Certainly an area of research I am keen to participate in! Enlightenment credit to Dr Jess Green and SVH Grand Rounds.

@cindyclau.bsky.social but what about increased linezolid doses???
#DDIs, #obesity ???
Some case studies in patients with respiratory infections/ ARDS suggest different oxidative pathways and up regulation of CYP expression that may influence #linezolid concentrations #antimicrobials2025

@cindyclau.bsky.social
#linezolid does one dose fit all????
Most likely not! Dr Cindy Lau goes through some scenarios - elderly, renal and hepatic impairment, #DDIs - where dose reductions may be warranted to improve patient care (& reduce toxicities)
#antimicrobials2025 #IDsky #amssky

Seems the perfect first post and start to Antimicrobials 2025; thank you to the brilliant @erinmccreary.bsky.social for a great opening plenary (but please get out of my head 😉) #linezolid #cefepime