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Posts by Frédérique Le Roux

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The Social Lives of Viruses is coming to Vancouver, Canada, from 4th-8th August 2026!

This is a free meeting dedicated to all aspects of virus-virus interactions & evolution.

To apply: socialviruses.zoology.ubc.ca

@sociovirology.bsky.social #socialviruses #evosky #lovevirology #virosky

1 week ago 55 43 0 1

again a Science paper super easy to read that I will present to my students (as the ones on T6SS!), congrats again!

1 week ago 1 0 1 0

Congratulation Melanie!

1 week ago 0 0 0 0

Excited to share our new paper out today in @science.org 🎉

We show that HGT via natural competence drives diversification of chromosomal integrons in V. cholerae 🤩

Below a 🧵 on key findings incl. background on natural competence in V. cholerae 1/
#microsky #phagesky
www.science.org/doi/10.1126/...

1 week ago 212 85 11 2

Many thanks to @erc.europa.eu @agencerecherche.bsky.social Université de Montréal, Fondation Courtois, CERC, FCI; @cnrs.fr @pasteur.fr and yes I still eat oysters...

1 week ago 3 0 0 0

>1000 lytic vibriophages sequenced. 4 years later… still there. Same genomes. Same vibes. Different story. When nothing changes—but everything does. Congrats to Jeff & Karine et al. and @epcrocha.bsky.social for the intellectual turbulence ;-)
www.nature.com/articles/s41...

1 week ago 22 5 1 1

Finally, oysters serve as hotspots of horizontal gene transfer betw bacteria, mediated by mobile genetic elements. Which, considering the high density of bacteria in marine animals (rel. environment), could be quite general. Great work led by Jeff Liang, Karine Cahier. With @fredoleroux.bsky.social

2 weeks ago 4 1 0 0

Our ms on re-sampling 4 years apart vibrio phage in natural environments is now out with some improvements. First, clearer evidence of cryptic population dynamics between phage and vibrio, presumably because of genetic diversity. www.nature.com/articles/s41...

2 weeks ago 49 21 1 0
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Immune-deficient bacteria serve as gateways to genetic exchange and microbial evolution Nature Communications - The efficiency of horizontal gene transfer between different bacterial lineages is often unclear. Here, Figueroa et al. show that lateral transduction is the primary driver...

Latest from the lab!
Between clinical S. aureus, most gene transfer mechanisms are blocked, yet lateral transduction remains highly efficient.
Restriction modification-defective strains act as gateways for horizontal gene transfer, enabling DNA flow across populations. rdcu.be/fbNQK

2 weeks ago 29 17 0 0
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Lundi 9 mars, 12H, évènement CERC Le Roux/decanat UdeM, journée internationale de la femme. Projection documentaire et débat "sur la libération de la parole et de l'écoute de personnes ayant vécu de l’oppression basée sur le genre." Pavillon Jean-Brillant – Salle B-0245 . Inscription avant 2 mars.

2 months ago 0 0 0 0

Armes puissantes contre la culture du silence, les médias ont permis à des voix restées longtemps mutiques ou étouffées d’être entendues et d’exprimer une somme impressionnante de colères et de désirs" - Caroline Pierret

2 months ago 0 0 0 0

Plus jamais silencieuses est une installation vidéographique documentaire et participative dont le propos est centré sur la libération de la parole et de l'écoute de personnes ayant vécu de l’oppression basée sur le genre.

2 months ago 0 0 0 0

Projection du documentaire "Plus jamais silencieuses" de Caroline Pierret
Organisée par la CERC de Frédérique Le Roux, professeure titulaire au @Département de microbiologie, U de M - , en collaboration avec le vice-décanat à la recherche et au développement

2 months ago 0 0 0 0

www.facebook.com/medecine.umo...

2 months ago 0 0 3 0

Seeking expressions of interest from researchers abroad for a Canada Impact+ Research Chair ($1M/year × 8 + up to $6M CFI) in AI-enabled antibiotic discovery and/or AMR, phage & phage-based derivatives. Email me a short vision, CV, and 3–5 key papers. Deadline: March 10, 2026 (Intake 2: June 15).

3 months ago 6 11 0 0
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Une piste prometteuse pour augmenter l’efficacité des antibiotiques Les aminosides sont des antibiotiques efficaces contre de très nombreuses bactéries telles que Escherichia coli, Pseudomonas aeruginosa ou Staphylococcus aureus. Mais jusqu’à présent, personne ne sava...

🦠💊 L’Institut @pasteur.fr vient de publier un communiqué de presse sur nos récents travaux, qui décrivent une nouvelle piste pour augmenter l’efficacité des antibiotiques. #Pasteurdon #Recherche #Science #AMR

Merci à toutes celles et ceux qui ont contribué.

📘 English version coming soon!

5 months ago 28 16 0 1
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Many thanks to all those involved, including Jeffrey Liang, who stayed in our lab for several months, our own Charles Bernard and, of course, @fredoleroux.bsky.social and the usual suspects @agencerecherche.bsky.social @erc.europa.eu @cnrsbiologie.bsky.social @pasteur.fr @umontreal.ca etc

6 months ago 3 1 0 0

Two intensive sampling periods of oyster-associated vibrio and their phage, 4 years apart, and many surprises. Despite being washed by the Atlantic, wide tides, and vibrio (almost?) disappearing most of the year, we can find the exact same virulent phages 4 years later (down to 0 SNP)! preprint👇

6 months ago 39 19 1 1
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Ecological constraints foster both extreme viral-host lineage stability and mobile element diversity in a marine community Phages are typically viewed as very rapidly evolving biological entities. Little is known, however, about whether and how phages can establish long-term genetic stability. We addressed this eco-evolut...

Phages evolve fast, or do they?
In oysters, some stay identical for years.
With >1,200 phages & 600 Vibrio genomes, we reveal long-term stability and new mobile elements.
Proud of this collaborative work across our teams (Roscoff-UdeM and @epcrocha.bsky.social www.biorxiv.org/cgi/content/...

6 months ago 89 50 1 2
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Chimeric infective particles expand species boundaries in phage-inducible chromosomal island mobilization Capsid-forming PICIs (cf-PICIs) produce their own capsids and exploit phage tails from unrelated species to transfer their DNA across bacterial hosts. This tail piracy enables broad dissemination and ...

Thrilled to share our two latest papers with the @tcostalab.bsky.social
lab! In the first, we uncover a new mechanism of satellite transfer: cf-PICIs hijack tails from diverse phages to spread across species.
@imperialcollegeldn.bsky.social
www.cell.com/cell/fulltex...

7 months ago 99 50 0 6
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Chimeric infective particles expand species boundaries in phage-inducible chromosomal island mobilization Capsid-forming PICIs (cf-PICIs) produce their own capsids and exploit phage tails from unrelated species to transfer their DNA across bacterial hosts. This tail piracy enables broad dissemination and ...

Chimeric infective particles expand species boundaries in phage-inducible chromosomal island mobilization: Cell www.cell.com/cell/fulltex...

7 months ago 5 2 0 0
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The ecology and evolution of microbial immune systems: a look on the wild vibrio side | Philosophical Transactions of the Royal Society B: Biological Sciences Natural populations of vibrio beyond the well-studied pandemic strains of Vibrio cholerae, provide a powerful model for investigating the eco-evolutionary dynamics of microbial immune systems. Their genetic diversity, ecological versatility, ease of ...

The ecology and evolution of microbial immune systems: a look on the wild vibrio side

Phil. Trans. R. Soc. B by @fredoleroux.bsky.social

royalsocietypublishing.org/doi/10.1098/...

7 months ago 15 6 0 0

And thank you so much Pauline!!! It was very cool to see you again with other 'old' conference friends, looking forward to see you again @ Roscoff 2026/Monod conference/virus evolution ;-)?

8 months ago 2 0 0 0
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SCM-CSM2025 UMontreal Conference Fourwaves - SCM-CSM2025 UMontreal Conference

and here is the link for the program: event.fourwaves.com/fr/scm-csm20...

10 months ago 0 0 0 0
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👉 Next stop: Montréal! 🇨🇦 Thrilled to join the Canada Society of Microbiology (CSM) conference, June 17-20. Science, community, and reconnecting with old friends — can’t wait!

10 months ago 7 2 2 0

The study involves our‪ microbiologist @fredoleroux.bsky.social, whom we profiled in late 2023 as a new hire and Canada Excellence in Research Chair: nouvelles.umontreal.ca/en/article/2...

10 months ago 11 5 0 0
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Allo Montreal, 11 juin –18H au café La brassée:
"Des sphères aux spirales, des extrémophiles aux probiotiques: plongez dans l’univers fascinant des bactéries ! "
Appéro- Science, qui dit mieux? #cinqascience #5ascience

10 months ago 1 1 0 0
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commemorating pride from the clinical microbiology lab

10 months ago 56 13 1 0
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How clonal are bacteria over time? Bacteria and archaea reproduce clonally (vertical descent), but exchange genes by recombination (horizontal transfer). Recombination allows adaptive m…

And I've written a few reviews on the subject over the years, but this one is pretty short, so why not start there ;)

www.sciencedirect.com/science/arti...

10 months ago 15 4 1 0
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Allo Montreal, 11 juin –18H au café La brassée:
"Des sphères aux spirales, des extrémophiles aux probiotiques: plongez dans l’univers fascinant des bactéries ! "
Appéro- Science, qui dit mieux? #cinqascience #5ascience

10 months ago 1 1 0 0