Beautiful cover this time - makes me miss the days when they were still produced to adorn real print issues in all their glory!

Devastating to learn of Greg Hannon's passing, who made several seminal discoveries in the field of RNA. What a loss.
www.cruk.cam.ac.uk/news/in-memo...

New paper from the lab out in Cell Death & Disease
@cddpress.bsky.social @cbm-csic-uam.bsky.social
"Transcription-dependent and -independent functions of Drosophila p53 isoforms in the induction of apoptosis and senescence-associated tumorigenesis.” #p53 #Drosophila Thread 1/9👇👇👇

El biólogo Ginés Morata, Medalla Echegaray de la RAC 2025 - Centro de Biología Molecular Severo Ochoa Este galardón, el más antiguo en el ámbito científico en España, fue creado en 1905 por iniciativa de Santiago Ramón y Cajal tras la concesión del Premio Nobel a José […]

¡Enhorabuena a nuestro investigador Ginés Morata! La Real Academia de Ciencias de España le concede la Medalla Echegaray por sus investigaciones sobre la regulación genética que da lugar a la diversidad de formas en los organismos. www.cbm.uam.es/index.php/20...

2022 Tweet from Caroline Keroack: "I have a whole PhD I whisper to myself, as I write C1V1 = C2V2 on a paper towel for the 8000th time."

This tweet is all of us.

No estás solo.

Dear all, please see link below for Milano et al, describing a role for BRCA2 (& BRCA1) in the maturation of nascent DNA strand gaps during DNA replication in the presence of PARP inhibitor. Congratulations Larissa and all !

authors.elsevier.com/a/1mtQe3vVUP...

Perspective helps a little.

Just a quick reminder that the first of these Associate Professorships have a closing date for applications of April the 8th. Get your application in now!
Please repost

Del bacteriófago φ29 al cáncer. De la ciencia básica a la biomedicina. Eso es lo que celebró ayer Juan Méndez #AlumniCB @cniostopcancer.bsky.social en su Lección Conmemorativa Margarita Salas: el valor de la ciencia fundamental, reflejado en el espíritu y lema del CBM #DecodingLife

We propose a semi-distributive model for priming in the lagging strand that sets the RSR in a DNA replication control mode (DRC). The DRC modulates the progression of DNA replication through S phase to ensure the maintenance of genomic stability.
@rodrimartinr.bsky.social @cbm-csic-uam.bsky.social

An updated view on lagging strand DNA replication: implications for the replication stress response The process of DNA replication is inherently asymmetric. While the leading strand is synthesized continuously, the lagging strand is copied in small fragments, the Okazaki fragments, requiring the ...

Fresh from the oven! Our new perspectives article where we discuss the interplay between lagging strand DNA replication and the replication stress response.
An updated view on lagging strand DNA replication: implications for the replication stress response www.tandfonline.com/doi/full/10....

“I think it’s a real mistake to forget where the pipeline for all this begins.”

John Diffley reflects on the importance of basic research, his mission to decode DNA replication and recreate it in the lab, and the scientific optimism of the 1960s that helped shape it.
www.crick.ac.uk/news/2026-03...

🦠Las mitocondrias producen la energía de las células

🔎Su mal funcionamiento altera la #microbiota, según un estudio de @cbm-csic-uam.bsky.social 

🔬Restaurar una molécula producida por bacterias intestinales prolonga la vida de ratones con enfermedades mitocondriales

➡️ http://tiny.cc/laq0101

⏰ Deadline approaching!
Apply now for the Chromatin Biology Summer School 2024 and join an inspiring week of science, learning, and community.
Submit before March 29th to be considered for this exciting opportunity: bit.ly/4oGDR8f
#chromatin #summerschool

Almas gemelas

Still one of my all time favorites

Yo voy a empezar a usar Brigadier, a ver qué pasa.

A modular genetic code expansion approach to site-specific lysine acylations A modular strategy combining genetic code expansion with a selective amide bond-forming reaction enables the site-specific installation of lysine acylations on folded proteins. Acylboronates react sel...

🚨 Our new paper is out! 🙌

Bioorthogonal reactions often create bulky, non-native linkages-great for labeling, but not ideal for installing natural PTMs.
We combine GCE with a chemoselective amide-bond forming reaction to install site-specific acylation PTMs.
www.cell.com/chem/fulltex...
1/4

The accessory adapters FAF1, FAF2, and UBXN7 accelerate proteasomal degradation by increasing prior p97-mediated substrate unfolding A group of accessory adapters positions the p97 adapter Ufd1 to boost substrate unfolding and subsequent proteasomal degradation.

VCP/p97’s accessory adapters (FAF1, FAF2, UBXN7) boost unfolding and subsequent proteasomal degradation. #ubiquitin. Our paper is out now:
Science Advances www.science.org/doi/10.1126/...

Our postdoctoral researcher @joanasgrmrtnz.bsky.social, together with other researchers from @cbm-csic-uam.bsky.social, has participated in the video by @contracancerinv.bsky.social to commemorate **Women’s Day (#8M)** to recognize the strength, dedication and talent of women in science 💜

MSCA Postdoctoral Fellowships 2026 MSCA Postdoctoral Fellowships enhance the creative and innovative potential of researchers holding a PhD and who wish to acquire new skills through advanced training, international, interdisciplinary ...

🚀 Looking for MSCA Postdoctoral Fellowship candidates (2026)!
Join the Malaria Epigenomics Lab (@ipblncsic.bsky.social).
✔ PhD by Sept 2026
✔ ≤8 yrs postdoc
✔ Mobility rule
✔ Infectious diseases/genomics expertise
📩 elena.gomez@csic.es
🔗 marie-sklodowska-curie-actions.ec.europa.eu/calls/msca-p...

The Sfeir Lab at MSKCC is hiring a Research Assistant!
We are looking for a motivated scientist with at least 2 years of research experience and a two-year commitment. Learn more about our work here www.sfeirlab.com, and message me your CV and cover letter if interested

Work with us at CNAG! 👇🏻👏🏻

Como parte de la iniciativa Conexión Cáncer y dentro del catálogo de charlas del CSIC, esta semana he visitado el IES El Burgo en Las Rozas para acercar a los alumnos de secundaria a la biología del cáncer y nuestro trabajo en el @cbm-csic-uam.bsky.social . Gracias por la gran acogida.

We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab.
@mrclmb.bsky.social

Please get in touch if you have any questions.
www.nature.com/naturecareer...

¡No te pierdas la IV Conferencia Severo Ochoa! 🌱 Del 18 y 19 de junio de 2026 en el Jardín Botánico de Valencia, organizado por #FCYSO junto a #SEBBM
ℹ️https://f.mtr.cool/ozifygzkrh

Bay leaf is a must for the basic rice recipe for me.

We;re hiring Junior Group Leaders! 🔬✨
We’re looking for researchers in immunology, chemical biology, AI in biology, or protein design to launch their own independent groups in our collaborative, international environment.

www.nki.nl/news-events/...