Advancing what’s possible in #PFAS analysis takes new ways of thinking.
Scientists at Eurofins are using the combined power of MOBILion's MOBIE® with Agilent Technologies’ QTOF to enable both deep characterization and high-throughput workflows.
Partnerships like this redefine what’s possible.
Most MS/MS workflows discard signal for specificity.
Quadrupoles can eliminate ~99% of ions at the source due to architectural limits.95–99% duty cycle ≠ efficiency if only 1–10% of ions reach the detector.
The next leap won’t come from accelerating waste, but eliminating it.
#Proteomics
What if PFAS signals we report as single compounds are actually multiple structures?
Environmental samples aren’t clean, interference + similar compounds complicate analysis.
At Eurofins, Sarah Choyke, PhD uses high-res mobility to add separation and uncover hidden patterns.
#Trailblazers2026
A lot is happening at ASMS… you won’t want to miss it.
Behind velvet ropes, our hospitality suite unlocks concepts we’ve never shown in person.
🤫 Find the password
🤫 Make your voice heard
🤫 Win prizes
Booth, posters, and seminars will be in full swing.
If you’re at ASMS, you’ll want to find us.
A growing number of companies, like Nestle' are going beyond what’s required in #PFAS analysis, and it’s becoming clear why.
HRIM enables:
• Separation of linear and branched isomers
• Full PFAS profile in <10 min
• No added chromatographic burden
www.mobilionsystems.com/resources?ca...
Working at the intersection of research & biopharma, the goal isn’t more data, it’s more understanding.
In Jared Auclair’s lab, adding high-resolution ion mobility brings structural insight. Helping explain how molecules behave, not just what they are.
#Trailblazers2026
Katie Spruance is our April MOBILion Champion 🎉
Katie shapes what it feels like to work at MOBILion. As our HR leader, she supports hiring, growth, and our team every day with a people-first mindset.
She also created this award, making it even more special to recognize her.👏
Everyone’s moving toward TOF—even if they won’t call it that 😉 Why? Speed.
Higher MS2 acquisition rates = more precursors sampled before they elute → deeper proteome coverage.
With SLIM + HRIM, we push >1000 Hz while maintaining efficiency.
And we’re just getting started.
#Trailblazers2026
Logan Pierpoint, Senior Service Engineer at MOBILion, works where there’s no playbook.
Every lab is different. Every challenge is new.
Working alongside Agilent Technologies, he’s solving problems in real time to make sure our customers are supported.
#Trailblazers2026
For a scientist, a first conference talk isn’t just a talk, it’s a milestone.
At Pittcon 2026, Lauren Royer Dissinger delivered her first presentation, showcasing PAMAF™+ HRIM for deeper proteome coverage and high-throughput workflows.
We’re proud so proud of Lauren!
#Trailblazers2026 #Proteomics
High-throughput bioanalysis has always meant tradeoffs. This work shows you don’t have to choose.
By combining rapid LC with HRIM, researchers achieved fast separations, resolved compounds, and robust quantification, all in minutes per sample.
Read more: sciencedirect.com/science/arti...
We generated a mirror plot after HRIM removed interference. A scientist thought we plotted the pure standard twice.
That’s the shift.
Cleaner spectra. Less manual review. Stronger AI/ML.
When data quality improves, everything downstream follows.
#Trailblazers2026
At MOBILion Systems, Inc., our people are at the core of everything we do.
Behind every milestone is a team solving problems, supporting one another, and driving progress. Each person brings unique value that strengthens our work.
Grateful for a team that pushes boundaries.
Proteomics has made huge progress, thousands of proteins in a single run is now routine.
But we’re still only sampling the proteome. Limited coverage, missed modifications, and lost signal mean much of biology remains invisible.
The next leap is rethinking how we measure.
#Trailblazers2026
Insight is still a challenge in proteomics.
Uncertainty across workflows and same-mass molecules limit interpretation.
As Olga Vitek notes: we need reproducible, scalable data for predictive biology.
HRIM enables high-resolution separation for clearer, consistent datasets.
#Trailblazers2026
Miriam Fico is our March MOBILion Champion 🎉
Always ready to step in, solve problems, and support the team, Miriam connects R&D, Product, and Applications while continuously improving how we work.
Congrats, Miriam! 👏
#Trailblazers2026
Abandoning the Quadrupole with PAMAF™
That’s not the full story.
SLIM + PAMAF shifts LC-MS performance from duty cycle to ion utilization, enabling 100× signal gains and >1000 Hz speeds on a QTOF.
Read more:
www.genomeweb.com/proteomics-p...
#Proteomics #PAMAF
Sometimes what looks like one peak… isn’t.
Co-eluting compounds make it hard to tell what you’re seeing, impacting confidence.
At Los Alamos, Austin Anderson’s team is evaluating MOBIE® to add a second separation dimension and resolve LC overlaps.
#Trailblazers2026
Separating closely related lipid molecules remains a major analytical challenge. At the Gordon Research Seminar & Conference on Lipidomics, Amie Solosky will present work using high-resolution ion mobility to distinguish oxylipin isomers.
GRS: Mar 15, 9:20 AM PST | GRC: Mar 18
What happens when you add a gas-phase separation between LC and MS?
In Episode 50 of Concentrating on Chromatography, MOBILion CTO Daniel DeBord discusses HRIM, SLIM, and how ion mobility is expanding analytical workflows.
Watch: www.youtube.com/watch?v=fDJX...
Clinical research demands faster results without sacrificing data quality. Tim Garrett’s lab uses ion mobility to add an extra separation dimension, enabling faster analysis while maintaining the sensitivity needed for complex biological samples.
#Trailblazers2026 #IonMobility
Happy International Women's Day!
At MOBILion Systems, we’re grateful for the incredible women across our organization who bring leadership, talent, and dedication to everything they do. They truly bring the heart to our company.
#InternationalWomensDay
The MOBILion team stepped out of the lab and into the kitchen, volunteering at Ronald McDonald House to prepare meals for families whose children are receiving medical care. Grateful to support an organization that provides comfort and community when families need it most.
Two-dimensional separations solve problems 1D methods can’t. A new study from Oliver Schmitz’s lab adds multidimensionality at the ion source with rapidly switchable ESI + plasma ionization, paired with HRIM from MOBILion on an Agilent QTOF.
Read: pubs.acs.org/doi/pdf/10.1...
Behind every high-resolution measurement is the need to turn complex data into meaningful insight. As an Informatics Scientist at MOBILion, Lauren Royer Dissinger ensures ion mobility data is reproducible, high-quality, and actionable for researchers. #Trailblazers2026
Heading to #Pittcon2026? Join MOBILion’s Lauren Royer for an oral presentation on how PAMAF™ + HRIM enables precursor–fragment alignment without quadrupole isolation, improving fragment coverage and delivering >3× protein IDs.
📍Room 304C | Mar 11 | 9:40 AM
Lysine succinylation regulates metabolism but remains difficult to quantify proteome-wide. Using PAMAF™ on a SLIM-enabled HRMS prototype, Schilling et al. resolved isomeric PTMs and quantified ~1,000 succinylated peptides in tissue samples. www.sciencedirect.com/science/arti...
Some of the hardest challenges in proteomics and metabolomics appear after measurement. As Gary Patti noted, faster workflows often trade certainty for speed. Adding another separation dimension is helping labs gain confidence without added complexity. #Trailblazers2026
Meet our February MOBILion Champion: Michael Slemko 👏
Mike brings systems-level thinking, steady leadership, and cross-functional collaboration to every challenge, creating clarity, driving alignment, and raising the bar for those around him.
Congratulations, Mike!
#Trailblazers2026
Quadrupole isolation wastes ions and creates chimeric MS/MS.
Our new preprint with Biognosys & Benjamin Orsburn introduces PAMAF™: size-based isolation in mobility space with near-100% ion use and >500 Hz MS2.8,000+ proteins in DIA-PAMAF.
www.biorxiv.org/content/10.6...
