Happy International Day of Women and Girls in Science to the incredible women at WSIC! 🕵🏻♀️💆🏻♀️👩🏻⚕️👩🏻🔬👩🏻🎓💗Your curiosity drives discovery and your work inspires us all. Here's to asking the big questions and finding the answers! 🧪✨ 🔬#WomenInScience #WSIC #FemaleScientists
Posts by Werner Siemens Imaging Center
🔬New preprint on predicting immunotherapy response using functional imaging 🩻
NF-κB luciferase reporter mice reveal that NF-κB activation in the tumor microenvironment-but not resistant tumors-correlates with effective combo immunotherapy.
👉 doi.org/10.21203/rs....
🎄 Festive cheer in the lab!🌌
On Monday evening, we gathered for our annual Christmas party, celebrating the end of a busy and productive year.
A special thank you to our office team for all the hard work they put into planning this party 🎉
🎓👏We congratulate Dr. Dr. Salvador Castaneda Vega on successfully defending his thesis:
“Exploring the role of G-proteins and the erythropoietin receptor in ischemic stroke.”
We are incredibly proud of his hard work, dedication, and scientific impact.
Well done Dr. Dr. Salvador Castaneda Vega 🎉
Making the detectors for your PET insert DOI-capable can improve your spatial resolution. But have you ever wondered how that affects your other performance metrics?
We have quantified the effects for several cases suitable for breast & brain PET/MRI inserts!🩻☢️
🔗 ieeexplore.ieee.org/document/112...
🎓🚀Huge congratulations to Dr. Simon Isser on the successful defense of his PhD!
His remarkable work on “Molecular Imaging of Pulmonary Fibrosis” opens new paths in understanding and visualizing lung disease. 🔬🫁
An incredible achievement after years of dedication! Well done, Simon! 👏✨
Last week, four of our PhD students joined GyMIC in Göttingen — a vibrant gathering of young molecular imaging researchers! They connected with peers, shared experiences, and came back with fresh ideas and inspiration 🧬🤝
We’re thrilled that our researchers will present on microbiota-derived metabolites in cancer 🧫⚛️ at two meetings!
🇩🇪 Munich Metabolomics Meeting –
🗣 @sissid.bsky.social (Oct 10, 11:20)
🇨🇭 Swiss Metabolomics Society – Oct 10
🗣 Christoph Trautwein (14:40)
🔗 swiss-metabolomics.ch
👏 Good luck to both!
Greetings from Hannover! 🇩🇪
Our colleague Dr. Christoph Trautwein presents at the German Society for Metabolomics 🧪🧬 Talk: Multimodal metabolomics (NMR, timsTOF LC-MS, MALDI Imaging) in cancer 📅 Oct 2, 9:00–9:15 #Metabolomics #CancerResearch
Exciting science at #IMSIS2025! 🌟🇺🇸 Our colleague @sissid.bsky.social will present on multimodal metabolomic profiling to uncover biomarkers & pathways in endometriosis. 📍UC Davis, Sep 30, 13:30. Don’t miss insights into mass spectrometry imaging & women’s health! #Endometriosis #Metabolomics
First day of our 5th Day of Intravital Microscopy conference has started!
Organised by our Team Intravital Microscopy and the working group of the @wsic.bsky.social and iFIT Cluster of Excellence.
Already had amazing talks and are looking forward to many more ✨
#IvMic2025
🎓✨ Congratulations to Dr. Federica Bonanno on her successful defense! 👏
Her thesis, “Development and Radiolabeling of Structurally Distinct Pyrazolethiazole PET Tracers for Imaging of Alpha-Synuclein Aggregates”, marks an important step forward in molecular imaging of neurodegenerative diseases🧠🔬
Happy to share that our PhD Student Ragini Kushwaha will be presenting at the 7th UK Preclinical Stroke Symposium at Keble College, University of Oxford 🇬🇧✨
Title: “The role of Gai proteins in neutrophils and platelet-neutrophil complexes during ischemia reperfusion injury”
🗓️ Today ⏰ 11:30–11:45
Still feeling inspired after our time at TOPIM 2025 in Siena🇮🇹
We are excited for the work happening in theranostics 🧬💉
Congrats to Grace Mayuni for the Poster Award 🏆 and to Dimitri Stowbur as part of the winning Red Team👏
And of course, a huge thank you to the ESMI for their organizing work!
Day 2 at #TOPIM2025 🇮🇹✨
🧬 Grace Mayuni presenting her poster on enzymatically radiolabeled scFv fusion proteins (Poster Pitch II, Tue 16:30)
🎤 Dr. Dimitri Stowbur on L-DOS47 & the tumor microenvironment (Wed 17:15)
🦠 Marc Neumann on oncolytic virus therapy & ICI-based immunotherapy (Wed 17:35)
Hello from Siena 🇮🇹!
The WSIC is at TOPIM 2025 – "Theranostics: Pushing the Limits"
Kicking off our line-up, Francisco Reche-Pérez will present:
🗣️ Next-generation β-galactosidase targeting senescence radiotracers☢️💉
📅 Tue, Aug 26 | 17:35–17:50
Stay tuned for more from our team!
📰New Paper📰!
Our study: "PET-based immunomapping of intratumoral CD4⁺ cells to monitor acquired resistance to checkpoint inhibitors,☢️💉"
We present a non-invasive PET approach to map CD4⁺ T cells in tumors & track resistance to immunotherapy🧬.
🔗 www.science.org/doi/10.1126/...
WSIC Lab Celebrates Summer & Success!⛱️🍹
Cheers to our amazing team for a memorable #summerparty ☀️
Congrats to our 2025 awardees:
🏆 Dr. Laura Kuebler – Best Thesis
🍾 Marilena Poxleitner – Best Publication
🥇 Yasmin Al-Moufleh & Adrian Mannel -winner chefs of our food contest!🌮🍜
🗞️New paper!!
🧊Cryogenic tissue pulverization + lyophilization as a tool for multi-omics from a single mouse biopsy 🧬🧪
Takeaways:
✅ Preserves molecular integrity
✅ Reduces biological variability
✅Single sample multi-omics
🔗 www.nature.com/articles/s41...
Congrats to @laimziz.bsky.social & team🎉
What an event!
Huge thanks to the organizers and everyone who stopped by to chat and exchange ideas. I’m always excited to bring open, accessible conversations to non-scientific audiences - breaking down the barriers of complex science and medicine.
Truly enjoyed every moment! 😎
@wsic.bsky.social
🧪 We are happy to share a recent study by Gyuntae Bae and our #metabolomics team - using NMR spectroscopy and inflammatory profiling in long #Covid-19🫁 —reveals a persistent hyperlipidemic signature alongside low-grade progressive inflammation.
More info here🔗 link.springer.com/article/10.1...
Latest work by Georgy Berezhnoy and members of our metabolomics team 👏
🧠 Highlights:
• Stratified Parkinson's Disease by genetics (e.g. GBA), duration, and severity
• Identified potential biomarkers
• Linked metabolite patterns to dementia with Lewy Bodies
🔗: www.nature.com/articles/s41...
🧬New paper!
@sissid.bsky.social & co-authors explored microbiota-derived metabolites in ascites from ovarian and GI cancer patients. With 4D #metabolomics, they found shared profiles in advanced disease and links to immune markers like IL-10.
🔗 cancerandmetabolism.biomedcentral.com/articles/10....
WSIC at the 17th SEeON Conference✨
This morning, Eden Laing will be giving a talk on her PhD work!
🕘 9:45–10:45 | Session on Gut Microbiota Recovery
Eden’s work showcases innovative approaches at the intersection of imaging and microbiome research🔬🧪🦠
✨Don’t miss it!
#SEeON2025
🧪 Day 2 at #Metabolomics2025 in Prague 🇨🇿!
Check out Poster Group B (June 24–25):
@sissid.bsky.social -P2058B: NMR + MALDI reveal metabolic heterogeneity in endometriosis
Gyuntae Bae – P2059B: Lipidomics + cytokines uncover post-COVID inflammation
Come meet our PhD students behind the science!
🎉 Heading to #Metabolomics2025 in Prague!
Join us Mon (June 23) at the Welcome Reception & Tues (June 24) A.M. break/lunch.
📍#1063A – Dr. Christoph Trautwein: NMR in solid cancers
📍#1074A – @laimziz.bsky.social : Tumor microenvironment via spatial metabolomics
#NMR #CancerResearch
🎉 Some exciting news!
Our PhD student, Remy Chiaffarelli's abstract for #ISMRM2025 scored in the top 5% — earning him a special award🎖️— and was also selected by the Annual Meeting Program Committee (AMPC) for further recognition.
Congratulations Remy👏
@ismrm.bsky.social
Gina Dunkel from our department will be presenting a poster at #EACR2025!🇵🇹
The congress brings together researchers from all over the world to share breakthroughs in cancer research. If you’re there, don’t miss it!
2025.eacr.org
#EACR2025
🧠 Just published: our latest paper explores why great segmentation doesn't always equal accurate therapy detection in stroke research. Key finding: Training nnU-Net with probabilistic GMM labels boosts therapy response accuracy.
Dive in 👉 www.sciencedirect.com/science/arti...
#AI #StrokeResearch
Greetings from South Korea🇰🇷!
Proud to share that two of our members are presenting their work at the 🧠Brain & Brain PET 2025 conference in Seoul!
Coming up, Prof. Dr. Kristina Herfert will present on - "Functional dynamics through a molecular lens: Imaging connectivity in preclinical models".