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Posts by Leela Ghimire

Unbelievably proud of the work that everyone has put into this paper. Really grateful for such fab colleagues! Mycobacteria continue to be (subjectively) the most interesting bacteria ๐Ÿคญ

3 weeks ago 21 8 1 0
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The Protein Data Bank (#PDB) has reached a new milestone: 250,441 entries in the archive, a record since its founding in 1971, all thanks to the efforts and contributions of the structural biology community.

โฌ‡๏ธ more โฌ‡๏ธ
www.wwpdb.org/news/news?ye...

#StructuralBiology

1 month ago 19 8 0 0
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Great getting to chat with legendary Fred Anston before his talk at @cbcb-newcastle.bsky.social! Lovely seminar with beautiful structures & fascinating stories about how DNA packs into capsid heads ๐Ÿงฌ๐Ÿงฌ

#StructuralBiology #bacteriophages #NewcastleUni

1 month ago 5 0 1 0

my.corehr.com/pls/uoxrecru...
Two Postdoctoral Research Associates in the Molecular Analysis of Bacterial Outer Membrane Protein Biogenesis

BEN BERKS lab ๐Ÿคฉ

2 months ago 5 7 0 0
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Forged by Iron: Synthetic protein binders to decode bacterial iron transport mechanisms at Newcastle University on FindAPhD.com PhD Project - Forged by Iron: Synthetic protein binders to decode bacterial iron transport mechanisms at Newcastle University, listed on FindAPhD.com

Fully funded four-year PhD position available in my lab!
Combining structural and synthetic biology to understand iron transport.
Deadline 27th of Feb, get in touch for more details!

www.findaphd.com/phds/project...

2 months ago 10 5 0 1

BBSSRC (NEEDL) funded PhD studentship in my lab co-supervised by
@thecopperdoctor.bsky.social and @mycobacterium-ncl.bsky.social
If you're interested in structural biology and membrane transport processes, check out www.findaphd.com/phds/project... deadline 27th of Feb!
Get in touch for more info

2 months ago 7 7 1 2
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Characterising antibacterial toxins in the food-borne pathogen Listeria monocytogenes at Newcastle University on FindAPhD.com PhD Project - Characterising antibacterial toxins in the food-borne pathogen Listeria monocytogenes at Newcastle University, listed on FindAPhD.com

www.findaphd.com/phds/project... interested in bacterial antagonism? PhD opportunity in our team, see below. Please repost!

2 months ago 22 31 1 2
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Here, we show through NMR relaxation dispersion and ribosome assays that restraining flexibility of two central B-strands in domain III of EF-G prevents the increase of a disordered state critical for FA-resistance. Drugging this region thus presents a way to keep fusidic acid active

4 months ago 3 0 0 0

Fusidic acid is one of the last antibiotics active against Methicillin-resistance Staphylococcus aureus. FusB-mediated protection of the drug target Elongation Factor-G is the biggest source of resistance in clinical settings where FusB rescues the translation factor EF-G from FA-stalled complexes

4 months ago 2 0 1 0
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Inhibition of fusidic acid resistance through restricting conformational flexibility in domain III of EF-G | PNAS Fusidic acid (FA) is one of few remaining antibiotics active against Methicillin-resistant Staphylococcus aureus. FusB confers resistance to FA by ...

Happy to see work I contributed to during my MSc at @bioscienceleeds.bsky.social with Jennifer Tomlinsonโ€™s lab out in @pnas.org! Everyone Bluesky-less except @antoncalabrese.bsky.social

www.pnas.org/doi/10.1073/...

#AMR #MRSA #NMR

4 months ago 19 6 1 1

Want to find ways to combat TB? Check out this PhD position ๐Ÿ‘‡

5 months ago 8 17 0 0

The CCP4 Northern Structural Biology Meeting is back again in Newcastle 6-7th November 2025. If you are a structural biologist/biochemist in the North of the UK please register and submit abstracts by this Friday 17th.

nusbf.ncl.ac.uk/ccp4-norther...

6 months ago 20 14 1 2

It was my pleasure! Looking forward to more posts! โœจโœจโœจ

6 months ago 1 0 0 0
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Big thank you to Dr. @cecile-exertier.bsky.social and Dr. Francesca Troilo for SPR training at ITACA-SB CNR in the beautiful Rome. ๐Ÿ‡ฎ๐Ÿ‡น๐Ÿ‡ฎ๐Ÿ‡น๐Ÿ‡ฎ๐Ÿ‡น

Grateful for the opportunity to learn a lot in a couple of days & connect with fellow students!

#ITACA.SB #CNR

6 months ago 4 1 0 1
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