Fecal microbiota transplantation plus immunotherapy in non-small cell lung cancer and melanoma: the phase 2 FMT-LUMINate trial - Nature Medicine In a phase 2 trial evaluating healthy donor fecal microbial transplantation plus either anti-PD-1 in patients with non-small cell lung cancer or anti-PD-1 and anti-CTLA-4 in patients with melanoma, en...

First evidence that healthy donor fecal microbiota transplant, added to immunotherapy, can enhance efficacy vs cancer
3 clinical trial reports (renal, small cell lung, melanoma)
nature.com/articles/s41...
nature.com/articles/s41...
nature.com/articles/s41...
Holy 💩!

Today, we see the fruit of 5+ years of teamwork. We have built a map of the neutrophil compartment (mostly in mice - but also humans). It provides a biological structure that focuses on a single immune cell lineage to discover the many ways in which neutrophils "interpret" physiology.

Congrats, Arthur and Ling! 👍

Beautiful paper. Congratulations!

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer - Nature Microbiology Reduced dietary fibre together with mutations in the host mismatch repair machinery promote colon carcinogenesis by increasing inflammation, nitrate-fuelled growth of colibactin-producing Escherichia ...

Studying the impact of diet is fascinating and often challenging. Here the authors implicate a low carbohydrate diet in the increased susceptibility to polyp formation and colorectal #cancer in sensitized mouse models @naturemicrobiol.bsky.social www.nature.com/articles/s41...

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer - Nature Microbiology Reduced dietary fibre together with mutations in the host mismatch repair machinery promote colon carcinogenesis by increasing inflammation, nitrate-fuelled growth of colibactin-producing Escherichia ...

#midweekmicro🔬

Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer

@naturemicrobiol.bsky.social #microsky

www.nature.com/articles/s41...

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Many congratulations, Kyle and Arthur et al. Well done! 👏👏