Bridging the lipid divide: archaeal ESCRT-III binds phosphoinositol and polarises the cytokinetic membrane www.biorxiv.org/content/10.6...

Just published in @science.org 🚀

By controlling how cells align, we show that living nematic tissues can be programmed to generate forces and fold into predictable 3D shapes.

A new platform for tissue engineering and the design of smart active materials! 🫆

www.science.org/doi/10.1126/...

We offer a PostDoc position for a fully funded project on lipid-encoded #lipidtime protein quality-control checkpoints at the Golgi: great collaborators, excellent working & living conditions & benchspace with a view ;) Please share and repost!

FEBS Press DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non-replicating cells tolerate genotoxic stress, constitutively replicating...

Tardigrades resist heavy DNA damage by actively repairing such lesions & expressing DNA-protective proteins. Yet, they are not immortal. How & why do they die? @morielab.bsky.social now shows that their Achilles' heel is DNA replication: duplicating your DNA... will kill you doi.org/10.1111/febs...

I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...

When DNA damage responders are not only that: @MorieLAB.bsky.social shows that, without ATM, one master kinase responding to DNA damage, the Golgi is markedly deployed. ATM phosphorylates Golgi substrates to limit Golgi extension, which matters for Golgi cargo maturation: doi.org/10.64898/202...

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density. Lipid-CLEM, now out in @natcellbio.nature.com brought to you by @mathilda95.bsky.social changes that:
www.nature.com/articles/s41...

www.biorxiv.org/content/10.6... Amazing work by Kris and gang! For the first time we have been able to image division ring components live in Sulfolobus. And guess what - CdvA is asymmetrically inherited.

#CIBpapers

A new publication in EMBO J by Dr. Jorge Montesinos (@cib-csic.bsky.social) identifies a new mechanism that enables cells to regulate the energy they produce and opens avenues for future research into neurodegenerative and metabolic diseases.

🔗t.ly/eeyDs

Meanwhile, Spain's massive investment in renewables is paying dividends now: with prices for Spanish industry and consumers low and stable compared with other European economies.

www.ft.com/content/ac77...

With Eugene Koonin, we propose a concept of “the selfish ribosome”, under which evolution of life is viewed as a ribosomal takeover, where the ribosome evolved to consume most of the cell’s resources, while other cellular componentry ensures the propagation of the ribosome. arxiv.org/abs/2602.23268

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).

A brief 🧵 (carried over from the old place)

Can't miss this amazing study on the ribosome structure of the Haloferax archaeon 👏🏼👏🏼👏🏼!! Congrats to my good friend @diorgeps.bsky.social and all the other ppl involved!!

Congratulations!! 👏🏼👏🏼👏🏼

Great job!! 👏🏼👏🏼👏🏼
Congratulations to all authors!

Hello epithelial mechanics fans!! I’m Juanma @juanmagararc.bsky.social 👋 I work on cell mechanics (see celldynamicslab.com) and use Flipper-TR FLIM to probe membrane biophysics in cells.

Join me on this tour about Flipper: what it measures, strengths, advice, cool case studies, and cute drawings!

Espadas, J., Souza, D. P., Hakala, M., García-Arcos, J. M., Tran, J., Kumar, A., Marcuello, C., Merino, A., ..., Toret, C. P., & Roux, A. (2025). Molecular basis for cellular compartmentalization by an ancient membrane fission mechanism. bioRxiv. #EpithelialMechanics
buff.ly/OQv9qMw

finishing with a path to multicellularity via ultrastructure complexity #cellbiologyofeukaryogenesis @sbcf.bsky.social

a big thank you to all speakers!

from viruses to lipid transfer and multiple symbiosis in early eukaryotes...
#cellbiologyofeukaryogenesis @sbcf.bsky.social

next step about ins and outs of symbiosis in eukaryogenesis
#cellbiologyofeukaryogenesis @sbcf.bsky.social

fantastic start for our Eukaryogenesis meeting with a vivid overview of membrane remodelling systems in Archae!

Today at 17:00 CET - the first #MembraneTrafficking seminar of 2026.
Giovanni D’Angelo (EPFL) and Sean Munro (MRC-LMB), explore protein trafficking, retention, and sorting at the Golgi.
Join us for exciting discussions about the best organelle!
Details at felixcampelo.wixsite.com/membranetraf...

Join us this Thursday (Jan 29) at 5pm CET for the first #MembraneTrafficking seminars of 2026, featuring two outstanding scientists, Giovanni D'Angelo (EPFL) and Sean Munro (@cellbiol-mrclmb.bsky.social), and the shared topic of protein trafficking, retention & sorting at the #Golgi 🥞

A reminder to sign up for the 2026 EMBO archaeal meeting im Cambridge: meetings.embo.org/event/26-arc.... Registration is open. We are looking forward to hosting you!

Membrane microdomains are crucial for Mycobacterium marinum EsxA-dependent membrane damage, escape to the cytosol, and infection Sterol-rich microdomain accumulation at the MCV is crucial for Mm-induced damage and infection in D. discoideum and BV-2 cells.

🚨 Want to know how we demonstrated the importance of sterol-rich membrane microdomains for M. marinum infection?

Check out our latest paper published in Science Advances 👇
www.science.org/doi/10.1126/...

✨ Big thanks to everyone, especially Cristina Boehm-Bosmani, @soldatilab.bsky.social ! ✨

Dynamic protrusions mediate unique crawling motility in Asgard Archaea (Promethearchaeota) Crawling motility is a hallmark of eukaryotic cells and requires a dynamic actin cytoskeleton, regulated adhesion, and spatially organized signalling pathways1–3. Asgard archaea (phylum Promethearchae...

1. As we recently joined BlueSky, we want to repost this story for all newcomers!

We sat down with @radler92.bsky.social to get more insight into the unique videos from his recent preprint on Promethearchaeota (formerly Asgard archaea).

doi.org/10.1101/2025...

(Videos and info below)

Are you a long-time fan of Archaea, an extremophile-phile, or are you simply curious?

Either way, we have good news.
We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July.

Sign up: meetings.embo.org/event/26-arc...

We look forward to seeing you in Cambridge, UK.

Please repost!

Congrats Omaya!! 👏🏼👏🏼👏🏼👏🏼

An Asgard Archaeon (Lokiarchaeum ossiferum) growing and retracting its arms

Collaboration for Understanding | Searching for the Asgards YouTube video by Schmidt Ocean

And ‘Searching for the Asgards’ the movie: www.youtube.com/watch?v=mgmE...