Don't miss the #GordonConference on 𝑺𝒊𝒏𝒈𝒍𝒆-𝒎𝒐𝒍𝒆𝒄𝒖𝒍𝒆 𝑨𝒑𝒑𝒓𝒐𝒂𝒄𝒉𝒆𝒔 𝒕𝒐 𝑩𝒊𝒐𝒍𝒐𝒈𝒚, organized by #KevinWelsher & me:
⏰ June 28 - July 3, 2026
🌍 in the Swiss Alpes (✈️ Geneva)
✅ APPLY now: deadline May 31.
We're 75% booked: register today & be there! 🙌
🕳️ 🧬🧪🧫 🔬🟩🟥🟩🟥🏋️‍♀️💥🪤 🍩 ... you get it... 😁

We're super excited about the speaker line-up at this GRC, featuring e.g. keynotes from @melikel.bsky.social, #ShuoHuang, #ScottBlanchard, @ceesdekker.bsky.social – and more talk slots are still available!
www.grc.org/single-molec...

What if cells have undiscovered methods for managing their internal logistics? Our recent work (@cathygalbraith.bsky.social, James A. Galbraith, @sciencethecat.bsky.social & myself) challenges existing views on intracellular transportation 🔗 lnkd.in/dhMDgY5Q

Congratulations and best of luck with the move!

Illustration of a fly and cellular structures connected by red and black thread-like lines inside a circle with a blue dot labeled 'TF' and text 'AlHaj Abed LAB' and 'Postdoctoral Researcher (m/w/d) Max Planck Institute of Immunobiology & Epigenetics'

Text listing tasks in AlHaj Abed lab including Hi-C and Micro-C analysis, adapting multi-way contact genomic tools for Drosophila, building visualization framework for Pore-C data, image analysis, and programming in R and/or Python

Text listing reasons to appreciate the Max Planck Institute in Freiburg including collaborative culture, core facilities, grants, scientific network, international diversity, public benefits, family support, relocation service, social life, and location, with a website link

Logo of the Max Planck Society; below text inviting to join the AlHaj Abed Lab with application deadline April 8, 2026, and a project website URL

🚨 Postdoc in 3D genome architecture – join the @jumanaaha.bsky.social lab at the MPI-IE, Freiburg (🇩🇪)

The wonderful lab of Jumana AlHaj Abed is pushing the limits of how chromosomes fold and interaction – and we need someone who can code, image, & think across scales.

Apply here: s.gwdg.de/9c8838

Spectral multiplexing is typically limited to 4-5 channels. Our new preprint introduces a framework that utilizes DNA barcoding and signal tuning to enable robust spectral unmixing and ground-truth benchmarking to achieve 15-plex subcellular profiling without cycling
www.biorxiv.org/content/10.6...

@mukherja.bsky.social work on RNAPII clusters is in print today: www.nature.com/articles/s41...
Congrats!
TLDR: RNAPII clusters represent transcriptonally engaged molecules at single genes, not super-stochiometric assemblies.
Please check it out and see the the thread below for a summary.

Congratulations. Well deserved!

Baby KJ One Year Later: Gene-Editing Breakthrough Update YouTube video by The Children's Hospital of Philadelphia

Baby KJ update! 🧪
He's looking so good now 🥹 Hope this little guy continues to thrive and that the team at CHOP gets to save more kids like him.🫶

youtu.be/dMY-nYMeis4?...

Seminar announcement for Max Planck Seminar Freiburg titled 'Super-resolution imaging of chromatin in health and disease' with date, time, location, and speaker Melike Lakadamyali from University of Pennsylvania Philadelphia USA

This Friday (today), we’re pleased to welcome Melike Lakadamyali (@melikel.bsky.social) from @upenn.edu.

If you are interested in Super resolution microscopy, cytoplasmic and nuclear organization with a focus on biophysics, then do not miss Prof. Lakadamyali talk in our lecture hall at 13:00. 🤗

Congratulations! So well deserved!

Congratulations! Incredibly well deserved!

Seeing Chromatin Scaling with Cell Size, from Interphase to Mitosis - FocalPlane Seeing Chromatin Scaling with Cell Size, from Interphase to Mitosis -

Melike Lakadamyali @melikel.bsky.social, Jérôme Solon and Manuel Mendoza @longchrom.bsky.social share the behind the paper story of their research interrogating how chromosome compaction scales with cell size using a combination of live confocal microscopy and 3D STORM.

Seeing Chromatin Scaling with Cell Size, from Interphase to Mitosis - FocalPlane Seeing Chromatin Scaling with Cell Size, from Interphase to Mitosis -

Thanks to @focalplane.bsky.social for the invitation to highlight our recent @biophysj.bsky.social paper! With @melikel.bsky.social and Jérôme Solon, we combined super-resolution and live imaging to connect interphase chromatin organisation to mitotic chromosome compaction across cell sizes.

EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond.

We extend our deepest condolences to his family, friends, and colleagues.

www.embl.org/news/people-...

Feel better Rita!

Visualization of lysosomal membrane proteins by cryo electron tomography - Nature Communications Lysosomes are vital for cellular health and linked to many diseases. Here, authors use cryo-ET to image intact lysosomes and resolve lysosomal protein structures, providing a platform to advance the s...

I’m sad to miss the exciting talks at Cellbio! This is indeed a very exciting area of research. See also this fantastic paper by my Penn colleagues on this topic: www.nature.com/articles/s41...

Congratulations! So well deserved!

So proud to watch Jana turn a side quest into an entire research programme. Couldn’t imagine a more well-deserved outcome. 😍

The mighty yeast reveals what we believe are general principles of centromere evolution!

Behind the curtain: communities.springernature.com/posts/counti...

#MEvoSky 🧪🌎

Last call for Les Houches! Apply now or never! ;) (ok, in 2 years again then) and share with your friends.

Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...

Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...

Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Erdinc Sezgin to Receive 2026 Early Independent Career Award
www.biophysics.org/news-room/er...

Congratulations @jiexiaolab.bsky.social . This is so well deserved.

Jie Xiao to Receive 2026 Carolyn Cohen Innovation Award
www.biophysics.org/news-room/ji...

Sarah Veatch to Receive 2026 Agnes Pockels Award in Lipids and Membrane Biophysics buff.ly/AdSMhCT

Congratulations to @ceesdekker.bsky.social . This is so well deserved!

Cornelis (Cees) Dekker to Receive the 2026 Kazuhiko Kinosita Award in Single-Molecule Biophysics buff.ly/fIexyZu

French-German WE-Heraeus-Seminar "Fluorescence markers for advanced microscopy : From photophysics to biology - 2026" March 15-20 2026, Les Houches, France

Please share: The application for Les Houches is open (until Oct 31)

fluorescenceleshouches.wordpress.com

*This is for you, if you ever wanted to learn all about fluorescence markers & how to apply them for your biological research!*

PS: no fees this year, you just need to get there, that's all!

Head of Scientific Instrumentation Workshops EMBL is a world leader in scientific research and at the forefront in the development of cutting-edge technologies. It operates across six sites in Heidelberg (headquarters), Barcelona, Cambridge, Gre...

@embl.org Heidelberg is looking for a new Head of Scientific Instrumentation! This is an exciting opportunity at the interface between scientific research and technology development, overseeing our mechanical and electronic workshops!
embl.wd103.myworkdayjobs.com/en-US/EMBL/d...