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Posts by Martin Vögele

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Wildlife sculptures built from more than 1.5 million Lego bricks are part of the stunning exhibition "Brick Planet" by Sean Kenney.

#LEGO #BrickPlanet #Wildlife #Museum #LegoArt #ArtPhotography

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HarvardX: American Government: Constitutional Foundations | edX Learn how early American politics informed the U.S. Constitution and why its promise of liberty and equality has yet to be fully realized.

Harvard University is offering a free online course on the U.S. Constitution, taught by my friend and mentor Thomas Patterson. Understanding our Constitution has rarely been more important. Here's how you can enroll. www.edx.org/learn/govern...

1 week ago 83 42 1 0
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... and fascinating contemporary art during the Whitney Biennial.
#NewYorkCity #ArtPhotography #WhitneyBiennial #ContemporaryArt

3 days ago 1 0 0 0
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The Whitney Museum offers great views of the city...

3 days ago 1 0 1 0
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Downtown Denver in front of the Rocky Mountains.

#Denver #Colorado #RockyMountains
#Photography 📷

5 days ago 8 0 0 0
Science | AAAS

I guarantee that you have not considered this method of CNS drug delivery!

6 days ago 32 7 4 2
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How Silicon Valley Is Turning Scientists Into Exploited Gig Workers Tech elites are enriching themselves by plundering STEM institutions—and offering researchers scraps.

“Silicon Valley would not exist without [taxpayer-] funded research.”
www.thenation.com/article/soci...

6 days ago 150 59 2 7
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Catching Pet Infections Earlier with DNA‑Based Rapid Tests When our pets get sick, having the right answers sooner can make all the difference. A recent study explores a more sensitive rapid test that could one day support at‑home screening for common pet…

When our pets get sick, having the right answers sooner can make all the difference. A recent study explores a more sensitive rapid test that could one day support at‑home screening for common pet infections.

Read more on ACS Axial: buff.ly/8AdIt13

1 week ago 1 1 0 0
Model of a sauropod heart.

Model of a sauropod heart.

Model of a sauropod head.

Model of a sauropod head.

Model of a sauropod lung and ribcage.

Model of a sauropod lung and ribcage.

The exhibition "The World’s Largest Dinosaurs" at the Denver Museum of Nature and Science shows life-size models of the anatomy of sauropods, the largest land animals to ever live.

#Dinosaurs #Anatomy
#Denver #Colorado
#Photography 📷
#Science 🧪

1 week ago 11 2 0 0
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Downtown Flushing in Queens.
#Photography #NewYork #NYC

1 week ago 7 0 0 0

Exploiting internal symmetry can be a powerful approach to analyse convergence in MD simulations.

If two conformational states are symmetry related, their kinetic and thermodynamic properties should be the same. If one doesn't enforce this during analysis this provides a useful test. 1/n

1 week ago 21 7 1 0
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The facade of the hotel Populus in Denver was inspired by the dark lenticels found on the bark of quaking aspen trees. The hotel claims that it achieves net negative carbon dioxide emissions.
#Denver #Colorado #Architecture #Photography #Environment

1 week ago 12 4 0 2
Figure 1. Cryo-EM of abundant protein complexes in native membranes.

Figure 1. Cryo-EM of abundant protein complexes in native membranes.

Figure 2. Cryo-EM of membrane proteins in vesicles.

Figure 2. Cryo-EM of membrane proteins in vesicles.

Figure 3. 3D reconstruction of V-ATPase in native synaptic vesicle membranes.

Figure 3. 3D reconstruction of V-ATPase in native synaptic vesicle membranes.

Figure 4. Generation of membrane vesicles for structure determination of proteins in their native lipid bilayer.

Figure 4. Generation of membrane vesicles for structure determination of proteins in their native lipid bilayer.

I've written a review on what I think is an extremely exciting direction in cryo-EM:

Cryo-EM of endogenous membrane proteins in their native lipid bilayer

Open access in Quarterly Reviews of Biophysics:
doi.org/10.1017/S003...

1 month ago 173 65 3 2
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Hallucinated citations are polluting the scientific literature. What can be done? Tens of thousands of publications from 2025 might include invalid references generated by AI, a Nature analysis suggests.

Hallucinated citations are polluting the scientific literature www.nature.com/articles/d41... ...I call these hallucitations

2 weeks ago 11 4 0 0
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The Colorado State Capitol Building
#Photography #Denver #Colorado

2 weeks ago 13 2 0 0
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Our new book chapter has just been published! "Computational approaches for protein complex modeling for intermediate resolution cryo-EM maps" We introduced our recently developed tools available on the EM server (em.kiharalab.org).
You can read it here:
www.sciencedirect.com/science/chap...

2 weeks ago 10 3 0 0
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A thought about job adverts. I assume seeking "exceptional" individuals selects for specific character traits (eg self confidence). My goal is to get candidate with best potential, even if they don't yet think of themselves that way. What words do you use to encourage the widest pool of applicants?

3 weeks ago 13 5 2 1
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Humans Had Dogs Before They Had Farming, Ancient DNA Confirms

Dogs have been our friends for a very long time. 🐶

NYT gift link:
www.nytimes.com/2026/03/25/s...

3 weeks ago 8 3 2 0
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Downtown Denver at Night.
#Photography #Denver #Colorado #NightPhotography #CityLights

3 weeks ago 9 0 0 0
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Exciting to see the approval of linerixibat for cholestatic pruritus—an IBAT inhibitor that targets the underlying bile acid biology driving itch.

A great example of basic science translating into real therapies. Curious to see where IBAT inhibitors go next.

3 weeks ago 3 1 1 0
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Episode 32 - Robert Best, Sonya Hanson, Xuhui Huang: Driving the Future of Biophysics. What’s Next in Theory and Computation? - Phase Space Invaders (ψ) With the convergence of data, computing power, and new methods, computational biology is at its most exciting moment. At PSI, we're asking the leading researchers in the field to discover where we're ...

Celebrating #BiophysicsWeek T&C partnered with Phase Space Invaders podcast: Robert Best @sonyahanson.bsky.social @xuhuihuangchem.bsky.social and host @milosz-wieczor.bsky.social Episode 32: Driving the Future of Biophysics: What’s Next in Theory and Computation?
www.buzzsprout.com/2313153/epis...

3 weeks ago 11 7 0 2
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Evolution seems to have repeatedly converged on a similar architecture in the early olfactory system of many animals. We offer an efficient-coding framework to understand this. Out in @pnas.org now! Led by @jzv.bsky.social, driven by Juan Carlos, + help from Farhad. www.pnas.org/doi/10.1073/...

4 weeks ago 47 19 0 1
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Computer-aided structural modeling and drug discovery for G-protein-coupled receptors in the age of artificial intelligence G-protein-coupled receptors (GPCRs) are a large family of membrane proteins that mediate cellular responses to diverse stimuli and serve as targets fo…

Nice read: a mini-review by Novack & Filizola on #AI in #GPCR #DrugDiscovery.
Summarizes well where AI is actually helping and where it is not yet reliable. Current main limitations: active states, flexible regions, transient interfaces, and interpretability.
www.sciencedirect.com/science/arti...

3 weeks ago 8 3 0 1
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Welcome to allergy season. Here's how to protect yourself Allergy season is upon us, bringing with it runny noses, itchy eyes and sneezing. Climate change is leading to longer and more intense allergy seasons.

Allergy season is upon us, bringing with it runny noses, itchy eyes and sneezing.

4 weeks ago 55 18 0 2
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I wonder: How were the plates aligned? Rotation symmetry would make that pretty arbitrary, no?

4 weeks ago 1 1 1 0
Left: Banner announcing the APS global physics summit in Denver. Right: The Daniels & Fisher Tower in bright sunlight.

Left: Banner announcing the APS global physics summit in Denver. Right: The Daniels & Fisher Tower in bright sunlight.

It's a wrap! hard to believe so much science could fit in a single week. Also going by the weather, this conference lasted an entire season; it started with wintery snow and is ending with scorching sunshine.
#APSSummit26

1 month ago 2 1 0 0
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Elasticity of the HIV-1 core facilitates nuclear entry and infection Author summary The genetic material of HIV-1 is packaged inside a cone shaped container that is called the viral core. To infect a cell, the viral core must pass through the cell’s nuclear pore. Using...

On the last day of the APS Summit, I am following physical virology talks.

Juan Perilla introduced us to the mechanobiology of viral capsids and presented his investigations into the effect of Cyclophilin-A on the HIV-1 capsid using simulated AFM.
www.biorxiv.org/content/10.6...
#APSSummit26

1 month ago 1 0 1 0
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Extreme dynamics in a biomolecular condensate - Nature Two highly charged disordered human proteins phase-separate into viscous complex coacervates while retaining their rapid conformational dynamics through pico- to nanosecond exchange of short-lived sid...

Finishing the day with biomolecular condensates. #APSsummit26

Ben Schuler presents an impressive combination of simulation and experiment. Important insight: The microscopic dynamics of polyelectrolytes can be connected to their bulk viscosity via polymer physics.
www.nature.com/articles/s41...

1 month ago 5 2 1 0
text that reads: We're hiring! Software Engineer, MESA

text that reads: We're hiring! Software Engineer, MESA

#FlatironCCA is seeking a research software engineer to develop, maintain, and contribute to community-oriented software instrument tool MESA (Modules for Experiments in Stellar Astrophysics). See more: https://apply.interfolio.com/182988 #science #astrophysics #hiring

1 month ago 2 4 0 0
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2026 ISQBP President’s Meeting breaking barriers with the computational microscope

Considering joining us at the 2026 International Society of Quantum Biology and Pharmacology (ISQBP) meeting. June 15-16, 2026 in Cluj-Naoca, Romania.

isqbp2026.com

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