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Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease A metagenome-informed metaproteomics approach unravels the interplay between the host, gut microbiome, and diet in animal models as well as in human cohorts and identifies disease biomarkers of dysbio...

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Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease

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www.cell.com/cell/abstrac...

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Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection Fachi et al. show that a low-fiber diet worsens CDI by increasing MHC-II in colonic epithelium, promoting pathogenic CD4+ IELs. Acetate from fibers enhances ILC3-derived IL-22 via FFAR2, suppressing M...

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Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection

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www.cell.com/cell-host-mi...

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Interconnected pathways link faecal microbiota plasma lipids and brain activity to childhood malnutrition related cognition - Nature Communications Here, using a multisystem approach, the authors characterize the impact of Moderate Acute Malnutrition (MAM) on the gut-brain axis and its effects on cognitive and microbiome development in one-year-o...

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Interconnected pathways link faecal microbiota plasma lipids and brain activity to childhood malnutrition related cognition

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www.nature.com/articles/s41...

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Gut microbiome signatures of vegan, vegetarian and omnivore diets and associated health outcomes across 21,561 individuals - Nature Microbiology Using 21,561 individuals, the authors present a cross-sectional study of how gut microbiome signatures are associated with dietary intake patterns and with host health outcomes.

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Gut microbiome signatures of vegan, vegetarian and omnivore diets and associated health outcomes across 21,561 individuals

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www.nature.com/articles/s41...

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