Link HealthCare Breakfast Symposium - Diving into Difficult-to-Treat Gram-Negative Infections in Australia; addressing one of the most pressing challenges in antimicrobial resistance.
#AMR #InfectiousDiseases #GramNegative #GNB #AMS #antimicrobials2026 #ASA #idksy #Medsky

#UrinaryTractInfection34 #UTI #Pyelonephritis #Cystitis #Urethritis #Ecoli #ProteusMirabilis #KlebsiellaPneumoniae #StaphylococcusSaprophyticus #Enterococcus #PseudomonasAeruginosa #GramPositive #GramNegative #InfectiousDiseases #Microbiology #Hematology #Pathology #MedicalInfographic #ClinicalMedicine #UTISymptoms #UTITreatment #UrineDipstick #LeukocyteEsterase #Nitrates #Antibiotics #TMP_SMX #BroadSpectrumAntibiotics #AcutePyelonephritis #ChronicPyelonephritis #MedStudentNotes #iprakashmishra

#UrinaryTractInfection34
#UTI #Pyelonephritis #Cystitis #Urethritis #Ecoli #ProteusMirabilis #KlebsiellaPneumoniae #StaphylococcusSaprophyticus #Enterococcus #PseudomonasAeruginosa #GramPositive #GramNegative #InfectiousDiseases #Microbiology #Hematology #Pathology #MedicalInfographic

U01.03.018 Bacterial endotoxin Bacterial endotoxins are lipopolysaccharide (LPS) molecules found in the outer membrane of Gram-negative bacteria. The lipid A component is toxic and responsible for activating macrophages and the complement system, leading to fever, hypotension, disseminated intravascular coagulation (DIC), and septic shock.

Bacterial endotoxins from Gram-negative bacteria cause fever, inflammation, and septic shock via lipid A activation. #BacterialEndotoxin #LPS #GramNegative #Sepsis #SepticShock #LipidA #Microbiology #Immunology #Pathophysiology #USMLE #MedicalEducation

U01.03.016 Features of exotoxins and endotoxins Match each bacterial exotoxin to its causative organism and mechanism of pathogenesis. Focus on how these toxins act at the cellular level — whether they block neurotransmission, inhibit protein synthesis, or alter intracellular signaling (like cAMP). Understanding these mechanisms is essential for mastering microbiology concepts in USMLE Step 1 and clinical reasoning.

Learn key differences between bacterial exotoxins and endotoxins and their clinical effects. #Exotoxins #Endotoxins #BacterialToxins #Microbiology #Pathogenesis #GramNegative #GramPositive #LPS #ToxinMechanism #USMLE #MedicalEducation #ClinicalMicrobiology #SepticShock #BacterialVirulence

Microscopy Reveals Polymyxin Antibiotics Kill Gram‑Negative Bacteria

Atomic force microscopy captured the first real‑time images of polymyxin antibiotics breaching E. coli’s outer membrane, showing bumps that cause membrane rupture. Read more: getnews.me/microscopy-reveals-polym... #polymyxin #gramnegative

How Polymyxin Antibiotics Break Down Bacterial Armor

Polymyxin B forces active E. coli to shed its outer membrane within minutes, creating holes that let the drug in, as seen in atomic‑force microscopy images. getnews.me/how-polymyxin-antibiotic... #polymyxin #antibiotics #gramnegative

Cryo‑EM Uncovers Bacterial Membrane Complexes for New Antibiotics

Cryo‑EM revealed the structures of two E. coli membrane complexes—OmpC₃‑MlaA‑MlaC and TolQ₅R₂A motor‑stator—key to lipid balance, reported in JACS and Nature Communications. getnews.me/cryo-em-uncovers-bacteri... #cryoem #gramnegative #antibiotics

#TechnologyTuesday
𝗧𝗵𝗶𝗼𝘂𝗿𝗲𝗮 𝗔𝗻𝘁𝗶𝗯𝗶𝗼𝘁𝗶𝗰𝘀 𝗳𝗼𝗿 𝗔𝗰𝗶𝗻𝗲𝘁𝗼𝗯𝗮𝗰𝘁𝗲𝗿 𝗯𝗮𝘂𝗺𝗮𝗻𝗻𝗶𝗶

🔬 @helmholtzhzi.bsky.social

🔎 Learn more about this #technology on our website: www.ascenion.de/technologiea...

#Antibiotics #AMR #Acinetobacter #GramNegative #InfectiousDiseases #SmallMolecule #ESKAPE

Global action urgently needed to tackle antimicrobial resistance, experts warn Researchers from King's College London have called for urgent changes to the way new antibiotics are developed to address the growing problem of antimicrobial resistance (AMR).

Global action urgently needed to tackle #antimicrobial resistance ...

| #bacteria | #AMR | #antimicrobialresistance | #antibiotics | #GramNegative | #Klebsiella | #Acinetobacter | #pneumonia | By @kingscollegelondon.bsky.social‬ via @sciencex.bsky.social‬

🦠 How do #GramNegative bacteria generate D- #AminoAcids for #peptidoglycan? Miyamoto et al. characterized the two multifunctional amino acid transferases TM1255 and TM1698 of Thermotoga maritima with their racemase activity.

➡️ doi.org/10.1002/1873-3468.70034

#bacteria #enzymes #microbiology

Fabulous summary slide from Prof Christian Giskes’ presentation on #gramnegative resistance challenges in laboratory susceptibility testing
#antimicrobials2025 #asa2025 #idsky #amssky

More discussions to come in this afternoons #AUSCAST session

#antimicrobials2025
#gramnegative infections
Clinical consequences of ratio vs fixed concentrations with Prof Christian Giske

Great line up of speakers on Gram negative bacteria #Antimicrobials2025 #ASA2025 #GramNeg #GmNeg #GramNegative