Helicobacter pylori induces the production of interleukin-37 to promote broad immunosuppression and enhance colonization Helicobacter pylori infects approximately half of the world’s population, resulting in lifelong gastric infections. To promote lifelong colonization, H. pylori modulates host immunity via unknown m...

New Study: Helicobacter pylori induces epithelial interleukin-37 to suppress and evade host immunity and enhance bacterial colonisation and pathogenesis.

Fantastic collaboration between the Liaskos and Nold labs
@thedohertyinst.bsky.social
@hudsonresearch.bsky.social

Going great thanks, I hope all is well with you

Love this article Jenny! Would be amazing to understand how much diet can influence distal SCFA concentrations and benefits beyond the gut particularly in protection against UTI or even how specific urinary targeting SCFA-containing therapeutics could have clinical benefits

@christophermccrory.bsky.social from @thedohertyinst.bsky.social explains how H. pylori leverages membrane vesicles for horizontal gene transfer.

Incredible insights into microbial survival strategies!

🦠🧬📩

Really happy to see this work out!

Super fun project with a great team. For me the highlight was that we finally were able to show the O-linked glycosylation systems of H. pylori/C. jejuni are general glycosylation systems which target non-flagellin proteins (suggest >10 years ago by click chem).

Uncovering bacterial pseudaminylation with pan-specific antibody tools - Nature Chemical Biology Pseudaminic acids (Pse) are a family of carbohydrates found within bacterial lipopolysaccharides, capsular polysaccharides and glycoproteins. Now, monoclonal antibodies have been developed that recogn...

Monoclonal antibodies against pseudaminic acid (Pse) – present in bacterial LPS, capsular polysaccharides, and glycoproteins – have been developed that enable Pse glycoproteome profiling and show therapeutic potential #glycotime

www.nature.com/articles/s41...

Christopher McCrory christophermccrory.bsky.social
from the @thedohertyinst.bsky.social explaining his work on the role of bacterial membrane vesicles conferring anti-microbial resistance in H.pylori

#YoungVIIN2025 #VIINYIS

Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host - Nature Microbiology A mycovirus infecting the pathogenic fungus Aspergillus fumigatus enhances its stress tolerance and virulence in mice.

🚨 Fungi + viruses + mammalian lungs? Buckle up! Our new paper in
@natmicrobiol.nature.com
uncovers the story of a deadly fungus and its gnarly viral hitchhiker — and how this duo may change how we diagnose & treat fungal disease 🍄🫁🚨 doi.org/10.1038/s415... ⬇️

A fungus that can ‘eat you from the inside out’ could spread as the world heats up | CNN Infection-causing fungi responsible for millions of deaths a year will spread significantly to new regions as the planet heats up, new research predicts —and the world is not prepared.

edition.cnn.com/2025/05/24/c...

Is pathogen prediction possible? To what extent can we predict future pathogenic microbes? This Perspective discusses why complex requirements for virulence and dynamic host-microbe interactions make probabilistic predictions difficu...

To what extent can we predict future pathogenic #microbes? @acasadevall1.bsky.social discusses why probabilistic predictions are difficult, but not impossible. 🧪
plos.io/3EXieQp

Fungal infections are ‘taking over the world’. Can they be stopped? As a landmark WHO report warns of a lack of treatments and diagnosis, we investigate a threat that now kills twice as many people as TB

www.telegraph.co.uk/global-healt...

Deadly fungi are becoming drug-resistant. A new compound could beat them A drug candidate with a new mechanism of action shows promise against several drug-resistant infections in mice

Deadly #fungi are becoming drug-resistant. A new compound could beat them | Science | AAAS www.science.org/content/arti...

What is Antimicrobial Resistance (AMR)? - The AMR Narrative YouTube video by The AMR Narrative

Antimicrobial Resistance #AMR is a term most people have never heard of before yet it's a global health crisis

Our charity, #theAMRnarrative has created a 90-second explainer video to help you grasp the basics

youtu.be/S_0XQ5LhA6o?...

#AntibioticResistance
#AntimicrobialResistance #GlobalHealth