One bold idea grew into a global movement🌎

Tomorrow, we celebrate✨

Your brain on drugs: different psychedelics work in surprisingly similar ways Hundreds of scans hint at how substances such as psilocybin, LSD and ayahuasca alter connections between key areas of the brain.

Hundreds of scans hint at how substances such as psilocybin, LSD and ayahuasca alter connections between key areas of the brain

go.nature.com/3QamxwN

Using time series graphs to make causal claims be like

One thing I will always give MDPI is that they don't hide what they are. They're fee-for-service publishers and that's it. I don't like, but it's more honest than the "real" publishing houses, who exploit scientists and turn outrageous profits, all while positioning themselves as "the good ones."

Whoa. You can do that?!

Psychedelic Medicine | Ahead of Print Psychedelic Medicine

At long last, religious leaders study published, in Psychedelic Medicine | Ahead of Print www.liebertpub.com/toc/psymed/0/0

After Controversy, the Psilocybin & Religious Leaders Study Is Finally Published

Johns Hopkins and NYU have released their research on the effects of psilocybin on religious leaders via a journal article in Psychedelic Medicine.

The study: www.liebertpub.com/doi/10.1089/...

🧠 🍄 ⚡️🐭

Now published in @natneuro.nature.com

Psilocybin enhances fear extinction by reshaping retrosplenial cortex ensembles—suppressing fear neurons, recruiting extinction neurons + boosting plasticity to enable behavioral flexibility

nature.com/articles/s4159…

The Interdisciplinary Annotated Psychedelic Research Bibliography of 2024 - Psychedelic Alpha Psychedelic Alpha’s Medical Advisor, Michael Haichin, compiled a list of over 500 notable psychedelics-related publications from 2024. He then presented it to a group of researchers from varying…

📚✨ ~500 Papers. ~30 Researchers & Experts. One Annotated Psychedelics Bibliography...

Very excited to share the 2024 edition of Psychedelic Alpha's Interdisciplinary Annotated Psychedelic Research Bibliography, by @michaelhaichin.bsky.social.

psychedelicalpha.com/news/the-int...

Major praise to the @nyulangone.bsky.social podcast team.

I expected just a little internal thing, but they did an AMAZING job digging into the science and creating a great show.

Check it out -
YouTube (full-length): youtu.be/h8Thc-BDvZ0A...
Spotify: open.spotify.com/episode/3WHK...

Our new paper - the first peer-reviewed brain and phenomenological examination of 5-MeO-DMT is out in Neuro of Consciousness.

TLDR: We tested whether ‘the mount Everest’ of psychedelics could induce a complete state of consciousness deconstruction while preserving awareness. 1/n

#neuroskyence

Network control energy reductions under DMT relate to serotonin receptors, signal diversity, and subjective experience - Communications Biology Continuous EEG-fMRI before during and after administration of the psychedelic DMT reveals time-resolved alterations in human brain dynamics.

Continuous EEG-fMRI before during and after administration of the psychedelic DMT reveals time-resolved alterations in human brain dynamics.

@parkersingleton.bsky.social

doi.org/10.1038/s420...

For those attending #SOBP2025 in Toronto next week:
don't miss out on this year's awesome Fireside Chats! 🧠🎉🍁

#neuroskyence #psychology #ClinicalPsych #psychiatry
#psychiatryresearch

@samkrimmelneuro.bsky.social shows the utility of Precision Functional Mapping deep into the brainstem! The red nucleus turns out to be much more potentially interesting for cognitive neuroscience than anyone thought, including connectivity to the Somato-Cognitive Action Network.

The Coming Out of a Transgender Scientist "I know that I am making the right decision because whenever I think about changing my gender role, I am flooded with feelings of relief."

We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.

It's not a bad idea to go to the local Walmart or big box retailer and buy lots of consumables now. From toothpaste to soap, anything you can find storage space for, buy before they have to replenish inventory.

Even if it's made in the USA , they will jack up the price and blame it on tariffs.

Psilocybin’s lasting action requires pyramidal cell types and 5-HT2A receptors - Nature A pyramidal cell type and the 5-HT2A receptor in the medial frontal cortex have essential roles in psilocybin’s long-term drug action.

Our latest study identifies a specific cell type and receptor essential for psilocybin’s long-lasting neural and behavioral effects 🍄🔬🧠🧪

Led by Ling-Xiao Shao and @ItsClaraLiao

Funded by @NIH @NIMHgov

📄 Read in @nature.com - www.nature.com/articles/s41...

1/12

AOC and Bernie in front of the rally crowd in Denver

Zoomed out crowd shot of 34,000 people in downtown Denver with Colorado mountains in the background

Tonight an unbelievable **34,000 people** gathered for our Denver rally to take on billionaires and win our country back.

This was the largest political gathering in Denver since Obama in 2008.

Also bigger than the 2024 DNC.

And the largest ever rally in Bernie’s career (and obviously, mine too).

‘Scientists will not be silenced’: thousands protest Trump research cuts Researchers at Stand Up for Science rallies voice defiance against the policies of US President Donald Trump’s administration.

Standing with all my fellow scientists in solidarity 🧪 www.nature.com/articles/d41...

One of the NIMH PIs whose name is the termination list: Sooyhun Lee, whose lab just published this beautiful @nature.com paper (that has received too little press because comms at NIH are down). Read! Cite!

www.nature.com/articles/s41...

Yes

I'm not sure that our study necessarily implies that one should not average trials - averaging will always have its place. However, our results do show that there is substantial and meaningful variability across trials that is lost when averaging. #neuroscience #neuroskyence

RFK Jr. confirmed as Trump’s health secretary; Federal lawsuit against Oregon’s psilocybin program; Changing psilocybin laws in India? Plus: Dr. Bronner’s sued for wrongful death, and Rhode Island considers decriminalization bill

RFK Jr. confirmed as Trump’s health secretary; Federal lawsuit against Oregon’s psilocybin program; Changing psilocybin laws in India? themicrodose.substack.com/p/rfk-jr-con...

move slow and fix things

A flurry of new state bills; Preliminary synthetic 5-MeO-DMT phase II results; Lessons from a suicide Plus: Evaluating Oregon’s psilocybin services workforce

This week's news in psychedelics: A flurry of new state bills; Preliminary synthetic 5-MeO-DMT phase II results; Lessons from a suicide themicrodose.substack.com/p/a-flurry-o...

Global meta-analysis shows action is needed to halt genetic diversity loss - Nature A comprehensive meta-analysis of global terrestrial and marine genetic diversity covering more than three decades of research demonstrates rapid loss of genetic diversity and identifies conservation i...

How can we stop genetic diversity loss? A meta-analysis in @nature.com finds the conservation strategies designed to improve environmental conditions, increase growth rates, and introduce new individuals can maintain or increase genetic diversity🧪https://www.nature.com/articles/s41586-024-08458-x

a sign that says " what is even happening " next to a dumpster ALT: a sign that says " what is even happening " next to a dumpster

How it feels to be working on a grant application right now.

Photo of Bishop Mariann Edgar Budde.

This is the face of courage and compassion. Thank you Bishop Mariann Edgar Budde for speaking truth to power on behalf of the marginalized.

Psychedelic mental health research is booming—but how do we keep up with rapidly evolving evidence? 🌱 Our team proposes a living evidence synthesis approach to ensure clinicians, policymakers, and the public have access to the latest, most reliable data.
🔗 www.nature.com/articles/s44...
🧪🧵