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Posts by Heinz Freisling

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Don’t let your students use AI as a ghostwriter How a research proposal generated by artificial intelligence transformed my approach to teaching and supervision.

"Working scientists must reaffirm that the human brain is still much better at innovation than AI is."

www.nature.com/articles/d41...

6 hours ago 0 0 0 0
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Challenges and promises of nutritional epidemiology to investigate cancer etiology Abstract. The relationship between diet and cancer is complex and has been the subject of scientific controversy. Recent estimates of the fraction of cance

👉Challenges and promises of nutritional epidemiology to investigate cancer etiology

academic.oup.com/jncimono/art...

1 day ago 1 0 0 0
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Science must protect thinking time in a world of instant communication E-mails and instant messaging are core to research — but also a distraction. Researchers should study their impact on science, and how they can claw back time to concentrate.

Science must protect thinking time in a world of instant communication www.nature.com/articles/d41...

2 weeks ago 0 0 0 0
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Proteomics signature of moderate-to-vigorous physical activity and risk of multimorbidity of cancer and cardiometabolic diseases - Communications Medicine Stein et al. identify circulating blood proteins linked to regular moderate-to-vigorous physical activity in over 33,000 UK Biobank participants. Many of these proteins are associated with lower risk ...

Your blood remembers when you excercise. 🏃‍♀️🧬
👉220 proteins shifted with physical activity, many tied to lower cancer and cardiometabolic risk.
🧐A glimpse into the biology of prevention.
@michaeljstein.bsky.social
@wcrf.org
@ukbiobank.ac.uk
www.nature.com/articles/s43...

4 weeks ago 2 0 0 0
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Point of no returns: researchers are crossing a threshold in the fight for funding With so little money to go round, the costs of competing for grants can exceed what the grants are worth. When that happens, nobody wins.

Point of no returns: researchers are crossing a threshold in the fight for funding www.nature.com/articles/d41...

1 month ago 0 0 0 0
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Don’t deprioritize curiosity-driven research Around the world, governments are demanding that research funding follow broader political priorities. They should be careful what they wish for.

Don’t deprioritize curiosity-driven research www.nature.com/articles/d41...

1 month ago 0 0 0 0
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Open-source AI tool beats giant LLMs in literature reviews — and gets citations right Researchers can deploy the cheap and transparent model on their own computer system.

Open-source AI tool beats giant LLMs in literature reviews — and gets citations right www.nature.com/articles/d41...

2 months ago 0 0 0 0
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I’m going to halve my publication output. You should consider slow science, too If we don’t slow down, the research enterprise is going to crash, argues Adrian Barnett.

This 👉
I’m going to halve my publication output. You should consider slow science, too www.nature.com/articles/d41...

3 months ago 1 0 0 0
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The rich stopped buying yachts the year time went on sale Second thoughts.

The rich stopped buying yachts the year time went on sale www.nature.com/articles/d41...

3 months ago 0 0 0 0
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Interested in cancer prevention through #pyhsical activity?
👉

3 months ago 0 0 0 0
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The academic community failed Wikipedia for 25 years — now it might fail us Artificial-intelligence systems are feeding on Wikipedia without giving back, and academic indifference is threatening the survival of what is arguably the most widely used reference work on the plane...

The academic community failed Wikipedia for 25 years — now it might fail us www.nature.com/articles/d41...

3 months ago 0 0 0 0
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Does lifestyle explain the relationship between socioeconomic position and multimorbidity of cancer and cardiometabolic diseases? A mediation analysis applied to the European Prospective Investigation... Background Multimorbidity is socially patterned, with lower socioeconomic position (SEP) linked to higher risk. We examined whether a Healthy Lifestyle Index (HLI) mediates the SEP–multimorbidity asso...

👋Lower socioeconomic position = higher #multimorbidity of #cancer #diabetes & #CVDs.
👉Healthy lifestyle partly mediates this link, more so in men (29%) than women (11%).
jech.bmj.com/content/80/1/3

4 months ago 0 0 0 0
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A ten-year drive to credit authors for their work — and why there’s still more to do Information about the roles of each author of a paper can help to build trust, integrity and responsible research assessment. Coordinated efforts are needed to consolidate progress.

A ten-year drive to credit authors for their work — and why there’s still more to do www.nature.com/articles/d41...

4 months ago 0 0 0 0
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Clinical Obesity and All-Cause and Cause-Specific Mortality in UK Biobank This research evaluates the association between a new definition of obesity with mortality data in the UK Biobank.

jamanetwork.com/journals/jam...

5 months ago 0 0 0 0
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👉 With Lancet's refined definition of #obesity, we found clinical obesity (excess fat + organ dysfunction) linked to a 56% higher #mortality vs. no obesity.
👉 #BMI alone misses key risks.
@michaeljstein.bsky.social
@uniregensburg.bsky.social
🙏 @wcrf.org
👉 10.1001/jamainternmed.2025.4978

5 months ago 3 1 1 0
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Regression adjustment for causal inference Causal inference identifies and quantifies the effect of an exposure (the hypothetical cause) to an outcome. While randomised controlled trial design is the preferred method for establishing and measu...

Regression adjustment for causal inference bmjmedicine.bmj.com/content/4/1/...

5 months ago 2 0 0 0
Client Challenge

👋Imaging-derived organ measurements outperform #BMI in predicting risks for #diabetes, #cancer & #mortality.

👉Advanced imaging may redefine how we assess obesity-related health risks. #ObesityResearch

doi.org/10.1186/s129...

6 months ago 0 0 0 0
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Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis AbstractIntroduction. There is convincing evidence that overall adiposity increases the risks of several cancers. Whether the distribution of adiposity pla

👋MR analyses (~40K Europeans) showed causal links between specific fat depots and #cancer
👉Liver fat ↑ liver cancer risk
👉Pancreas fat ↑ ovarian cancer risk
👉Abdominal subcutaneous adipose tissue ↑ endometrial ↑ liver, ↑ esophageal, ↑ovarian cancer
@wcrf.org
👉 doi.org/10.1093/jnci...

6 months ago 1 1 0 0
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Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis A healthy plant-based diet might reduce the burden of multimorbidity of cancer and cardiometabolic diseases among middle-aged and older adults.

👋Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis - The Lancet Healthy Longevity
#cancer #cvd #diabetes
www.thelancet.com/journals/lan...

8 months ago 0 0 0 0
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Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis Although 10 000 steps per day can still be a viable target for those who are more active, 7000 steps per day is associated with clinically meaningful improvements in health outcomes and might be a mor...

Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis - The Lancet Public Health www.thelancet.com/journals/lan...

8 months ago 0 0 0 0
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📢Postmenopausal women with CVD have a 31% higher risk of breast cancer with each 5 kg/m² increase in BMI, compared to a 13% increase in those without CVD. #BreastCancer #CVD

🙏 @wcrf.org

👉 doi.org/10.1002/cncr...

9 months ago 1 0 0 0
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Proteomics signature of physical activity and risk of multimorbidity of cancer and cardiometabolic diseases Background: Cancer, cardiovascular diseases (CVD), and type 2 diabetes (T2D) may co-occur, a condition referred to as multimorbidity. Physical activity is inversely associated with each of these disea...

👋 Preprint for comments:
@michaeljstein.bsky.social et al.
#proteomics #physicalActivity #multimorbidity #cancer
www.medrxiv.org/content/10.1...

1 year ago 1 0 0 0
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Associations between cardiometabolic comorbidities and mortality in adults with cancer: multinational cohort study Objective To examine separate and joint associations between pre-existing cardiometabolic comorbidities and all cause and cause specific mortality in adults with cancer.Design Multinational cohort stu...

👋Adults with #cancer with a history of #diabetes and/or #cardiovascular diseases have a survival disadvantage compared with those with no history of these comorbidities.

🙏Institut national du cancer (INCa)

bmjmedicine.bmj.com/content/4/1/...

1 year ago 1 0 0 0

@foodwatch-int.bsky.social 👉

1 year ago 0 0 0 0
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Food environment and obesity: a systematic review and meta-analysis Background Obesity is influenced by a complex, multifaceted system of determinants, including the food environment. Governments need evidence to act on improving the food environment. The aim of this ...

Food environment and obesity: a systematic review and meta-analysis nutrition.bmj.com/content/7/1/...

1 year ago 0 0 0 0
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Alcohol and smoking habits in association with hepatocellular carcinoma risk Smoking and alcohol consumption are modifiable lifestyle risk factors for hepatocellular carcinoma. While they differentially contribute to DNA damage, proto-oncogene activation, and mitochondrial im....

📢#Alcohol and #smoking habits in association with #hepatocellularcarcinoma risk 👉
onlinelibrary.wiley.com/doi/10.1002/...

1 year ago 2 0 0 0
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Dried Fruits, Nuts, and Cancer Risk and Survival: A Review of the Evidence and Future Research Directions Dried fruits and nuts contain high amounts of nutrients and phytochemicals—all of which may have anticarcinogenic, anti-inflammatory, and antioxidant properties. This narrative review summarizes the e...

👋reminder
⬆️a higher consumption of #nuts is inversely associated with risk of certain #cancers and dying from cancer.
www.mdpi.com/2198962

1 year ago 0 0 0 0
Evaluating agreement between individual nutrition randomised controlled trials and cohort studies - a meta-epidemiological study | BMC Medicine

👋An overdue formal head to head of #RCTs and #cohort studies in #nutrition 👉
👏 Stadelmaier et al.

rdcu.be/d8Zgj

1 year ago 0 0 0 0
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How one language family took over the world: ancient DNA traces its spread Millennia-old genomes suggest Indo–European tongues originated from the Caucasus mountain region.

How one language family took over the world: ancient DNA traces its spread www.nature.com/articles/d41...

1 year ago 0 0 0 0
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How are researchers using AI? Survey reveals pros and cons for science Despite strong interest in using artificial intelligence to make research faster, easier and more accessible, researchers say they need more support to navigate its possibilities.

www.nature.com/articles/d41...

1 year ago 1 1 0 0