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Head-to-head comparison of BaEV- vs HERV-W–pseudotyped lentiviral vectors shows BaEV-LVs consistently outperform HERV-W-LVs in T, B, NK cells and CD34+ HSPCs, with superior SRC transduction in vivo.
#GeneTherapy #LentiviralVectors #HSPC #CellTherapy #GeneEditing #Immunotherapy

2 months ago 1 0 0 0
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Baboon endogenous retrovirus (ERV) envelope pseudotyped lentiviral vectors outperform human ERV lentivectors for transduction of T, B, NK and HSPCs
www.nature.com/articles/s41... @genetherapy.bsky.social

2 months ago 8 3 1 1