#CIBpapers
A new publication in EMBO J by Dr. Jorge Montesinos (@cib-csic.bsky.social) identifies a new mechanism that enables cells to regulate the energy they produce and opens avenues for future research into neurodegenerative and metabolic diseases.
🔗t.ly/eeyDs
#CIBpapers
The 3D extracellular environment “reprograms” #leukemia cells by persistently altering their nucleus, genetic activity, and behavior.
A new paper was published by the group of Dr. Javier Redondo in Cell Reports Physical Science.
🔗t.ly/tHGZ8
#CIBpapers
Our colleague Rodrigo Sánchez-Tarjuelo (Flow Cytometry) writes the book chapter "The genetic regulation of immune cells upon activation".
It's been published in the Advances in Genetics volume "Genetic Regulation of Immune Response Pathways".
🔗t.ly/x_SJ9
#CIBpapers
Researchers at the @cib-csic.bsky.social present a new bacterium capable of transforming plastic waste into high-value bioproducts
More info 🔗cib.csic.es/news/research/researcher...
Biomolecular condensates of the central bacterial division protein FtsZ with the antagonist of cell division ring formation SlmA in crowded media, some time after triggering polymerization by GTP addition, in the presence of a benzodioxane-benzamide that interferes with the cell division machinery.
#CIBpapers
Researchers at @cib-csic.bsky.social, together with @iqf-csic.bsky.social, Università degli Studi di Milano, and UTHealth-Houston, identified a new mechanism related to biomolecular condensation processes that may be useful in combating bacteria resistant to antibiotics.
🔗t.ly/6JFBP
#CIBpapers
The collaboration of four scientific teams from the @csic.es, led by Eduardo Rial (@cib-csic.bsky.social), has allowed for the identification of dichloroacetate (DCA) as a possible drug for the treatment of viral respiratory diseases.
🔗t.ly/XaZaE
#CIBpapers
Un trabajo publicado por el grupo de la Dra Nuria Campillo en el @cib-csic.bsky.social muestra que ciertos fármacos actúan como moduladores de la localización del receptor D2 de dopamina (D2R) mediante la interrupción de la interacción NCS-1.
Léelo aquí 🔗t.ly/E8ylz
#CIBpapers
The group of Jorge Barriuso at @cib-csic.bsky.social has developed an innovative method to produce bioplastics from agro-industrial waste using a synthetic microbial consortium. The work has been published in ACS Sustainable Chemistry & Engineering.
More info 🔗t.ly/jBN6L
Adhesión celular mediada por los receptores de integrina RGD. A la izquierda, las integrinas interactúan con proteínas canónicas de la matriz extracelular (MEC) que contienen RGD para regular la adhesión celular a la MEC. Se indican los componentes representativos de la MEC (fibronectina, fibrinógeno, colágeno, laminina, proteoglicano y elastina). A la derecha, las integrinas interactúan con los contra-receptores de integrina no canónicos que contienen RGD (RGD-ICR) para regular la adhesión intercelular. Se enumeran los receptores de integrina RGD (integrinas α2β1, α5β1, αIIbβ3, αvβ3 y avβ5) y los RGD-ICR (ADAM15, CDH5, CDH6, CDH17, endoglina y L1CAM) objeto de esta revisión.
#CIBpapers
"The emerging role of human transmembrane RGD-based counter-receptors of integrins in health and disease".
A review published by our researcher Carmelo Bernabeu, in the journal Cell Mol Biol Lett
Lee el artículo aquí 🔗cmbl.biomedcentral.com/articles/10.1186/s11658-...
Front Cover: Glycans and Chirality: Stereoselectivity at the Core of DC-SIGN's Recognition. A Novel View of the Optimum Minimal Ligand Epitope. J. Daniel Martínez, Reyes Núñez-Franco, Pablo Valverde, Sandra Delgado, Ana Ardá, Jesús Jiménez-Barbero, Gonzalo Jiménez-Oses, F. Javier Cañada. https://chemistry-europe.onlinelibrary.wiley.com/toc/15213765/2025/31/37
#CIBpapers
A team led by Javier Cañada (@cib-csic.bsky.social) has uncovered the minimal structural scaffold that enables the immune lectin DC-SIGN to recognize sugars with high stereoselectivity.
🔗chemistry-europe-onlinelibrary-wiley-com.csic.idm.oclc.org/doi/epdf/10.1002/chem.20...
#CIBpapers
The group led by Auxi Prieto at @CIB_CSIC has made a significant advance in producing sustainable #bioplastics from food industry wastewater.
More information ➡️www.cib.csic.es/news/research/sustainabl...
#CIBpapers
Un trabajo del grupo de César Llave en Plant Cell Environ muestra que al sobreexpresar BIR1 en Arabidopsis se activa su sistema inmune aún en ausencia de patógenos, causando muerte celular dependiente de SOBIR1 y EDS1.
🔗onlinelibrary.wiley.com/doi/10.1111/pce.70036
#CIBpapers
A team from @cib-csic.bsky.social discovered that deferiprone, used to eliminate excess iron in the body, protects retinal #photoreceptor cells from degeneration.
🔗https://f.mtr.cool/lsxdqioyig
#CIBpapers
@tornerolab.bsky.social at @cib-csic.bsky.social has unveiled one of the mechanisms used by eukaryotic cells to detect the most frequent natural #mutation in #DNA.
🔗https://f.mtr.cool/dvxaprqbng
#CIBpapers
A team led by Nuria Campillo's group at @cib-csic.bsky.social has developed an innovative IA strategy to design therapeutic molecules from scratch, even with limited data.
🔗https://f.mtr.cool/ihgnvvcguy
#CIBpapers
Provided an atomic model for FAK force activation characterizing all interactions of the force transmitting tether to FAK. A work in Cell Commun Signal by Daniel Lietha
🔗https://f.mtr.cool/rermynrkyn
#CIBpapers
A new mechanism involved in disseminating acute lymphoblastic leukemia has been revealed.
A study led by Dr. Javier Redondo published in Biomed & Pharmacother.
More info➡️https://s.mtrbio.com/nahdkljxne
