Slice and dice MIT researchers characterize SNIPE, which stands for surface-associated nuclease inhibiting phage entry, which directly protects bacteria from phage, the viruses that infect them, by chopping up…

Slice and dice - chopping up invading #viral #DNA ...

| #SNIPE | #virus | #bacteria | #MicroSky | #bacteriophages | Via @mit.edu

AI uncovers hidden immune defenses inside bacteria Researchers at the Massachusetts Institute of Technology (MIT) have discovered thousands of new proteins that protect bacteria from virus attacks using an AI system called DefensePredictor. What…

Hidden #immune defenses inside #bacteria uncovered by #Ai ...

| #ArtificialIntelligence | #MicroSky | #virus | #bacteriophages | #DNA | #Infections | Via @sciencex.bsky.social

Spaceflight supercharges viruses’ ability to infect bacteria Viruses develop tricks to attack bacteria without the help of gravity

#Spaceflight #supercharges #viruses’ ability to infect #bacteria ...

| #Space | #microbes | #gravity | #ISS | #bacteriophages | #Phage | Via @sciam.bsky.social

Spaceflight supercharges viruses’ ability to infect bacteria Viruses develop tricks to attack bacteria without the help of gravity

www.scientificamerican.com/article/spac...
#microbes&microgravity
“…microbes grown in low gravity changed on a genetic level. The #bacteriophages gained mutations that slightly change the shape and structure of their outer membranes, …helping them grab onto the bacteria they’re attacking.”

A virus hiding inside bacteria may help explain colorectal cancer The gut bacterium Bacteroides fragilis has long presented researchers with a paradox. It has been associated with colorectal cancer, yet it also lives quite happily in most healthy people. A study by…

#Virus hiding inside #bacteria may help explain #colorectal #cancer ...

| #Bacteroides | #microbiome | #bacteriophages | #phage | Via @sciencex.bsky.social

Stunning High-Resolution Virus Blueprint Offers New Hope Against Antibiotic Resistance A detailed 3D map of a bacteria-hunting virus reveals ancient origins and new promise against superbugs.

High-Resolution #virus blueprint offers new hope against #antibiotic resistance ...

| #antibioticresistance | #bacteria | #bacteriophages | #phage | By @universityofotago.bsky.social via scitechdaily .com

🦠 Fighting #AntimicrobialResistance requires innovation!

From natural compounds & synthetic molecules to bacteriophages & clinical adjuvants, multi-pronged strategies are reshaping treatment.

🔗 microbiomecongress.org
📧 vallala@sciinovhealth.com

#Microbiome #GMC2026 #Bacteriophages #Nanotech

Great getting to chat with legendary Fred Anston before his talk at @cbcb-newcastle.bsky.social! Lovely seminar with beautiful structures & fascinating stories about how DNA packs into capsid heads 🧬🧬

#StructuralBiology #bacteriophages #NewcastleUni

Q&A: Researchers create system to engineer synthetic phages Researchers from New England Biolabs and Yale University have created a system for engineering the first fully synthetic bacteriophages that could help with future clinical development of phage therapies.Bacteriophages, also referred to as phages, are naturally occurring viruses that “selectively target and kill bacteria” without infecting human cells, according to WHO. They can be found

❓Could synthetic #bacteriophages be the future of phage therapy?
Researchers at New England Biolabs have have created a system for engineering synthetic phages & created phages meant to target P. aeruginosa.
We spoke with Greg Lohman, PhD, to answer our questions.



vist.ly/4sk9v

Why phage contamination is hard to kill, and how charged nanoparticles could help Bacteriophages are viruses that can kill bacteria through highly specific interactions. While this property can be beneficial in selected applications, bacteriophages represent a serious threat to…

Why #phage #contamination is hard to kill ...

| #Bacteriophages | #viruses | #electrostatic | #pathogens | #antibiotics | Via @sciencex.bsky.social

New in Pathogens and Immunity! Read this exciting summary of the innovative work presented at the 2025 Conference on Bacteriophages: Biology, Dynamics, and Therapeutics. Full summary available here: bit.ly/45WeFEq #Bacteriophages #PhageTherapy #Phages

Biochemistry lab at IU Bloomington finds chemical solution for tackling antibiotic resistance Zhiyu Zang, Olivia Duncan and J.P. Gerdt recently discovered a chemical molecule that can help a bacteriophage overwhelm a bacterium’s immune system, creating a biochemical alternative to antibiotics…

#Biochemistry lab finds #chemical solution for tackling #antibiotic resistance ...

| #antibioticresistance | #bacteria | #fungi | #infections | #Bacteriophages | Via eurekalert .org

Directed evolution of phages in biofilms enhances Pseudomonas aeruginosa control through improved lipopolysaccharide recognition - Nature Communications Phage therapy holds potential against Pseudomonas aeruginosa chronic lung infections in cystic fibrosis patients. Here, the authors demonstrate that biofilm heterogeneity limits phage effectiveness and identify mechanisms to overcome this barrier.

#Bacteriophages

Phage therapy holds potential against Pseudomonas aeruginosa chronic lung infections. Here, the authors show that biofilm heterogeneity limits phage effectiveness & identify mechanisms to overcome this barrier

@uminho.bsky.social

Directed evolution of phages in biofilms enhances Pseudomonas aeruginosa control through improved lipopolysaccharide recognition - Nature Communications Phage therapy holds potential against Pseudomonas aeruginosa chronic lung infections in cystic fibrosis patients. Here, the authors demonstrate that biofilm heterogeneity limits phage effectiveness and identify mechanisms to overcome this barrier.

#Bacteriophages

Phage therapy holds potential against Pseudomonas aeruginosa chronic lung infections. Here, the authors show that biofilm heterogeneity limits phage effectiveness & identify mechanisms to overcome this barrier

@uminho.bsky.social

Viruses Behave Totally Differently in Space and It Could Help Us Treat Superbugs on Earth Bacteria and viruses are locked in a slow motion battle aboard the ISS that looks nothing like life on the ground.

✨ In Lyon 🇫🇷 👉 We are treating this week the 100th patient with #phage therapy!
💯 complex medical histories
💯 patients for whom we had to find active pharmaceutical-grade #bacteriophages and customise the administration methods
💯 human stories
A great step and 🙏 to all those who made this possible!

Plaza and Intralytix Introduce Phage-Based Biocontrol Kit for Livestock Health | The Phage Intralytix and Plaza Feed & Crop Nutrition have agreed to integrate bacteriophage and probiotic technologies into specialised kits for livestock applications.

Intralytix has agreed with Plaza Feed & Crop Nutrition to integrate its bacteriophage products into specialised phage kits designed for livestock applications.

#Bacteriophages #PhageTherapy #AnimalHealth #LivestockProduction #AgriBiotech #FoodSafety #AMR

www.thephage.xyz/news/plaza-a...

Just found these in the basement. made when I was an undergrad #bacteriophages are the coolest! Also note that the duck is laying an egg (I think?). Questionable.

Are phages the future of medicine? Phages offer hope in the fight against resistant germs. TUM professor Bärbel Stecher provides insights into the current state of research.

In the German science program Quarks, Bärbel Stecher, professor of #IntestinalMicrobiome, explains how #bacteriophages target specific bacteria and their relevance for #AntibioticResistance and the #GutMicrobiome. Watch now: go.tum.de/112324

📷A.Eckert

Tiny viral switch offers hope against drug-resistant bacteria As antibiotic-resistant infections rise and are projected to cause up to 10 million deaths per year by 2050, scientists are looking to bacteriophages, viruses that infect bacteria, as an alternative.…

Tiny #viral switch offers hope against #drug-resistant #bacteria ...

| #drugresistance | #infections | #antibioticresistance | #bacteriophages | #phage | Via eurekalert .org

Bacteria Resisting Viral Infection Can Still Sink Carbon to Ocean Floor
www.newswise.com/articles/bac...

#Bacteriophages #oceans #marineecosystems #bacterialdefenses #CarbonExport #viruses #EvolutionaryEcology

Steering the course: targeting and exploiting surface receptors in phage therapy You have to enable JavaScript in your browser's settings in order to use the eReader.

Now available - PhD student Veronica Tran reviews the importance of identifying & reporting #phage receptors to build better therapeutic cocktails with diverse #bacteriophages for tough pathogens like #Pseudomonas
journals.asm.org/doi/epub/10....
@mcmasteriidr.bsky.social @mcmasternexus.bsky.social

Now available for educational use, THE GOOD VIRUS explores the global efforts of leading scientists combating one of the world's most pressing health challenges, antimicrobial-resistant infections (AMR), with bacteria’s ancient enemy: #bacteriophages. Order now: www.bullfrogfilms.com/catalog/gvc....

Virus battles drug-resistant infections It's an evolutionary battle, an endless competition for survival, that has spanned millions of years. Within this epic tale for the ages, the skillful characters are mighty, but very, very…

#Virus battles #drug-resistant #infections ...

| #DrugResistance | #bacteria | #Bacteriophages | #phages | Via @sciencex.bsky.social

Fishing for phages in botanical gardens Kompetensportalen, Lucat, Lupin, Lubas and LUCRIS. Those are the names of some of Lund University's administrative systems. They are now also the names of five new bacteriophages that have recently…

Fishing for #phages in #botanical gardens ...

| #bacteriophages | #virus | #bacteria | #infections | By @lund-university.bsky.social via @sciencex.bsky.social

Reprogramming resistance: phage-antibiotic synergy targets efflux systems in ESKAPEE pathogens | mBio Antimicrobial resistance (AMR) is one of the greatest threats to global health. If unaddressed, it is projected to cause over 39 million cumulative deaths globally by 2050 (1). While resistance is a broad and evolving problem, a small group of bacteria, collectively known as ESKAPEE pathogens, has e...

Phage-antibiotic synergy reprograms resistance by targeting efflux systems in ESKAPEE pathogens, offering a promising strategy against MDR/XDR bacteria. 🧬🦠 
#AntibioticResistance #PhageTherapy #Bacteriophages #MiniReview
📄 https://doi.org/10.1128/mbio.01822-25
👤 EVBC member: Robert Edwards

How viruses in the ocean change over time Ocean viruses, mostly those infecting bacteria, are key to healthy marine ecosystems. A new study of Korean coastal waters revealed surprising viral diversity using advanced genetic analysis.

How #viruses in the #ocean change over time ...

| #bacteriophages | #virus | #bacteria | #Puniceispirillum | #Micromonas | Via naturalsciencenews .com

Unlocking the Potential of Phages at The House of Lords Earlier this year, Prof Chloe James, a member of our KO AMR Scientific Advisory group, organised several events at the House of Lords that brought together global experts to discuss bacteriophages as ...

Have hosted a couple of events at #HouseofLords on #bacteriophages: still a lot of work to do on regulation, and not a magic bullet

microbiologysociety.org/blog/unlocki...

Phages with fully-synthetic DNA can be edited gene by gene A team led by University of Pittsburgh's Graham Hatfull has developed a method to construct bacteriophages with entirely synthetic genetic material, allowing researchers to add and subtract genes at…

#Phages with fully-synthetic #DNA can be edited gene by #gene ...

| #bacteriophages | #virus | #bacteria | #infections | Via @sciencex.bsky.social

Characterisation of four novel #bacteriophages targeting carbapenem-resistant #Klebsiella pneumoniae and their lytic activity alone and in combination

www.sciencedirect.com/science/arti... #OpenAccess #phages #MicroSky #MedSky #AntibioticResistance