Happy to share this work from @alexneaverson.bsky.social where she has dissected the timing and relative contribution of the organiser and its derivates to multiple aspects of early neural development:
www.biorxiv.org/content/10.6...
Posts by Chaitanya Dingare
Congratulations! Fantastic news! Hope to see you in Freiburg at some point.
The Frenster Lab is here! 🍾 I am so excited to start my #EmmyNoether funded group at @uni-freiburg.de this summer. Our group studies #CellCompetition dynamics during embryonic development using #gastruloids from multiple species. Thanks to the @dfg.de for creating this opportunity! FrensterLab.com
Very happy to announce that I will be joining the Faculty of Biology & @cibss.bsky.social at @uni-freiburg.de as an Emmy-Noether funded group leader.
We will tackle the molecular and genetic basis of developmental timing and size control using diverse Oryzias species. We are hiring at all levels !
Hi bsky!
How do cells coordinate fate with migration during development? 🐣 Turns out EMT doesn't just drive cell behaviour changes... it actively primes BMP signalling competence, creating a reciprocal coupling that drives collective invasion!
(@bensteventon.bsky.social lab)
tinyurl.com/2ncc8zap
Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis: Molecular Cell www.cell.com/molecular-ce...
Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead!
www.science.org/doi/10.1126/...
Hi bsky!
Do embryonic tissues have backup plans🔀? Gastruloids (model of body elongation) can build an axis through different cellular mechanisms when on adherent substrates instead of free floating. A case of developmental plasticity!
w/ A. Delahaye & @bensteventon.bsky.social
shorturl.at/v01DO
Which features of tissue flows are most robust and how do they emerge from #EpithelialMechanics?
I’m @alex-plum.bsky.social (@mattiaserra.bsky.social group) and I’ll be sharing some papers on characterizing and controlling avian gastrulation flows.
Speaking of time, @osvaldo-chara.bsky.social 's lab recently developed a new method, ForSys, that uses all available dynamic information. It also tracks the elements of the tissue over time and uses their movement to further inform the stress inference algorithm.
bsky.app/profile/epim...
Live imaging of late-stage preimplantation human embryos reveals de novo mitotic errors - @niakanlab.bsky.social @loke-ctr.bsky.social go.nature.com/3JdRdu8
Congratulations Ahmed and colleagues in the @niakanlab.bsky.social on this beautiful work tracking mitotic errors by live imaging the human embryos!
Like Wnt signalling? How about Notch? How about both together (Wntch!)... in gastruloids? Come and and apply for a PhD studentship with us in Liverpool! Applications open 30th October! tinyurl.com/3bpx3y2b
A developmental atlas of zebrafish gills links early vascular patterning to adult architecture
Read this #LifelongDevSI #OA Research Article by Mathieu Preußner @mathpreu.bsky.social, Virginie Lecaudey @vlecaudey.bsky.social and colleagues:
journals.biologists.com/dev/article/...
Congratulations @vlecaudey.bsky.social @mathpreu.bsky.social
Congratulations!
1🧵
Excited to share my first PhD paper, published in @dev-journal.bsky.social
What if fish gills —often overlook —hold secrets about development, patterning, and function?
We uncovered how early patterning shapes adult gill architecture.
journals.biologists.com/dev/article/...
#DevBio #Zebrafish
New preprint from the Lecaudey lab by first authors Anna Mertens and Nicola Moratscheck, with the help of other former members including @chaitanyadingare.bsky.social uncovering the role of integrin-laminin interactions during epithelial collective cell migration!
(1/8) Very Happy to share our lab’s 3D post-implantation human embryo model, made via signalling reprograming!
🙌 Huge thanks to the entire team and our collaborators, special shout-out to @cc0447.bsky.social (led the work) and @jinjin-0101.bsky.social (comp. analysis).
www.cell.com/cell-stem-ce...
This is a rigorous piece of work, completed with help of current @vlecaudey.bsky.social lab members.
I combined the genetics with live imaging approaches to delineate how hippo pathway and its regulators control the cell number. I have generated a few essential tools including the zebrafish specific yap1 antibody (works really well).
I have used the zebrafish lateral line primordium as a model. Reason - it contains only 100-120 cells to begin with so much easier to follow the mechanisms that controls the cell number.
www.biorxiv.org/content/10.1... late post! Parts of my PhD thesis are now in a preprint. Just imagine if each cell of your organs decides to undergo some extra divisions while being formed, how would they look and what prevents that from happening? This is exactly what I have shown in my work.
Patterned integrin-laminin adhesion coordinates epithelial collective cell migration www.biorxiv.org/content/10.1101/2025.09....
@vlecaudey.bsky.social !
Congratulations!
Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social
GATA6 Mediates Endoderm and Mesoderm Progenitor Fate Driven by WNT and NODAL Signaling www.biorxiv.org/content/10.1101/2025.06....
An advanced head-to-tail mouse embryo model with hypoxia-mediated neural patterning www.biorxiv.org/content/10.1101/2025.06....