BREAKING: The FDA has approved Travere Therapeutics Filspari (sparsentan) to treat adults and children ages 8+ with focal segmental glomerulosclerosis (FSGS), reducing proteinuria. As the first and only FDA-approved treatment for #FSGS, it offers new hope for patients: https://bit.ly/481S6iA

#NephMadness 2026: The Effluent Eight It’s time for our first step on the road to naming a Champion, announcing the winners of each of this year’s regions! Is your The mighty Blue Ribbon Panel has conferred, and the picks a…

The #Effluent8 of #NephMadness are live!

ajkdblog.org/2026/04/02/n...

Dogs 🐶win? That seems like a #BlueRibbonFail 😏

The rest seem solid choices IMO!

#NephMadness party was a huge success!
Awesome presentations by both peds and IM team!
@nephmadness.bsky.social

This year we are hosting a combined Med-Peds Nephrology. Yay!! Finally getting together

#NephMadness party!

Kidney Heroes Of Houston!
We are comically neon!!!

@nephmadness.bsky.social

Something has to change! We need more of us!
#NephSky @nefronica-2rair.bsky.social @aspneph.bsky.social @rheaultm.bsky.social @akcanarikan.bsky.social @jostflynnmd.bsky.social @sugarkro.bsky.social @drm-sudha.bsky.social @and

Taking the reigns — NephJC In April 2014, Swapnil and I launched NephJC—and within weeks we were overwhelmed by the sheer work of running a twice-monthly, Twitter-based journal club. Fortunately, we also had a deep bench of fri...

An announcement

www.nephjc.com/news/2025/11...

#NephJC

@kidneyboy.bsky.social and moi hand over the @nephjc.bsky.social reigns to @nephroseeker.medsky.social & @brianrifkin.bsky.social

These are not FDA approved yet - this trial + VISIONARY for Sibeprenlimab will lead to approval soon

Approved =
Nefecon
Atrasentan
Sparsentan
Iptacopan

(I think)
#Nephjc

Excellent comparison of completed IgAN studies from today's @CSNSCN webinar from Kevin Yau

#NephSky

Late breakers that included children:
✅Setanaxib in Alport (12+)

Late breakers that did NOT include children:
🚫Atacicept in IgAN
🚫CONFIDENCE
🚫PISCES: Fish oil in Dialysis
🚫LIBERATE-D
🚫balcinrenone + dapa
🚫Obintuzumab in lupus nephritis
🚫Sibeprenlimab in IgA
🚫MIL62 in membranous
+more
#KidneyWk

Peds nephrons at #ASN2025 #KidneyWk , participate in @aspneph.bsky.social scavenger hunt and win prizes!
Download ASPNGo App!!

@nefronica-2rair.bsky.social @coleaugust.bsky.social

Clinical importance of prediction tools: 🔬
The prediction tool was developed with the data from 4000 people in multinational and multiracial cohorts and can be generalized to all.
Do you routinely use prediction tools with IgAN patients? #NephJC

Treatment in children: 👶💉
Management is based on RAS blockade, salt restriction, and blood pressure control. Glucocorticoids are used in those with persistent proteinuria or high-risk features, sometimes combined with cyclophosphamide in severe cases.

#NephJC

Off label use tried in small studies, awaiting Double PROTECT study

Noted

NephJC Shorts: MCD and FSGS Outcomes — NephJC A NephJC Shorts discussion of the long term data on kidney failure in FSGS and MCD

🤔 How often is end-stage kidney disease in patients with MCD/ FSGS? #NephSky #MedSky

@brianrifkin.bsky.social dissected the conclusions from the RaDar study in this #NephJCshorts

*the original article from @asnpublications.bsky.social

www.nephjc.com/news/nephjc-...

Everything said and done - although eGFR diff may signal ominous outcomes - practically speaking following one eGFR over time and seeing the eGFR fall predicts outcomes better than anything else ! And that’s what would be feasible across economies ! #NephJC

Introducing NephJC Shorts — NephJC In just over a decade of critical appraisal on NephJC, we have done several experiments. Some of them have worked out phenomenally well, such as the Freely Filtered podcast. Others were not ready for ...

The #NephJC editorial team knows that plenty of papers deserve attention between our bi-monthly, full-length discussions

✨Enter #NephJCShorts - quick hits with a critical eye 🦅 on high-impact reads
www.nephjc.com/news/nephjc-...

#MedSky #NephSky

“The kidney, a tremendously under-celebrated organ, basically does four-dimensional sudoku with ions.”

From Rivka Galchen’s article in @newyorker.com:

“The kidney, a tremendously under-celebrated organ, basically does four-dimensional sudoku with ions.”

And that’s how I’m going to explain it from now on.

Missed the #NephJC yesterday, but increasingly using Ritux for SDNS and even redosing at 6mo-1yr. Some stay in remission longer with add MmF

I do the same with any agent. Treat for 2 years then try off. If relapse, then another 2 years. #NephJc I don’t think there’s great data. Just seems a good balance of risk.

award winner list

Congrats to all the @asnkidney.bsky.social lifetime and mid-career awardees!

@ksusztak.bsky.social @genetickidneydoc.bsky.social @shinamenon.bsky.social @michellejtx.bsky.social and everyone else!

No, as someone who has used it before and now no longer using #NephJC

DDAvP will increase VWF levels but in an uremic mileu does it really help towards platelets adhesion?
#NephJC

Short window to work with!
#NephJC

Would make sense to check VWF otherwise hard to prove anything unless they compare with their previous institutional cohort
# NephJC

T0c
So how does DDAVP skip the bleeding drama? 🩸
🧬 Desmopressin → triggers cAMP → exocytosis of vWF & FVIII from endothelium
➡️ Boosts platelet adhesion in uremic dysfunction
⏱️ Onset: 30–90 min ⏳ Duration: 4–8 h
#NephJC

Due to cost and other logistics we stopped PFA, haven’t used desmo preemptively
#NePhJC

We used to do pre procedure DDAVP for abnormal PFA’s, mostly in CKD/ uremic kids
# NephJC

Peds Nephrologist @texaschildrens.bsky.social
No COI
#NephJC