#prostatecancer #menshealth #NICE #NHS #prostatecancerdrug #highriskprostatecancer #ProstateCancerUK #abiraterone #JnJ #Zytiga #brandedpharmaceuticals #generics #HSPC #NICEcosteffectivenesscalculations #advancedprostatecancer #prostatecancerscreening #PSAtesting #BRCAgenevariants
zurl.co/ZNxJT
Head-to-head comparison of BaEV- vs HERV-W–pseudotyped lentiviral vectors shows BaEV-LVs consistently outperform HERV-W-LVs in T, B, NK cells and CD34+ HSPCs, with superior SRC transduction in vivo.
#GeneTherapy #LentiviralVectors #HSPC #CellTherapy #GeneEditing #Immunotherapy
Lutetium Lu 177 Vipivotide Tetraxetan Shows Activity in Oligometastatic HSPC #oncology #pcsm #HSPC #prostatecancer
www.onclive.com/view/lutetiu...
✅ L’#ADN du #CssDNA atteignait 3 à 5 × une efficacité de détonation supérieure à celle de l’ADN linéaire ss, dans de nombreux cas au-dessus de 40 %
✅ Il permettait des insertions à plusieurs emplacements dans les #HSPC
Efficace, mais sous-optimal, car cela affecte l’engrevent des #HSPC et les événements d’insertion génique de maintenance in vivo.
C’est pourquoi nos équipes ont exploré des alternatives non virales.
www.linkedin.com/posts/cellec...
🧬 #Cellectis : et si une simple forme d’ #ADN pouvait redéfinir la façon dont nous modifions les cellules souches ? 🧬
Pendant des années, la plupart des insertions géniques dans les cellules souches et progénitrices hématopoïétiques ( #HSPC) reposaient sur des vecteurs viraux.
#menshealth #NICE #prostatecancer #hormonesensitiveprostatecancer #HSPC #abiraterone #JnJ #Zytiga #brandedpharmaceuticals #NICEguidance #advancedHSPC #androgendeprivationtherapy #ADT #Bayer #Nubeqa #Astellas #Xtandi #Erleada #genericmedicines #ProstateCancerUK
zurl.co/fzdbT
#menshealth #NICErecommended #Bayer #prostatecancer #Nubeqa #darolutamide #Nubeqaregimen #hormonesensitiveprostatecancer #HSPC #androgendeprivationtherapy #ProstateCancerUK #advancedHSPC #ARANOTEtrial #castrationresistantprostatecancer #CRPC #mHSPC #NationalProstateCancerAudit #NPCA
zurl.co/dDIIm
So far, I've shared research from 2024 @science.org about mature #immune cells. But today, a look back at findings about hematopoietic stem and precursor cells from our pages.
#HSC #HSPC
Amazing, formative work by my friend, collaborator, research role model @nnekauferemd.bsky.social
Beyond the impact she is having on the care of people living with cirrhosis, she inspires me to think more expansively about what serious illness and #hspc palliative care are—and can be—as we grow…🧵
Sounds like the #hspc chat was a little clunky this week here. Maybe @ehahnmd.bsky.social or @ctsinclair.bsky.social can give us advice based on their experience?