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Posts by Finn McQuaid

Budding infectious disease modellers:

We're running our intermediate-level infectious disease modelling short courses at the London School of Hygiene and Tropical Medicine. Each course is 4 days, and we're running them over the first two weeks of September.

6 days ago 5 7 1 0
After three years of conflict, Sudan is facing
the world’s largest humanitarian crisis. 

21 million people require urgent health assistance.

After three years of conflict, Sudan is facing the world’s largest humanitarian crisis. 21 million people require urgent health assistance.

WHO calls for the protection of health care and safe access to everyone in need.
 

Above all, people in Sudan need peace.

WHO calls for the protection of health care and safe access to everyone in need. Above all, people in Sudan need peace.

Health needs in Sudan
- Around 4 million people are acutely malnourished
- Diseases such as malaria, dengue and measles are spreading
- Close to 40% of health facilities are non-functional

Health needs in Sudan - Around 4 million people are acutely malnourished - Diseases such as malaria, dengue and measles are spreading - Close to 40% of health facilities are non-functional

WHO’s Response in Sudan
- WHO helped contain two cholera outbreaks
- 4.1 million patients treated in hospitals, primary health centres & mobile clinics
- 46 million children and adults vaccinated against cholera, polio, diphtheria, measles and rubella
- 118 000 severely malnourished children treated in stabilization centres 
- 3300+ metric tons of medical supplies and medicines delivered

WHO’s Response in Sudan - WHO helped contain two cholera outbreaks - 4.1 million patients treated in hospitals, primary health centres & mobile clinics - 46 million children and adults vaccinated against cholera, polio, diphtheria, measles and rubella - 118 000 severely malnourished children treated in stabilization centres - 3300+ metric tons of medical supplies and medicines delivered

Three years of war in #Sudan have disrupted basic services, displaced millions and devastated the health system.

Sudan is facing the world’s largest humanitarian crisis marked by disease, hunger, displacement & despair.

Sudan's people need peace.

#3YearsTooLong

1 week ago 99 58 2 1
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Trade-offs in diagnostic algorithm, population coverage, and duration of community screening for tuberculosis: A modelling study In a mathematical modelling study, Katherine Horton and colleagues assess different tuberculosis (TB) community screening approaches and their estimated effects on TB incidence and mortality over ten ...

In this mathematical modelling study, Katherine Horton & co assess #TB community screening approaches & their estimated effects on TB incidence & mortality, concluding that methods that capture both infectious & non-infectious TB are needed to achieve sustained case reductions🧪
plos.io/4tuD2SM

2 weeks ago 6 3 0 1
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Massive devastation following the Israeli strikes across Lebanon.

Homes destroyed. Communities shattered. Many lives lost.

Children reported among the victims.

Civilians, in particular children, must be protected at all times, and international humanitarian law must be fully respected.

1 week ago 59 49 0 6
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#Post-tuberculosis lung disease: no ICD code, no problem? Zintle was aged 23 years when she presented for the first time to our clinic in South Africa. Her oxygen saturation was 59% on room air, and for months she had been too short of breath to leave her ho...

Post-TB lung disease is real—but still invisible in global health systems. Read the full article to understand why this gap matters. #PostTBcare @lshtm.bsky.social @nihr.bsky.social @suhealthsci.bsky.social
www.thelancet.com/journals/lan...

2 weeks ago 7 6 0 0

New study led by @alexandra-richards.bsky.social.

Reducing men’s TB risk and improving treatment access could have big impacts on #TB incidence and deaths for men, women, and children.

www.nature.com/articles/s43...

@kchorton.bsky.social
@uofgshw.bsky.social
@lightontb.bsky.social

3 weeks ago 7 9 0 1
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Climate change and tuberculosis: an analytical framework Climate change is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in w...

🌐 Position paper
Climate change and tuberculosis: an analytical framework shorturl.at/qGB9w

Massive thanks to all our authors working in this area!

4 weeks ago 2 1 0 0
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Claire Calderwood: integrated health screening for tuberculosis “Respiratory medicine is deeply connected to social and structural determinants of health in terms of the diseases that we try to prevent and we treat. I think that connection to people's lives and so...

Claire Calderwood: integrated health screening for tuberculosis - The Lancet www.thelancet.com/journals/lan...

4 weeks ago 5 3 0 0

Our analysis of #TB exposure and transmission patterns is now in @pnas.org. @petedodd24.bsky.social and I found a majority of TB transmission globally is attributable to contact with adult men, while contributions to transmission by age are more variable across regions.
www.pnas.org/doi/10.1073/...

1 month ago 10 8 0 0
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Gamification meets TB -- a free arcade game for World TB Day!!

Jason Madhosingh's wife is a TB doc, and he built this game in her honor!

You can shoot at Mycobacterium tuberculosis and prevent them from destroying lungs!

Please share and make it go viral!!

tberadicator.com

1 month ago 35 21 3 8
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🗞️ Recent study with @lshtm-tbmod.bsky.social modelled the potential impact of funding cuts to TB #PublicHealth initiatives from international donors

Already implemented USAID cuts could cost $7.5 billion (USD) for healthcare systems & people living with TB

Read 🔽
www.lshtm.ac.uk/research/cen...

1 month ago 11 11 0 1
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@tb-lshtm.bsky.social amazing #StudentAmbassadors 2025-26 highlight why everyone interested in TB should join us for these two amazing events marking #WTBD2026
PS: they are both free and open to all!
@ucltb.bsky.social @mrcunitgambia.bsky.social @mrcctu.bsky.social @lshtm-tbmod.bsky.social

1 month ago 10 7 0 0
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The potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries: A modeling study In a modelling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of Tuberculosis in low- and middle-income ...

With Nick Menzies and @lshtm-tbmod.bsky.social, our new modeling study estimated how reductions in donor funding could affect the economic burden of #TB on patients, especially among the poorest households journals.plos.org/plosmedicine...

1 month ago 5 5 0 1
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Estimating the population impact of new tuberculosis vaccines depending on efficacy against infectious asymptomatic tuberculosis: A modelling study Hira Tanvir and colleagues estimate the potential impact of new tuberculosis vaccines under three scenarios of efficacy and conclude that to achieve the greatest impact, vaccines must prevent asymptom...

Delighted to share my first co-authored paper, now published in @PLOSMedicine

In our modelling study, we show that the projected population-level impact of new TB vaccines may depend on their efficacy in preventing infectious asymptomatic TB.

Read more: journals.plos.org/plosmedicine...

1 month ago 3 1 1 0
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Estimating the population impact of new tuberculosis vaccines depending on efficacy against infectious asymptomatic tuberculosis: A modelling study Hira Tanvir and colleagues estimate the potential impact of new tuberculosis vaccines under three scenarios of efficacy and conclude that to achieve the greatest impact, vaccines must prevent asymptom...

Our recent modelling study found that the estimated impact of new TB vaccines depends on the efficacy to prevent infectious asymptomatic TB. Read more in our paper out now in @plosmedicine.org!

journals.plos.org/plosmedicine...

1 month ago 15 13 1 0
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The potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries: A modeling study In a modelling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of Tuberculosis in low- and middle-income ...

In this modeling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries 🧪 #MedSky #TB
plos.io/4ryyBFX

1 month ago 15 15 0 2
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📈 Our @lshtm.bsky.social and @ukhsa.bsky.social short course introduces you to mathematical modelling for #InfectiousDisease

Learn the basic methods for modelling infections and control programmes in #PublicHealth

Runs from 15-27 June 2026

Apply 🔽
www.lshtm.ac.uk/study/course...

2 months ago 4 4 0 0
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The global lung health community is heading to Rio, and submissions for #UnionConf2026 are now open.

This is your moment to showcase research, innovation and community impact on the world stage.
Deadline: 9 April 2026 (23:59 CEST)
Learn more and submit: https://tinyurl.com/3ve8axf3

2 months ago 1 1 1 0

@tb-lshtm.bsky.social @lshtm-tbmod.bsky.social @kncvtbplus.bsky.social

2 months ago 1 0 0 0
The effects of war on digital adherence technology engagement for TB treatment in Ukraine SUMMARYBACKGROUNDThe Russian invasion of Ukraine in February 2022 has disrupted TB care. We examine the effects of the war on people with drug-susceptible TB (PWTB) and health care worker (HCW) engagement with a digital adherence technology (DAT).METHODSWe conducted a cluster-randomised trial of a DAT intervention in Ukraine. In the intervention arm, PWTB received a pillbox with a daily treatment reminder. Pillbox openings were captured real-time onto a platform, accessed by HCWs who could add manual doses where relevant. We compared DAT engagement in pre-, early-, and later-war periods.RESULTSFrom June 2021 to 2022, 816 PWTB (32% women, median age 44 years) were enrolled. DAT engagement varied across regions and time period, with a decline in engagement post-February 2022. PWTB DAT engagement was 78%–84% of treatment-days. There was a three- to four-fold increase in unknown dose or delays in manual reporting of adherence (>7 days) post-February 2022 versus pre-war in Mykolaivska and Donetska oblasts and a two-fold increase in Odeska, Lvivska, and Zakarpatska oblasts.CONCLUSIONThe war significantly disrupted DAT engagement, particularly in regions heavily affected by the conflict. Reduced engagement was likely due to migration and communication challenges. There is a critical need for resilient TB care in conflict settings.

We know conflict & crises have severe repercussions for TB; health system disruptions, displacement, food insecurity... In our latest paper we examine the effects of war in Ukraine on engagement with a digital adherence tech by people w TB & health care workers journals.theunion.org/content/ijtl...

2 months ago 10 8 1 0
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Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study Alvaro Schwalb and colleagues conducted a mathematical modelling study to estimate the global burden of viable Mycobacterium tuberculosis--that which can cause disease and be transmitted--to help guid...

1/📢 In our new publication, we estimate that in 2022, 134 million people worldwide had a recent Mycobacterium tuberculosis (Mtb) infection and were at high risk of progressing to TB disease. Read the full paper in PLOS Medicine (tinyurl.com/mtbinfection). #TBSky

2 months ago 37 25 2 2
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Estimating the global burden of viable Mycobacterium tuberculosis infection: A mathematical modelling study Alvaro Schwalb and colleagues conducted a mathematical modelling study to estimate the global burden of viable Mycobacterium tuberculosis--that which can cause disease and be transmitted--to help guid...

In this mathematical modeling study, Alvaro Schwalb and colleagues estimate the global burden of viable Mycobacterium tuberculosis—that which can cause disease and be transmitted—to help guide disease prevention efforts 🧪 #tuberculosis #MedSky
plos.io/4aqzIQV

2 months ago 11 6 0 2
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Insights on the implementation strategies for a potential new tuberculosis vaccine in South Africa Several tuberculosis (TB) vaccines intended for adults and adolescents are in late-stage clinical trials, but there is limited research into how a new TB vaccine would be introduced. South Africa is a...

Our new paper on strategies for implementing a potential new #TB #vaccine in South Africa is now published in @plosglobalpublichealth.org!

doi.org/10.1371/jour...

2 months ago 7 10 1 0
postdoc_ad_jan2026_final.pdf

#tuberculosis #modeling #fellowship with lovely & great people at Johns Hopkins (deadline 31 January) drive.google.com/file/d/12lK8...

3 months ago 2 1 0 0

I am extremely confused as to why the UK government and police are saying Grok’s mass-scale CSAM generation is an issue for Ofcom.

This isn’t about X failing to moderate CSAM, which is an Online Safety Act issue. It is about the company and its technology being actively involved in its generation.

3 months ago 3840 971 134 58
Mycobacterium tuberculosis complex Strain Discordance Among People With Tuberculosis and a History of Household Contact, a Systematic Review and Meta-Analysis Background: In this systematic review of molecular epidemiology studies, we describe the prevalence of Mycobacterium tuberculosis complex strain discordance amo

NEW PREPRINT!

We systematically reviewed molecular epidemiology studies looking at strain discordance in pairs of people with TB disease and history of household contact

We found 30 studies from 18 countries. Excluding 4 studies at high risk of bias, we had data on 1544 household case pairs

[1/n]

4 months ago 29 13 2 3
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Evaluation of economic strengthening in South Africa and its impact on HIV, sexually transmitted infections, and teenage births: A modelling study Using a modelling framework, Leigh Johnson and colleagues predict limited effects of economic strengthening interventions that aim to reduce HIV, sexually transmitted infections and teenage births in ...

South Africa has made much progress in reducing poverty and income inequality over the last 30 years. But what does this mean for HIV, STIs and teenage pregnancy? Our new study assesses this: dx.plos.org/10.1371/jour...

4 months ago 2 1 0 0
Social Inequalities in Infectious Disease Dynamics: a Symposium and Workshop

Symposium & workshop on inequalities in infectious disease dynamics at LSHTM in April 2026. We aim to will bring together leading researchers and practitioners to share ideas, discuss recent advances, and reflect on future directions. Details & application: iddconf.org/lshtm-sympos... Closing 21 Jan

4 months ago 24 23 1 0
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Climate change and tuberculosis: an analytical framework Climate change is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in w...

🗞️ ICYMI: recent framework led by @cfmcquaid.bsky.social & members at @lshtm.bsky.social looked at impact of climate change on the #TB epidemic

Framework shows why TB needs to be considered a climate-sensitive disease & the steps required

Read paper 🔽
www.thelancet.com/journals/lan...

4 months ago 2 2 0 0
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Tuberculosis- learning about experience with nutritional supplementation (TB LENS): Perspectives on a nutritional supplementation for persons with TB and their household contacts Undernutrition is a major driver of the tuberculosis (TB) epidemic, with one in five TB cases worldwide attributable to undernutrition. Nutritional interventions may reduce TB incidence and mortali...

Everyone in TB talks about “nutrition matters.”

But what happens when you actually ask households with TB what kind of nutritional support works for them?

We did exactly that through the TB LENS qualitative study in South India.

tinyurl.com/mr42k9k8

4 months ago 6 2 1 0