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Posts by Alejandro Montenegro

Hi! Is Berlin part of the Germany tour too? 😊

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Time Is Finite In this narrative medicine essay, a psychiatrist and residency program director discusses how her lung cancer diagnosis caused her to shift her priorities regarding work and home life.

Time is finite, & we should prioritize and value things accordingly.

Quotes from a recent editorial at JAMA:

"The meaning of my work is profound. The meaning of my presence at home is irreplaceable."

"The people who love us need us as ourselves. And that is the role no one else can fill"

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I meant the CD as a whole

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Yes! I think the point is just that some theoretical grounding was needed to move things forward. And I think it was successful 😊

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As Crick wrote, "the discovery of just one type of present day cell which could carry out any of the the unknown transfers would shake the whole intellectual basis of molecular biology, and it is for this reason that the central dogma is as important today as when it was first proposed"

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In any case, it's important to remember that the CD was just a theoretical framework; something put together when we knew very little, which was useful for stating problems clearly and thus guiding experiments. If we do find things that "break" it, great!

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Also, it's not about "protein synthesis" per se; it's about the residue-by-residue transfer of sequential information.

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It's great when authors see the light 😊

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Regardless, it still needs to be correctly understood, though.

And that is what's typically missing when calling its demise.

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BTW...

www.barrons.com/articles/ai-...

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BTW...

www.barrons.com/articles/ai-...

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I’m much less sure about where to submit my papers than I used to be Way back in 2013, I wrote advice on how to decide which journal to submit to. Now I want someone else to give me advice on that! It used to be that I was always quite sure about where to submit my …

"I still don’t care if the paper will be paywalled or not. That is, I’ll pay for open access publication if I have the funds and the journal is otherwise a good fit for the paper, but I don’t care about open access per se"

dynamicecology.wordpress.com/2026/04/15/i...

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In Neurospora crassa.

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Correct.

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Always an important point

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Refreshing to see everyone talking about how cool a research finding is instead of whether the paper was OA or not (nb. It wasn't)

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TAD boundaries and gene activity are uncoupled Single-cell analysis fails to find a functional link between the organization of chromatin domain organization and gene activity.

"We find that while TAD boundaries pair more frequently than non-boundary regions, these interactions are infrequent and are uncorrelated with transcriptional activity of genes within the TAD"

elifesciences.org/articles/110...

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Right. So, just as easily as that came (via funder mandates), it could go away.

If the goal is just to have a version that can be freely accessed, funders could just require that a preprint is made available.

www.nature.com/articles/d41...

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Or if acknowledged, which doesn't necessarily have to be publicly

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Rings a bell 👀

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It's easy to say that something is wrong when you didn't take the time to actually read it or understand it.

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"A truly general biology, is an evolutionary biology"

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No

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LOL no! It's just that I'm looking for a very specific thing

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I'm looking for #NewPIs (<3 years as lab heads) in the gene regulation/functional genomics space. If you are one or know one, please comment below! 🧪

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a woman wearing a red shirt with the word blasphemy written on it ALT: a woman wearing a red shirt with the word blasphemy written on it
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It is but it shouldn't *exclusively* be (institutions should play a way more active role monitoring what is submitted under their name), and yes, there are funds. My point was mostly that publishing, and doing it well, costs money. And when asking for more services... 🔽

bsky.app/profile/aemo...

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And all of this takes money and resources. And time.

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