If you wondered what ‘oidsks’ are - these belong to a species of ‘Haptomonitora typo-didae’. Can frequently be found on the world wide webs.

That's it: #GfE2026 #GfESEBDDSDB2026 is over. Thanks for the science, talks, posters, chairing, discussions, helpers in back & front. See you latest at #GfE2028 for more #DevBio & oidsks for all the fish, plants, mice, worm, flies, frogs, squids, brown algae, human, -oids, whatnots and you.

this must be the source-foto for 50% of „DNA clipart“ available online in which the DNA coils the wrong way 🧬

Part of my history. Martin sparked my interest in developmental biology and made me join the @gfeev.bsky.social The fascinating research presented on meetings like #GfE2026 made me stay.

I though more along the lines: „friends you can choose, family you have“ 🧐 …

Going to a GfE Meeting like #gfe2026 is like meeting friends & family. On the train with fellow COSians (@COSHeidelberg.bsky.social).

Things progress. PhD students graduate, labs change. The door of the glyco lab a.k.a. ‚the sugar cube’ closed as we moved one door further. All that remains is a LEGO memory of it (#Klemmbaustein). Thanks for all the good science, games and fun @encarnischezsal.bsky.social and @kpakari.bsky.social

Thx for reminding @gromesroland.bsky.social freezer was „only“ +39C that Monday, yet it turned everything (🐁🐇🐟) into an undefined goo …. I learned a lot about humans that day: most came holding their noses, laughing and taking fotos of Colin & me in full protection cleaning out the mess. Nice. Not.

@cosheidelberg.bsky.social today

Proud of Kaisa Pakari @kpakari.bsky.social to receive the 2025 Schmeil young researcher award for her #PhD thesis. She established 🐟 models to address disorders of #glycosylation #CDG by advancing #baseediting range for precise genome editing @wittbrodtlab.bsky.social @cos.uni-heidelberg.de

it certainly is!

GfE School 2025

Are you in Germany in September (25th-27th) and ready to present your science? no further hesitation and register for the 15th GfE School on "Lineages: Revealing how Cells make Embryos and Tissues" at Schloss Reisensburg: www.vbio.de/gfe-entwickl... all #devbio enthusiasts and interested welcome!

LAST CHANCE TO REGISTER!

Calling all medaka researchers and enthusiasts!

Don't miss your chance to connect with the growing medaka community, share ideas, and spark new collaborations! The Medaka PI/ERC Indigene Meeting 2025 is just around the corner!

REGISTER NOW → meetmedaka.com

study performed with @kpakari.bsky.social, #medaka and @wittbrodtlab.bsky.social at @cosheidelberg.bsky.social

Establishing an auxin-inducible GFP nanobody-based acute protein knockdown system to mimic hypomorphic mutations during early medaka embryogenesis Creating hypomorphic mutations are crucial to study gene function in vivo, especially when null mutations result in (embryonic) lethality. This is especially the case for enzymes involved in glycosyla...

new #preprint: mRNA delivered degron system w/ GFP-nanobody to efficiently reduce GFP-tagged proteins in an inducible manner in 🐟 Case study: reduction of PMM2 (basis for ER-based #glycosylation) causes hypoglycosylation reported from CDG-patients www.biorxiv.org/content/10.1... #CRISPR #RareDisease

Happy to share our new preprint on lens morphogenesis in ocular organoids. All thanks to Elin Stahl, Miguel Angel Delgado-Toscano, Ishwariya Saravanan, Anastasija Paneva and Jochen Wittbrodt @wittbrodtlab.bsky.social

www.biorxiv.org/content/10.1...

Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model Phenotypic variation arises from the interplay between genetic and environmental factors. However, disentangling these interactions for complex traits remains challenging in observational cohorts such...

New pre-print klaxon: "Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model" led by the excellent Bettina Welz + @saulpierotti.bsky.social from @wittbrodtlab.bsky.social, Felix Loosli, Kiyoshi Naruse and my own lab www.biorxiv.org/content/10.1...

Register quickly and swim by! #medaka #meeting #conference