So, bringing up a guy (Greg Jones) who has struck out 41% of time in almost 1100 Double and Triple A at bats is not going to solve the problem?

In Memoriam: Professor Greg Hannon (1964–2026) - Cancer Research UK Cambridge Institute Greg was already a world-renowned scientist when appointed Director, and for the community, he was a visionary leader, a cherished mentor, and a singular force of nature whose influence shaped the research landscape.

Very upsetting to hear the sad news of Greg Hannon’s passing. I always enjoyed our far too few conversations we had over the years. He had an interesting and insightful perspective on any science being discussed. He will be missed. www.cruk.cam.ac.uk/news/in-memo...

Why do you have Hall warming up if he's not going to face the lefthander there. I get leaving Miz in to face Duran and Willson Contreras. But then you leave Miz in to face the lefthander to load the bases on a walk, but then bring in Hall to face the right hander? What's the rationale for that?

Majkowski wasn't a complete stiff and he'd have the following guys lining up on offense.

RB: Green, Jones, Jacobs
WR: Sharpe, Adams, Jennings, Driver, Nelson
TE: Jackson, Finley, Kraft
OL: Bakhtiari, Sitton, Linsley, Lang, Clifton, Tauscher

Special teams - Desmond Howard

They'd be pretty good.

Abstract BACKGROUND Amid the declining clinical severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and diminishing public uptake of annual coronavirus disease 2019 (Covid-19) vaccines, contemporary evidence on vaccine effectiveness against clinically relevant outcomes is needed. METHODS We conducted an observational study that used the electronic health records of the Department of Veterans Affairs to evaluate the effectiveness of the 2024-2025 Covid-19 vaccine among veterans who received the Covid-19 and influenza vaccines on the same day (164,132 participants) and in an active-comparator group of veterans who received the influenza vaccine only (131,839 participants), between September 3 and December 31, 2024. Participants were followed for 180 days or until the occurrence of an outcome, whichever came first. We used inverse-probability-weighted models to estimate vaccine effectiveness (calculated as 1 minus the risk ratio) against Covid-19-associated emergency department visits, hospitalizations, and deaths at 6 months.

RESULTS At 6 months of follow-up, the estimated vaccine effectiveness was 29.3% (95% confidence interval [CI], 19.1 to 39.2) against Covid-19-associated emergency department visits (risk difference per 10,000 persons, 18.3; 95% CI, 10.8 to 27.6), 39.2% (95% Cl, 21.6 to 54.5) against Covid-19-associated hospitalizations (risk difference per 10,000 persons, 7.5; 95% CI, 3.4 to 13.0), and 64.0% (95% CI, 23.0 to 85.8) against Covid-19-associated deaths (risk difference per 10,000 persons, 2.2; 95% Cl, 0.5 to 6.9). Vaccine effectiveness against a composite of these outcomes was 28.3% (95% CI, 18.2 to 38.2), with a risk difference per 10,000 persons of 18.2 (95% Cl, 10.7 to 27.5). The Covid-19 vaccine was associated with decreased risks of these outcomes across prespecified subgroups defined according to age (<65 years, 65 to 75 years, and >75 years, the presence or absence of major coexisting conditions, and immunocompetence status. CONCLUSIONS In this national cohort of U.S. veterans, the receipt of the 2024-2025 Covid-19 vaccine was associated with decreased risks of severe clinical outcomes. (Funded by the Department of Veterans Affairs.)

According to the study’s authors, COVID vaccination was effective in all ALL groups and in persons with OR without major chronic conditions.

The study has been published in the New England Journal of Medicine. YES, it is PEER-REVIEWED.
• www.nejm.org/doi/full/10....

🧪🧵⬇️

Yes. WW1 draft registration signature is a good match.

ancestors.familysearch.org/en/9VRH-PK3/...

I thought for a second this might be him, but I'm not convinced by the handwriting. I've put the signature from your the census form your posted next to the signature of Harvey Arthur Deppen of Pennsylvania from the WW1 draft registration card. It's maybe worth a look.

Deletion of the Wnt regulator Znrf3 alters bone geometry without inducing high bone mass www.biorxiv.org/content/10.64898/2026.03...

The White Sox had 20 strikeouts, 5 ground outs to the infield, 2 infield pop outs, 2 infield base hits, and 2 home runs in the game.

The Brewers outfielders never handled a ball the whole game.

Yep, a mom's COVID shot during pregnancy protects her baby, a large study finds A 3-year study published in Pediatrics examined newborns in Norway. It found a clear benefit for the baby when mom gets a COVID vaccination during pregnancy.

A 3-year study published in Pediatrics examined newborns in Norway. It found a clear benefit for the baby when mom gets a COVID vaccination during pregnancy. n.pr/4uXOx6X

WELL NOW, would you look at that? A massive, 24-YEAR-LONG study of MORE THAN 1.2 MILLION people in Denmark found NO LINK between aluminum in childhood vaccines and autism, asthma, OR chronic disorders.

Aluminum is an ADJUVANT.

It ENHANCES your immune response to a vaccine.

That’s it.

Michael Bishop, Nobel Prize in Physiology or Medicine 1989: Official Lecture YouTube video by Nobel Prize

Very sad to hear of the passing today of our UCSF colleague Mike Bishop at the age of 90. A legendary and inspiring figure. He also led UCSF as Chancellor. Have a listen to his Nobel lecture. youtube.com/watch?v=CDv7...

Yes. As they give up an 18-0 run to a terrible Bulls team and trail in the 4th.

They will likely be heavily favored in 8 for the last 24 games. They have 6 games left against teams going all out to lose: @Bulls, @Utah, Utah, @Nets, Nets, Pacers. They also play the Mavs and the Grizzlies who are soft tanking.

That's 34 wins right there. 2-14 in the other games is doable

Prince Andrew's Arrest Across the pond in Britain, justice and accountability is a serious matter

Never in a million years did I ever fathom when I resurrected the Epstein story in 2018 that it would lead to first arrest of a British Royal in four centuries. Not since King Charles I was arrested in 1647.
open.substack.com/pub/jkbjourn...

A multioanel figure showing schematics for creating mice with an Lrp5 allele that lacks the class A repeats and LRP5 protein expression in mouse embryonic fibroblasts. Panel A: CRISPR/Cas9 targeting schematic of intron 17 and 19 of mouse Lrp5. Panel B: Model of wild-type and modified LRP5 proteins on the cell surface. Panel C: LRP5 protein expression in mouse embryonic fibroblasts.

Cassandra Diegel, @bartwilliams.bsky.social & co generated mice carrying an Lrp5 allele lacking the class A repeats and observed reduced bone mass and retinal vascularisation, suggesting an essential role for these repeats in normal #LRP5 function.

Read doi.org/10.1242/dmm....

It was Favrian. So were the interceptions.

I think a lot of teams would love to have him for the next 2-3 years. But if you trade for him, you almost have to extend him for 4 years and 270 million. I'm not sure a lot of teams are lining up to pay a guy who can't shoot and relies on athleticism 80 million dollars when he's 36 years old.

Giannis was part of the problem tonight. He was outhustled and was Bobby Portis-like on defense.

Plastic associated endocrine disruptors reduce Nicastrin protein and potentiate inflammation in hidradenitis suppurativa skin disease Nature Communications - Here, the authors find that low Nicastrin protein in the disease Hidradenitis Suppurativa enhances immune sensitivity and may be caused by exposure to plastic-associated...

www.nature.com/articles/s41...

Ever since Middleton got hurt in the 2022 Bulls playoff series, nothing has gone right. They were probably going to repeat that year had he stayed healthy. Instead, they lose in 7 to Boston and then weren't been healthy for a playoff series since. This is just the bitter end.

This loss on Giannis. Three possessions in a row - Missed 3 of 4 FTs and an embarrassing turnover on a bounce pass that 3 different Rockets could have picked off.

Is this correct? I really don't want to believe this because this kind of skewed officiating should trigger every warning bell for illegal betting.

What is the actual number?

It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social

Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r

There is a reason he gets so many chances with the bases loaded. You will almost always pitch around the guy in front of him because he is the worst offensive regular in MLB this year (at least by OPS).

Photo of @dr-kevin-pruitt.bsky.social standing in front of slides from the podium where he gave a seminar at the Van Andel Institute.

Gave a seminar at the Van Andel Institute and greatly enjoyed meeting with pioneers in the field of Wnt signaling @sgraingerphd.bsky.social and @bartwilliams.bsky.social. Also reunited with amazing colleagues in the fields of epigenetics and RAS biology. What a vibrant research community @vai.org!

Phillies are only 4 back in the loss column if this score holds tonight.

Durbin hit the ball hard several times today, and he's still a better matchup than Seigler against a RH. Seigler's OPS against righthanders is 498 on 49 at-bats. Durbin's OPS against righties is 692 in 279 plate appearance. It's the equivalent of pinch hitting for a C- player with an F.

I'm not saying you did. I'm just puzzled about why Dame's mouthpiece (Haynes) would frame it this way.