New in JHEOR: A US retrospective study found that PIVC-related complications occur in roughly 0.5%-1% of surgical patients, driving significantly higher readmission risks, extended hospital stays, and tens of thousands of dollars in excess costs for both adults and children. jheor.org/article/156489
All-cause healthcare spending in patients with multifocal motor neuropathy.
New real-world study, using Medicare Advantage claims data, highlights the considerable burden associated with multifocal motor neuropathy on patients and the healthcare system. jheor.org/article/1581... #neuropathy #RealWorldData
Bullet-point summary of study
US-based analysis finds that shortening ART restart delays from 32 to 12 weeks results in 88 transmissions averted and lifetime healthcare savings of $101 million by improving viral suppression and CD4 counts. #HEOR #HIV #ART #PublicHealth
While clean-fuel households in Nigeria spend more for cooking energy and respiratory health care than those using polluting fuels, a model-based analysis showed clean fuels to be cost-effective. #CleanFuel #Nigeria #HEOR
Retrospective commercial claims analysis of patients with congenital pulmonary valve disease through age 65 quantifies the lifelong burden. High early hospitalization rates and average cumulative lifetime costs exceeding $2 million by age 65 underscore the need for improved early care. #HEOR
New in JHEOR: A Markov model, evaluating the Canadian fiscal impact of treating inadequately controlled generalized myasthenia gravis with efgartigimod vs current therapies, found reduced lifetime public burden and positive government return on investment. #MyastheniaGravis jheor.org/article/157709
Infographic with Common Health Coalition logo at the top. Text reads, "More Illness, Greater Cost Spotlight Brief: Childhood Immunizations. By 2030, a 1% decline per year in MMR vaccination coverage could result in ~$1.5 billion in annual added costs. $41.1 million in direct medical costs. $947.0 million in public health outbreak response costs. $510.4M in productivity and missed work costs. Website at the bottom of the graphic: www.CommonHealthCoalition.org
New analysis from the Common Health Coalition and researchers at the @yalesph.bsky.social highlights the widespread consequences of declining childhood vaccination coverage. ow.ly/Ox2450YmJtG
This study examined the effect of head and neck cancer (HNC) treatment on household financial vulnerability and potential need for catastrophic income loss protection. HNC carries high morbidity, and treatment can cause serious functional impairment. A cross-sectional simulation used responses from US adults aged 35–64 in the US Federal Reserve 2023 SHED survey. With complete income loss, 16% of simulated patients were insolvent by 3 months, increasing sharply to nearly half by 6 months. Partial income loss substantially reduced insolvency risk, while access to liquid savings further protected households from short-term financial collapse during treatment. Results highlight severe financial vulnerability during HNC care, supporting expanded income protection programs and broader evaluation of cancer-related household hardship.
New in JHEOR: Head and neck cancer treatment causes rapid household insolvency risk, highlighting need for income protection programs, based on simulation using US survey data. jheor.org/article/155597 #HEOR #CancerTreatment #CatastrophicIllness
Novel 1-pill regimen tamps down virus in older adults with HIV, study suggests
The regimen combining bictegravir and lenacapavir provided similar viral suppression as multi-pill antiretroviral therapy
www.cidrap.umn.edu/h...
Washington University's acquisition of St. Louis College of Pharmacy, if approved by government regulators, would establish the WashU St. Louis College of Pharmacy as the university’s 10th academic school.
This study examined antiretroviral therapy switching patterns among treatment-experienced people with HIV to inform shared decision-making and optimize long-term regimen selection.
New Optum claims analysis finds that treatment-experienced people with HIV receiving bictegravir/emtricitabine/tenofovir had greater regimen durability and lower switching risk than other antiretroviral therapies, including Medicare Advantage populations. jheor.org/article/156180 #HEOR #HIV #ART
New modeling study: QALY-based cost-effectiveness analyses undervalue life-extending Duchenne muscular dystrophy treatments, favoring delayed progression over mortality gains and highlighting limitations of traditional value frameworks. #HEOR #qalys #musculardystrophy jheor.org/article/156118
New in JHEOR: A lifetime Markov model showed that adjuvant trastuzumab-emtansine is cost-effective and cost-saving vs trastuzumab for HER2+ breast cancer with residual disease in Colombia. jheor.org/article/156056 #HEOR #breastcancer
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Dr. Camara Phyllis Jones is an American physician, epidemiologist, and anti-racism activist who specializes in the effects of racism and social inequalities on health.
Dr. Jones’ work focuses on naming, measuring, & addressing the impacts of racism on health & wellbeing.
#BlackHistoryMonth
To lower overall health care spending, spend more on primary care, a new report argues www.marketplace.org/story/2026/0...
Price competition within government procurement can exacerbate fraud by selecting on low-cost, fraudulent firms. New evidence from Medicare durable medical equipment, from Renuka Diwan, Paul Eliason, Riley League, Jetson Leder-Luis, Ryan McDevitt, and James Roberts www.nber.org/papers/w34802
Patient interviews within a phase 1/2 open-label trial show that DTX401 gene therapy reduces treatment burden and improves quality of life in adults with glycogen storage disease type Ia (GSDIa). jheor.org/article/155666 #HEOR #GSDIa #genetherapy
Amicus brief filed against RFK Jr attacks ‘shared clinical decision-making’
Groups are warning that recent federal actions weakening routine childhood vaccination recommendations pose an urgent threat both for children and the public’s health.
www.cidrap.umn.edu/c...
Post-Dobbs abortion bans disproportionately associated with increased PPD risk among individuals in low-SES communities, amplifying existing health disparities. #postpartum #depression #Dobbs #abortion
Large share of older US adults haven’t had a recent flu or COVID vaccine, poll finds
Of adults ages 50 and older, 42% remain unvaccinated.
www.cidrap.umn.edu/c...
I am hearing that RFK Jr.’s minions are going to go after HPV vaccines. I’ve got problems with these people and now you’re going to hear about them, first from a personal perspective and then from a professional one.
It all boils down to this: WE HAVE A SAFE VACCINE THAT PREVENTS CANCER.
Universal self-collection of cervical samples may hike #HPV screening rates
Offering self-collection to all women can improve health equity and speed the global elimination of cervical cancer, the authors say.
www.cidrap.umn.edu/h...
New study in JHEOR assesses the cost-effectiveness of the TYRX antibacterial envelope in preventing cardiac implantable electronic device infections in Spain, showing it is cost-effective or cost-saving across device types. #HEOR #InfectionControl #Spain #MedicalDevices jheor.org/article/154974
New study evaluating real-world Medicare data shows reduced healthcare utilization after pimavanserin initiation in newly diagnosed, treatment-naïve Parkinson’s disease psychosis patients. jheor.org/article/154805 #Parkinsons #pimavanserin #HEOR
Remember that exploitative and unethical clinical trial of HepB vaccine in Guinea-Bissau that RFK Jr. funded?
It’s been cancelled.
📊 This new interactive from USC Schaeffer lets researchers and policymakers explore how medical spending for Medicare beneficiaries with #dementia has changed across time, states, demographics and care settings.
Explore the data here ⤵️
