Nationally there are a range of programs/pilots!
Next steps are
- national harmonisation where possible!
- improved education
- further scaling for other conditions
👏🏽 👏🏽 👏🏽
#antimicrobials2025 #idsky #amssky
Dr Kylie McIntosh Safer Care Victoria providing updates on the Victorian pilot of pharmacist led UTI management, implications on #AMS and the critical need to #upskill #communitypharmacists
#antimicrobials2025
#pharmacysymposium #IDsky #AMSsky #UTI
A/prof Daniel Capurro
#generativeAI models have evolved so much already in the last 15 months in the quality of responses to a clinical scenario prompt! Much more granular detail and recommendations!
#AI #amssky #idsky #antimicrobials2025
#Sorrynotsorry to all our ID dra who have side hustles in martial arts& stand up comedy! Very low probability u are good at this as per #generativeAI
A/Prof Daniel Capurro-Centre of Digital Transformation of Health always providing easy explanations 4 us learning about #ML & #AI #antimicrobials2025
We can’t forget about our patients! #allergydelabeling can improve #QOL with more work to be done to further support these findings
#antimicrobials2025
#amssky #idsky
@elisemitri.bsky.social
#PENFAST. But what’s next?
#SULFAST and #CEPHFAST
Evidence and validation underway but need implementation strategies to ensure program success!!!!! #hybridimplementationtrials
@elisemitri.bsky.social
#antimicrobials2025
@elisemitri.bsky.social highlights the evidence and what’s next in antimicrobial allergies - lots happening in this space #antimicrobials2025 #AMSsky
@elisemitri.bsky.social summarising key literature supporting low risk antibiotic allergy research across various settings with various prescribers. Highlighting the importance of multidisciplinary approaches and that antibiotic allergy is relevant to all settings!
#antimicrobials2025 #idsky #amssky
@elisemitri.bsky.social
Leading Aus #Ams pharmacist in penicillin allergy delabeling highlighting the importance of #implementation science to ensure the success of interventional allergy delabeling programs& how the narrative has changed and progressed over the last 20 years
#antimicrobials2025
A/Prof Sophie Stocker showcases the various models and methods for biosensors and there roles for #TDM and #precisionmedicine
#pkpdmodels
Many drugs are still in animal trial phases
#antimicrobials2025 #IDsky #AMSsky
Great speakers @michyong.bsky.social @cindyclau.bsky.social in the @ausantibiotics.bsky.social #antimicrobials2025 pharmacy symposium where Q&A sessions are turning into patient consults sessions 😉
Consider linezolid dose reduction in the following - elderly, renal impairment, hepatic dysfunction, concomitant clarithromycin @cindyclau.bsky.social #antimicrobials2025
@cindyclau.bsky.social but what about increased linezolid doses???
#DDIs, #obesity ???
Some case studies in patients with respiratory infections/ ARDS suggest different oxidative pathways and up regulation of CYP expression that may influence #linezolid concentrations #antimicrobials2025
@cindyclau.bsky.social
#linezolid does one dose fit all????
Most likely not! Dr Cindy Lau goes through some scenarios - elderly, renal and hepatic impairment, #DDIs - where dose reductions may be warranted to improve patient care (& reduce toxicities)
#antimicrobials2025 #IDsky #amssky
Kicking off the #pharmacysymposium
We have @michyong.bsky.social highlighting the use of marabivir in tricky #ID populations #CMV and real world use beyond the clinical trials. (With promising clinical effectiveness) #antiviralstewardship
#antimicrobials2025
Highlighting undocumented off-label topical use of rifampicin during surgery in Australian hospitals, and opportunities for AMS #Antimicrobials2025 #ASA2025 #rifampicin #surgery #AntimicrobialStewardship @edraby.bsky.social #MattRawlins
Urinary concentrations of antibiotics much more variable bt patients (compared to variability in blood conc). Many variables to consider including fluid intake, variability across a day, other urodynamic factors - Iain Abbott discussing complexity of treating MDR UTIs #Antimicrobials2025 #AMR #UTI
@iainabbott.bsky.social
#antimicrobials2025
Excellent summary slides of current and future oral antimicrobials for #UTIs and what’s lefts in the case of #MDR UTIs
#IDSky #AMSsky
@iainabbott.bsky.social developing bladder in vitro models, three key factors and comparability to animal models. Fun fact: mice don’t naturally acquire UTIs 🐭 🦠
#antimicrobials2025 #UTIs #gramnegativeinfections #idsky #amssky
@iainabbott.bsky.social developing bladder in vitro models, three key factors and comparability to animal models. Fun fact: mice don’t naturally acquire UTIs 🐭 🦠
#antimicrobials2025 #UTIs #gramnegativeinfections #idsky #amssky
Should we still be thinking of classifying UTIs using a dichotomous definition - complicated vs uncomplicated?
Dr Iain Abbott explaining that UTIs are described across more of a spectrum …
#Antimicrobials2025 #UTI
@iainabbott.bsky.social
Defining uncomplicated and complicated #UTIs ….
Well it’s complicated! 😅
#antimicrobials2025
#gramnegativeinfections
Fabulous summary slide from Prof Christian Giskes’ presentation on #gramnegative resistance challenges in laboratory susceptibility testing
#antimicrobials2025 #asa2025 #idsky #amssky
More discussions to come in this afternoons #AUSCAST session
#Historical #breakpoints are simply that…
set in a simpler time where lots of knowledge that we now have, was lacking.
#EUCAST has provided guidance on what to do when breakpoints are lacking !
Prof Christian Giske
#antimicrobials2025 #IDsky #AMSsky
#antimicrobials2025
#gramnegative infections
Clinical consequences of ratio vs fixed concentrations with Prof Christian Giske
Multiple challenges associated with AMR testing of Gm-negative bacteria - may result in over-reporting of resistance rates (e.g cefiderocol) potentially denying patients optimal treatment options, or under-reporting with life-threatening consequences - Prof Christian Giske #Antimicrobials2025 #AMR
Fluoroquinolone resistance in E.coli still lower in Australia compared to most European countries - Jan Bell presenting AGAR data #antimicrobials2025 #ASA2025 #AMR #Ecoli
Surveillance of Gm negative resistance rates in Australia includes all organisms on the WHO list of priority pathogens, & good representation from across Australian states/territories - Jan Bell presenting at #Antimicrobials2025 #ASA2025 #GmNeg
