeutics brings better therapies to oncology patients thanks to immunotherapies that target the immunosuppressive myeloid tumor.

We are excited to support Adaptam’s mission to pioneer a new era of cancer #immunotherapy!

Learn more about Adaptam at: www.adaptamtx.com

#portfolionews #venturecapital #biotech #lifesciences #oncology #cancer #tumor #macrophages #glycobiology #glycans

preparing anhydrous solvent YouTube video by Peter Seeberger

#Carbohydrate Synthesis — fast, precise, and customizable.

Our scientists have found how to handle anhydrous solvents to ensure high-yield #glycosylation.

Learn how in this tutorial from the Automated #Glycans Assembly team led by @peterseeberger.bsky.social

www.youtube.com/watch?si=sUU...

Ou preprint is out! #Urobiome #OveractiveBladder #Glycans #Glycotime

Release Notes GlyCosmos Portal Release Notes

An update of GlyCosmos has been released today! You can see the release notes here doc.glycosmos.org/en/release-n... and minor releases are already planned for next week. #glycotime #glycans

🏆Alexander von #Humboldt Research Fellowship for Kazuki Inaba🏆

He plans to tackle 1of #glycoscience ’s biggest challenges: controlling #stereoselectivity

His envisaged #glycosylation method: donor sugars guide the synthetic process➡️ highly tunable #glycans as tools for research

#ChemSky

Neurons Unplugged: A Fun Journey Through the Brain's Social Network!

#Neuroscience #BrainFunction #Neurons #Synaptogenesis #Glycans #GutHealth #Neurotransmission #BrainAdventure #ScienceFun #LearnWithMe #Neurites #Mitochondria #BrainHealth #CognitiveScience

youtube.com/shorts/EfFMO...

SciTech Chronicles. . . . . . . . .Mar 26th, 2025 Strategy tells culture where to go. Culture tells strategy what's acceptable. Vol II No 77 535 links Curated The Deep Frontier of Mantle Mag...

SciTech Chronicles. . . . . . . . .Mar 26th, 2025

bit.ly/stc032625

#xenoliths #volatiles #subduction #models #spike #glycans #receptor #low-mutation ##Yellowknife #linear #dodecane #SAM #lipids #Mesoscale #signature #transport #photolysis #replenishment #size #thickness

SciTech Chronicles. . . . . . . . .Mar 26th, 2025 Strategy tells culture where to go. Culture tells strategy what's acceptable. Vol II No 77 535 links Curated The Deep Frontier of Mantle Mag...

SciTech Chronicles. . . . . . . . .Mar 26th, 2025

bit.ly/stc032625

#xenoliths #volatiles #subduction #models #spike #glycans #receptor #low-mutation ##Yellowknife #linear #dodecane #SAM #lipids #Mesoscale #signature #transport #photolysis #replenishment #size #thickness

17] Facts About: Two Tiny Glycolipids – Essential to Life

In the latest interesting facts about #glycans, we take a look at two tiny #glycolipids which are critical for life.

Read the full post at: research.bidmc.org/ncfg/blog/17...

For more interesting facts: research.bidmc.org/ncfg/interes...

#glycotime #glycofacts

🗞️The March Edition of GlycoNet news is out now! Catch up on:

🆕Glyco27 Early Bird Deadline March 21st!
🔬Job and research opportunities
🧪📄Recent publications and more!

Read now: mailchi.mp/6771a6144de7...

#glycotime #glycomics #glycans #newsletter #glycoscience

Novel enzyme breaks down and synthesizes previously unexplored glycans with prebiotic potential Carbohydrate chains, or glycans, are complex sugar-like compounds that play important roles in various biological processes and structures in our bodies. Galactosides are a type of glycan found in pla...

Novel #enzyme breaks down and synthesizes previously unexplored #glycans with prebiotic potential.

#mighymicrobes #Bacteroides #β-galactosidase #Bxy_22780 #α-GalF

phys.org/news/2025-03...

🔬 #Glyco27 Keynote Speaker 🔬

Dr. Hongzhi Cao (Ocean University) develops novel strategies for enzymatic & chemoenzymatic glycosylation. Catch his talk on chemical evolution of enzyme-catalyzed glycosylation!

📢 Register: www.glyco27.org/en/begin

@glycotime.bsky.social #glycoscience #glycans

A glycan that performs catalysis We reported a synthetic glycan sequence capable of catalyzing a chemical reaction. The design features an aromatic recognition site along with a reactive functional group connected via a folded glycan...

Artificial enzymes are based on proteins or RNA. But what if #glycans could also catalyze reactions & serve as #catalytic scaffolds?
Read in this blog post how @delbiancom.bsky.social created a glycan #foldamer that uses carbohydrate-aromatic interactions to perform #catalysis

tinyurl.com/mr25awkb